Gut microbiota in early life and its influence on health and disease: a position paper by the Malaysian Working Group on Gastrointestinal Health
The role of gut microbiota in early life and its impact on gut health and subsequent diseases remain unclear. There is a lack of research and awareness in this area, especially in the Asia-Pacific region, including Malaysia. This paper reports the position of a Malaysian Working Group on some key is...
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| Format: | Article |
| Language: | English |
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John Wiley & Sons Australia
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/59656/ http://psasir.upm.edu.my/id/eprint/59656/1/Gut%20microbiota%20in%20early%20life%20and%20its%20influence%20on%20health%20and%20disease%20a%20position%20paper%20by%20the%20Malaysian%20Working%20Group%20on%20Gastrointestinal%20Health.pdf |
| _version_ | 1848853982213046272 |
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| author | Lee, Yeong Yeh Hassan, Siti Asma' Ismail, Intan Hakimah Chong, Sze Yee Raja Ali, Raja Affendi Amin Nordin, Syafinaz Lee, Way Seah Abdul Majid, Noorizan |
| author_facet | Lee, Yeong Yeh Hassan, Siti Asma' Ismail, Intan Hakimah Chong, Sze Yee Raja Ali, Raja Affendi Amin Nordin, Syafinaz Lee, Way Seah Abdul Majid, Noorizan |
| author_sort | Lee, Yeong Yeh |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The role of gut microbiota in early life and its impact on gut health and subsequent diseases remain unclear. There is a lack of research and awareness in this area, especially in the Asia-Pacific region, including Malaysia. This paper reports the position of a Malaysian Working Group on some key issues surrounding gut microbiota in early life and its role in gut health and diseases, as well as experts’ stand on probiotics and prebiotics. The group reached a consensus that certain factors, including elective caesarean; premature deliveries; complementary feeding; use of antibiotics, prebiotics and/or probiotics; and exposure to the external environmental, have an impact on gut microbiota in early life. However, as evidence is lacking, especially from the Asia-Pacific region, further studies are needed to understand how gut microbiota in early life affects subsequent diseases, including allergy, inflammatory bowel disease, obesity and infantile colic. Lastly, although beneficial in acute diarrhoeal disease and probably allergic eczema, probiotics (and/or prebiotics) should be used cautiously in other gut dysbiotic conditions until more data are available. |
| first_indexed | 2025-11-15T11:02:37Z |
| format | Article |
| id | upm-59656 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T11:02:37Z |
| publishDate | 2017 |
| publisher | John Wiley & Sons Australia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-596562018-03-15T02:54:28Z http://psasir.upm.edu.my/id/eprint/59656/ Gut microbiota in early life and its influence on health and disease: a position paper by the Malaysian Working Group on Gastrointestinal Health Lee, Yeong Yeh Hassan, Siti Asma' Ismail, Intan Hakimah Chong, Sze Yee Raja Ali, Raja Affendi Amin Nordin, Syafinaz Lee, Way Seah Abdul Majid, Noorizan The role of gut microbiota in early life and its impact on gut health and subsequent diseases remain unclear. There is a lack of research and awareness in this area, especially in the Asia-Pacific region, including Malaysia. This paper reports the position of a Malaysian Working Group on some key issues surrounding gut microbiota in early life and its role in gut health and diseases, as well as experts’ stand on probiotics and prebiotics. The group reached a consensus that certain factors, including elective caesarean; premature deliveries; complementary feeding; use of antibiotics, prebiotics and/or probiotics; and exposure to the external environmental, have an impact on gut microbiota in early life. However, as evidence is lacking, especially from the Asia-Pacific region, further studies are needed to understand how gut microbiota in early life affects subsequent diseases, including allergy, inflammatory bowel disease, obesity and infantile colic. Lastly, although beneficial in acute diarrhoeal disease and probably allergic eczema, probiotics (and/or prebiotics) should be used cautiously in other gut dysbiotic conditions until more data are available. John Wiley & Sons Australia 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/59656/1/Gut%20microbiota%20in%20early%20life%20and%20its%20influence%20on%20health%20and%20disease%20a%20position%20paper%20by%20the%20Malaysian%20Working%20Group%20on%20Gastrointestinal%20Health.pdf Lee, Yeong Yeh and Hassan, Siti Asma' and Ismail, Intan Hakimah and Chong, Sze Yee and Raja Ali, Raja Affendi and Amin Nordin, Syafinaz and Lee, Way Seah and Abdul Majid, Noorizan (2017) Gut microbiota in early life and its influence on health and disease: a position paper by the Malaysian Working Group on Gastrointestinal Health. Journal of Paediatrics and Child Health, 53 (12). pp. 1152-1158. ISSN 1034-4810; ESSN: 1440-1754 http://onlinelibrary.wiley.com/wol1/doi/10.1111/jpc.13640/abstract 10.1111/jpc.13640 |
| spellingShingle | Lee, Yeong Yeh Hassan, Siti Asma' Ismail, Intan Hakimah Chong, Sze Yee Raja Ali, Raja Affendi Amin Nordin, Syafinaz Lee, Way Seah Abdul Majid, Noorizan Gut microbiota in early life and its influence on health and disease: a position paper by the Malaysian Working Group on Gastrointestinal Health |
| title | Gut microbiota in early life and its influence on health and disease: a position paper by the Malaysian Working Group on Gastrointestinal Health |
| title_full | Gut microbiota in early life and its influence on health and disease: a position paper by the Malaysian Working Group on Gastrointestinal Health |
| title_fullStr | Gut microbiota in early life and its influence on health and disease: a position paper by the Malaysian Working Group on Gastrointestinal Health |
| title_full_unstemmed | Gut microbiota in early life and its influence on health and disease: a position paper by the Malaysian Working Group on Gastrointestinal Health |
| title_short | Gut microbiota in early life and its influence on health and disease: a position paper by the Malaysian Working Group on Gastrointestinal Health |
| title_sort | gut microbiota in early life and its influence on health and disease: a position paper by the malaysian working group on gastrointestinal health |
| url | http://psasir.upm.edu.my/id/eprint/59656/ http://psasir.upm.edu.my/id/eprint/59656/ http://psasir.upm.edu.my/id/eprint/59656/ http://psasir.upm.edu.my/id/eprint/59656/1/Gut%20microbiota%20in%20early%20life%20and%20its%20influence%20on%20health%20and%20disease%20a%20position%20paper%20by%20the%20Malaysian%20Working%20Group%20on%20Gastrointestinal%20Health.pdf |