Computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (CTLM)

Computed tomography laser mammography (Eid et al. Egyp J Radiol Nucl Med, 37(1): p. 633–643, 1) is a non-invasive imaging modality for breast cancer diagnosis, which is time-consuming and challenging for the radiologist to interpret the images. Some issues have increased the missed diagnosis of radi...

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Main Authors: Jalalian, Afsaneh, Mashohor, Syamsiah, Mahmud, Rozi, Karasfi, Babak, Saripan, M. Iqbal, Ramli, Abdul Rahman
Format: Article
Language:English
Published: Springer 2017
Online Access:http://psasir.upm.edu.my/id/eprint/59538/
http://psasir.upm.edu.my/id/eprint/59538/1/Computer-assisted%20diagnosis%20system%20for%20breast%20cancer%20in%20computed%20tomography%20laser%20mammography%20%28CTLM%29.pdf
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author Jalalian, Afsaneh
Mashohor, Syamsiah
Mahmud, Rozi
Karasfi, Babak
Saripan, M. Iqbal
Ramli, Abdul Rahman
author_facet Jalalian, Afsaneh
Mashohor, Syamsiah
Mahmud, Rozi
Karasfi, Babak
Saripan, M. Iqbal
Ramli, Abdul Rahman
author_sort Jalalian, Afsaneh
building UPM Institutional Repository
collection Online Access
description Computed tomography laser mammography (Eid et al. Egyp J Radiol Nucl Med, 37(1): p. 633–643, 1) is a non-invasive imaging modality for breast cancer diagnosis, which is time-consuming and challenging for the radiologist to interpret the images. Some issues have increased the missed diagnosis of radiologists in visual manner assessment in CTLM images, such as technical reasons which are related to imaging quality and human error due to the structural complexity in appearance. The purpose of this study is to develop a computer-aided diagnosis framework to enhance the performance of radiologist in the interpretation of CTLM images. The proposed CAD system contains three main stages including segmentation of volume of interest (VOI), feature extraction and classification. A 3D Fuzzy segmentation technique has been implemented to extract the VOI. The shape and texture of angiogenesis in CTLM images are significant characteristics to differentiate malignancy or benign lesions. The 3D compactness features and 3D Grey Level Co-occurrence matrix (GLCM) have been extracted from VOIs. Multilayer perceptron neural network (MLPNN) pattern recognition has developed for classification of the normal and abnormal lesion in CTLM images. The performance of the proposed CAD system has been measured with different metrics including accuracy, sensitivity, and specificity and area under receiver operative characteristics (AROC), which are 95.2, 92.4, 98.1, and 0.98%, respectively.
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spelling upm-595382018-03-08T04:35:19Z http://psasir.upm.edu.my/id/eprint/59538/ Computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (CTLM) Jalalian, Afsaneh Mashohor, Syamsiah Mahmud, Rozi Karasfi, Babak Saripan, M. Iqbal Ramli, Abdul Rahman Computed tomography laser mammography (Eid et al. Egyp J Radiol Nucl Med, 37(1): p. 633–643, 1) is a non-invasive imaging modality for breast cancer diagnosis, which is time-consuming and challenging for the radiologist to interpret the images. Some issues have increased the missed diagnosis of radiologists in visual manner assessment in CTLM images, such as technical reasons which are related to imaging quality and human error due to the structural complexity in appearance. The purpose of this study is to develop a computer-aided diagnosis framework to enhance the performance of radiologist in the interpretation of CTLM images. The proposed CAD system contains three main stages including segmentation of volume of interest (VOI), feature extraction and classification. A 3D Fuzzy segmentation technique has been implemented to extract the VOI. The shape and texture of angiogenesis in CTLM images are significant characteristics to differentiate malignancy or benign lesions. The 3D compactness features and 3D Grey Level Co-occurrence matrix (GLCM) have been extracted from VOIs. Multilayer perceptron neural network (MLPNN) pattern recognition has developed for classification of the normal and abnormal lesion in CTLM images. The performance of the proposed CAD system has been measured with different metrics including accuracy, sensitivity, and specificity and area under receiver operative characteristics (AROC), which are 95.2, 92.4, 98.1, and 0.98%, respectively. Springer 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/59538/1/Computer-assisted%20diagnosis%20system%20for%20breast%20cancer%20in%20computed%20tomography%20laser%20mammography%20%28CTLM%29.pdf Jalalian, Afsaneh and Mashohor, Syamsiah and Mahmud, Rozi and Karasfi, Babak and Saripan, M. Iqbal and Ramli, Abdul Rahman (2017) Computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (CTLM). Journal of Digital Imaging, 30 (6). pp. 796-811. ISSN 0897-1889; ESSN: 1618-727X https://link.springer.com/article/10.1007/s10278-017-9958-5 10.1007/s10278-017-9958-5
spellingShingle Jalalian, Afsaneh
Mashohor, Syamsiah
Mahmud, Rozi
Karasfi, Babak
Saripan, M. Iqbal
Ramli, Abdul Rahman
Computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (CTLM)
title Computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (CTLM)
title_full Computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (CTLM)
title_fullStr Computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (CTLM)
title_full_unstemmed Computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (CTLM)
title_short Computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (CTLM)
title_sort computer-assisted diagnosis system for breast cancer in computed tomography laser mammography (ctlm)
url http://psasir.upm.edu.my/id/eprint/59538/
http://psasir.upm.edu.my/id/eprint/59538/
http://psasir.upm.edu.my/id/eprint/59538/
http://psasir.upm.edu.my/id/eprint/59538/1/Computer-assisted%20diagnosis%20system%20for%20breast%20cancer%20in%20computed%20tomography%20laser%20mammography%20%28CTLM%29.pdf