Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate
The environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal structu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Faculty of Food Science and Technology, Universiti Putra Malaysia
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/58362/ http://psasir.upm.edu.my/id/eprint/58362/1/%2856%29.pdf |
| _version_ | 1848853625246318592 |
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| author | Sabullah, Mohd Khalizan Ahmad, Siti Aqlima Abd. Shukor, Mohd. Yunus Gansau, Jualang @ Azlan Abdullah Shamaan, Nor Aripin Khalid, Ariff Sulaiman, Mohd Rosni |
| author_facet | Sabullah, Mohd Khalizan Ahmad, Siti Aqlima Abd. Shukor, Mohd. Yunus Gansau, Jualang @ Azlan Abdullah Shamaan, Nor Aripin Khalid, Ariff Sulaiman, Mohd Rosni |
| author_sort | Sabullah, Mohd Khalizan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal structure of the hepatocyte. However, at the concentrations of 0.5, 1.0 and 5.0 mg/L CuSO4, the hepatostructure was significantly affected, as shown by the increasing number of dilation and congestion of sinusoids, vacuolation, macrophage activities and peliosis. The damage level and HSI value were increased while the number of hepatic nuclei per mm2 was decreased with the increasing of copper concentration. In conclusion, this study shows that the degree of liver damage in P.javanicus is dependent to the dose exposure. |
| first_indexed | 2025-11-15T10:56:57Z |
| format | Article |
| id | upm-58362 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:56:57Z |
| publishDate | 2017 |
| publisher | Faculty of Food Science and Technology, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-583622018-01-12T04:10:23Z http://psasir.upm.edu.my/id/eprint/58362/ Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate Sabullah, Mohd Khalizan Ahmad, Siti Aqlima Abd. Shukor, Mohd. Yunus Gansau, Jualang @ Azlan Abdullah Shamaan, Nor Aripin Khalid, Ariff Sulaiman, Mohd Rosni The environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal structure of the hepatocyte. However, at the concentrations of 0.5, 1.0 and 5.0 mg/L CuSO4, the hepatostructure was significantly affected, as shown by the increasing number of dilation and congestion of sinusoids, vacuolation, macrophage activities and peliosis. The damage level and HSI value were increased while the number of hepatic nuclei per mm2 was decreased with the increasing of copper concentration. In conclusion, this study shows that the degree of liver damage in P.javanicus is dependent to the dose exposure. Faculty of Food Science and Technology, Universiti Putra Malaysia 2017 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/58362/1/%2856%29.pdf Sabullah, Mohd Khalizan and Ahmad, Siti Aqlima and Abd. Shukor, Mohd. Yunus and Gansau, Jualang @ Azlan Abdullah and Shamaan, Nor Aripin and Khalid, Ariff and Sulaiman, Mohd Rosni (2017) Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate. International Food Research Journal, 24 (3). pp. 1314-1320. ISSN 1985-4668; ESSN: 2231-7546 http://www.ifrj.upm.edu.my/24%20(03)%202017/(56).pdf |
| spellingShingle | Sabullah, Mohd Khalizan Ahmad, Siti Aqlima Abd. Shukor, Mohd. Yunus Gansau, Jualang @ Azlan Abdullah Shamaan, Nor Aripin Khalid, Ariff Sulaiman, Mohd Rosni Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
| title | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
| title_full | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
| title_fullStr | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
| title_full_unstemmed | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
| title_short | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
| title_sort | alteration in morphological features of puntius javanicus liver exposed to copper sulfate |
| url | http://psasir.upm.edu.my/id/eprint/58362/ http://psasir.upm.edu.my/id/eprint/58362/ http://psasir.upm.edu.my/id/eprint/58362/1/%2856%29.pdf |