The past and current updates on diagnostic aspects of osteoarthritis
Osteoarthritis (OA) is a progressive joint disease leading to the destruction of joint structures, which in turn causes severe and chronic pain to the patient. Since OA is a troubling and disruptive disease, numerous researches have been done into diagnosing this disease, both in the early and the l...
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| Format: | Article |
| Language: | English |
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Veterinary Association Malaysia
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/56838/ http://psasir.upm.edu.my/id/eprint/56838/1/JVM-2017-Dr-Lau.pdf |
| _version_ | 1848853197741883392 |
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| author | Tan, Wei Miao Lau, Seng Fong Md. Ajat, Mohd Mokrish Mansor, Rozaihan Megat Abdul Rani, Puteri Azaziah Ng, Angela Min Hwei Rahmad, Norasfaliza |
| author_facet | Tan, Wei Miao Lau, Seng Fong Md. Ajat, Mohd Mokrish Mansor, Rozaihan Megat Abdul Rani, Puteri Azaziah Ng, Angela Min Hwei Rahmad, Norasfaliza |
| author_sort | Tan, Wei Miao |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Osteoarthritis (OA) is a progressive joint disease leading to the destruction of joint structures, which in turn causes severe and chronic pain to the patient. Since OA is a troubling and disruptive disease, numerous researches have been done into diagnosing this disease, both in the early and the late stages of the disease. Diagnostic modalities such as radiography, computed-tomography (CT), micro-computed tomography (μ-CT), and magnetic resonance imaging (MRI) have been used in OA research. Not only that, more advance measurements and criteria have been established to standardize OA research. Currently, the OA research has been delving into proteomic studies to search for potential disease biomarkers. Biomarkers such as urinary C-terminal telopeptide of collagen type 2 (uCTX-II) and cartilage oligometric protein (COMP) have shown potential to be both diagnostic and prognostic biomarkers. For this review paper, the developments in diagnostic modalities are discussed focusing more on proteomic and biomarker studies. |
| first_indexed | 2025-11-15T10:50:09Z |
| format | Article |
| id | upm-56838 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:50:09Z |
| publishDate | 2017 |
| publisher | Veterinary Association Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-568382017-09-05T09:07:12Z http://psasir.upm.edu.my/id/eprint/56838/ The past and current updates on diagnostic aspects of osteoarthritis Tan, Wei Miao Lau, Seng Fong Md. Ajat, Mohd Mokrish Mansor, Rozaihan Megat Abdul Rani, Puteri Azaziah Ng, Angela Min Hwei Rahmad, Norasfaliza Osteoarthritis (OA) is a progressive joint disease leading to the destruction of joint structures, which in turn causes severe and chronic pain to the patient. Since OA is a troubling and disruptive disease, numerous researches have been done into diagnosing this disease, both in the early and the late stages of the disease. Diagnostic modalities such as radiography, computed-tomography (CT), micro-computed tomography (μ-CT), and magnetic resonance imaging (MRI) have been used in OA research. Not only that, more advance measurements and criteria have been established to standardize OA research. Currently, the OA research has been delving into proteomic studies to search for potential disease biomarkers. Biomarkers such as urinary C-terminal telopeptide of collagen type 2 (uCTX-II) and cartilage oligometric protein (COMP) have shown potential to be both diagnostic and prognostic biomarkers. For this review paper, the developments in diagnostic modalities are discussed focusing more on proteomic and biomarker studies. Veterinary Association Malaysia 2017 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/56838/1/JVM-2017-Dr-Lau.pdf Tan, Wei Miao and Lau, Seng Fong and Md. Ajat, Mohd Mokrish and Mansor, Rozaihan and Megat Abdul Rani, Puteri Azaziah and Ng, Angela Min Hwei and Rahmad, Norasfaliza (2017) The past and current updates on diagnostic aspects of osteoarthritis. Jurnal Veterinar Malaysia, 29 (1). pp. 7-12. ISSN 9128-2506 http://jvm.vam.org.my/wp-content/uploads/2017/07/JVM-2017-Dr-Lau.pdf |
| spellingShingle | Tan, Wei Miao Lau, Seng Fong Md. Ajat, Mohd Mokrish Mansor, Rozaihan Megat Abdul Rani, Puteri Azaziah Ng, Angela Min Hwei Rahmad, Norasfaliza The past and current updates on diagnostic aspects of osteoarthritis |
| title | The past and current updates on diagnostic aspects of osteoarthritis |
| title_full | The past and current updates on diagnostic aspects of osteoarthritis |
| title_fullStr | The past and current updates on diagnostic aspects of osteoarthritis |
| title_full_unstemmed | The past and current updates on diagnostic aspects of osteoarthritis |
| title_short | The past and current updates on diagnostic aspects of osteoarthritis |
| title_sort | past and current updates on diagnostic aspects of osteoarthritis |
| url | http://psasir.upm.edu.my/id/eprint/56838/ http://psasir.upm.edu.my/id/eprint/56838/ http://psasir.upm.edu.my/id/eprint/56838/1/JVM-2017-Dr-Lau.pdf |