Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor

Lipase-catalyzed production of palm esters by alcoholysis of palm oil with oleyl alcohol in n-hexane was performed in 2 L stirred-tank reactor (STR). Investigation on the performance of reactor operation was carried out in batch mode STR with single impeller mounted on the centrally located shaft. R...

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Main Authors: Keng, Pei Sin, Basri, Mahiran, Ariff, Arbakariya, Abdul Rahman, Mohd Basyaruddin, Raja Abdul Rahman, Raja Noor Zaliha, Salleh, Abu Bakar
Format: Article
Language:English
Published: Elsevier 2008
Online Access:http://psasir.upm.edu.my/id/eprint/5805/
http://psasir.upm.edu.my/id/eprint/5805/1/Scale.pdf
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author Keng, Pei Sin
Basri, Mahiran
Ariff, Arbakariya
Abdul Rahman, Mohd Basyaruddin
Raja Abdul Rahman, Raja Noor Zaliha
Salleh, Abu Bakar
author_facet Keng, Pei Sin
Basri, Mahiran
Ariff, Arbakariya
Abdul Rahman, Mohd Basyaruddin
Raja Abdul Rahman, Raja Noor Zaliha
Salleh, Abu Bakar
author_sort Keng, Pei Sin
building UPM Institutional Repository
collection Online Access
description Lipase-catalyzed production of palm esters by alcoholysis of palm oil with oleyl alcohol in n-hexane was performed in 2 L stirred-tank reactor (STR). Investigation on the performance of reactor operation was carried out in batch mode STR with single impeller mounted on the centrally located shaft. Rushton turbine (RT) impellers provide the highest reaction yield (95.8%) at lower agitation speed as compared to AL-hydrofoil (AL-H) and 2-bladed elephant ear (EE) impellers. Homogenous enzyme particles suspension was obtained at 250 rpm by using RT impeller. At higher impeller speed, the shear effect on the enzyme particles caused by agitation has decreased the reaction performance. Palm esters reaction mixture in STR follows Newtons’ law due to the linear relation between the shear stress (s) and shear rate (dt/dy). High stability of Lipozyme RM IM was observed as shown by its ability to be repeatedly used to give high percentage yield (79%) of palm esters even after 15 cycles of reaction. The process was successfully scale-up to 75 L STR (50 L working volume) based on a constant impeller tip speed approach, which gave the yield of 97.2% after 5 h reaction time.
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institution Universiti Putra Malaysia
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spelling upm-58052016-09-28T02:15:43Z http://psasir.upm.edu.my/id/eprint/5805/ Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor Keng, Pei Sin Basri, Mahiran Ariff, Arbakariya Abdul Rahman, Mohd Basyaruddin Raja Abdul Rahman, Raja Noor Zaliha Salleh, Abu Bakar Lipase-catalyzed production of palm esters by alcoholysis of palm oil with oleyl alcohol in n-hexane was performed in 2 L stirred-tank reactor (STR). Investigation on the performance of reactor operation was carried out in batch mode STR with single impeller mounted on the centrally located shaft. Rushton turbine (RT) impellers provide the highest reaction yield (95.8%) at lower agitation speed as compared to AL-hydrofoil (AL-H) and 2-bladed elephant ear (EE) impellers. Homogenous enzyme particles suspension was obtained at 250 rpm by using RT impeller. At higher impeller speed, the shear effect on the enzyme particles caused by agitation has decreased the reaction performance. Palm esters reaction mixture in STR follows Newtons’ law due to the linear relation between the shear stress (s) and shear rate (dt/dy). High stability of Lipozyme RM IM was observed as shown by its ability to be repeatedly used to give high percentage yield (79%) of palm esters even after 15 cycles of reaction. The process was successfully scale-up to 75 L STR (50 L working volume) based on a constant impeller tip speed approach, which gave the yield of 97.2% after 5 h reaction time. Elsevier 2008 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/5805/1/Scale.pdf Keng, Pei Sin and Basri, Mahiran and Ariff, Arbakariya and Abdul Rahman, Mohd Basyaruddin and Raja Abdul Rahman, Raja Noor Zaliha and Salleh, Abu Bakar (2008) Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor. Bioresource Technology, 99 (14). pp. 6097-6104. ISSN 0960-8524; ESSN: 1873-2976 http://www.sciencedirect.com/science/article/pii/S0960852407010735 10.1016/j.biortech.2007.12.049
spellingShingle Keng, Pei Sin
Basri, Mahiran
Ariff, Arbakariya
Abdul Rahman, Mohd Basyaruddin
Raja Abdul Rahman, Raja Noor Zaliha
Salleh, Abu Bakar
Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor
title Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor
title_full Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor
title_fullStr Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor
title_full_unstemmed Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor
title_short Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor
title_sort scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor
url http://psasir.upm.edu.my/id/eprint/5805/
http://psasir.upm.edu.my/id/eprint/5805/
http://psasir.upm.edu.my/id/eprint/5805/
http://psasir.upm.edu.my/id/eprint/5805/1/Scale.pdf