Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property

DSN1 is a spindle pole body component that functions in the chromosomal segregation process of yeast. The effect of additional DSN1 gene dosage on the yeast cell has yet to be established. The work from this study indicated that an extra gene dosage of DSN1 caused abnormalities in both cellular grow...

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Main Authors: Yiap, Beow Chin, Wong, Clemente Michael Vui Ling, Mohd Yusuf, Hirzun, Abdul Rahim, Raha
Format: Article
Language:English
Published: Malaysian Society for Molecular Biology and Biotechnology 2004
Online Access:http://psasir.upm.edu.my/id/eprint/58522/
http://psasir.upm.edu.my/id/eprint/58522/1/Extra%20dose%20of%20Dsn1p%20%28Yir010wp%29%20expressed%20from%20episomal%20plasmid%20in%20normal%20Saccharomyces%20cerevisiae%20diploid.pdf
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author Yiap, Beow Chin
Wong, Clemente Michael Vui Ling
Mohd Yusuf, Hirzun
Abdul Rahim, Raha
author_facet Yiap, Beow Chin
Wong, Clemente Michael Vui Ling
Mohd Yusuf, Hirzun
Abdul Rahim, Raha
author_sort Yiap, Beow Chin
building UPM Institutional Repository
collection Online Access
description DSN1 is a spindle pole body component that functions in the chromosomal segregation process of yeast. The effect of additional DSN1 gene dosage on the yeast cell has yet to be established. The work from this study indicated that an extra gene dosage of DSN1 caused abnormalities in both cellular growth and budding pattern. The yeast cells carrying an additional copy of DSN1 gene have an increased growth rate and they formed a highly retarded multiple bud complex. These phenomena suggest possible growth stimulating property of the gene product.
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institution Universiti Putra Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T10:57:40Z
publishDate 2004
publisher Malaysian Society for Molecular Biology and Biotechnology
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spelling upm-585222018-01-22T02:07:52Z http://psasir.upm.edu.my/id/eprint/58522/ Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property Yiap, Beow Chin Wong, Clemente Michael Vui Ling Mohd Yusuf, Hirzun Abdul Rahim, Raha DSN1 is a spindle pole body component that functions in the chromosomal segregation process of yeast. The effect of additional DSN1 gene dosage on the yeast cell has yet to be established. The work from this study indicated that an extra gene dosage of DSN1 caused abnormalities in both cellular growth and budding pattern. The yeast cells carrying an additional copy of DSN1 gene have an increased growth rate and they formed a highly retarded multiple bud complex. These phenomena suggest possible growth stimulating property of the gene product. Malaysian Society for Molecular Biology and Biotechnology 2004 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/58522/1/Extra%20dose%20of%20Dsn1p%20%28Yir010wp%29%20expressed%20from%20episomal%20plasmid%20in%20normal%20Saccharomyces%20cerevisiae%20diploid.pdf Yiap, Beow Chin and Wong, Clemente Michael Vui Ling and Mohd Yusuf, Hirzun and Abdul Rahim, Raha (2004) Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property. Asia Pacific Journal of Molecular Biology and Biotechnology, 12 (1&2). pp. 43-47. ISSN 0128-7451 http://www.msmbb.org.my/apjmbb/html12/12g.htm
spellingShingle Yiap, Beow Chin
Wong, Clemente Michael Vui Ling
Mohd Yusuf, Hirzun
Abdul Rahim, Raha
Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property
title Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property
title_full Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property
title_fullStr Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property
title_full_unstemmed Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property
title_short Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property
title_sort extra dose of dsn1p (yir010wp) expressed from episomal plasmid in normal saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property
url http://psasir.upm.edu.my/id/eprint/58522/
http://psasir.upm.edu.my/id/eprint/58522/
http://psasir.upm.edu.my/id/eprint/58522/1/Extra%20dose%20of%20Dsn1p%20%28Yir010wp%29%20expressed%20from%20episomal%20plasmid%20in%20normal%20Saccharomyces%20cerevisiae%20diploid.pdf