Adverse effects of imidocarb dipropionate (Imizol) in a dog

One of 13 healthy dogs used in a pharmacokinetic study of imidocarb dipropionate died due to difficulty in breathing, tachycardia, weakness and profuse diarrhoea. Autopsy findings showed marked pulmonary congestion and oedema. Kidneys were grossly enlarged and markedly congested with extensive haem...

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Main Authors: Abdullah, A. Salam, Abdul Rahman, Sheikh Omar, Desmond, Baggot J., Saad, Mohd Zamri
Format: Article
Language:English
Published: Kluwer Academic Publishers 1984
Online Access:http://psasir.upm.edu.my/id/eprint/5593/
http://psasir.upm.edu.my/id/eprint/5593/1/Adverse%20effects%20of%20imidocarb%20dipropionate.pdf
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author Abdullah, A. Salam
Abdul Rahman, Sheikh Omar
Desmond, Baggot J.
Saad, Mohd Zamri
author_facet Abdullah, A. Salam
Abdul Rahman, Sheikh Omar
Desmond, Baggot J.
Saad, Mohd Zamri
author_sort Abdullah, A. Salam
building UPM Institutional Repository
collection Online Access
description One of 13 healthy dogs used in a pharmacokinetic study of imidocarb dipropionate died due to difficulty in breathing, tachycardia, weakness and profuse diarrhoea. Autopsy findings showed marked pulmonary congestion and oedema. Kidneys were grossly enlarged and markedly congested with extensive haemorrhage in the cortex and medulla. Marked tubulonephrosis was also exhibited microscopically. Liver and spleen were moderately enlarged and congested. The adverse effects of imidocarb may be due to excessive acetylcholine action.
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publishDate 1984
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spelling upm-55932015-12-10T02:47:15Z http://psasir.upm.edu.my/id/eprint/5593/ Adverse effects of imidocarb dipropionate (Imizol) in a dog Abdullah, A. Salam Abdul Rahman, Sheikh Omar Desmond, Baggot J. Saad, Mohd Zamri One of 13 healthy dogs used in a pharmacokinetic study of imidocarb dipropionate died due to difficulty in breathing, tachycardia, weakness and profuse diarrhoea. Autopsy findings showed marked pulmonary congestion and oedema. Kidneys were grossly enlarged and markedly congested with extensive haemorrhage in the cortex and medulla. Marked tubulonephrosis was also exhibited microscopically. Liver and spleen were moderately enlarged and congested. The adverse effects of imidocarb may be due to excessive acetylcholine action. Kluwer Academic Publishers 1984 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/5593/1/Adverse%20effects%20of%20imidocarb%20dipropionate.pdf Abdullah, A. Salam and Abdul Rahman, Sheikh Omar and Desmond, Baggot J. and Saad, Mohd Zamri (1984) Adverse effects of imidocarb dipropionate (Imizol) in a dog. Veterinary Research Communications, 8 (1). pp. 55-59. ISSN 0165-7380; ESSN: 1573-7446 10.1007/BF02214695
spellingShingle Abdullah, A. Salam
Abdul Rahman, Sheikh Omar
Desmond, Baggot J.
Saad, Mohd Zamri
Adverse effects of imidocarb dipropionate (Imizol) in a dog
title Adverse effects of imidocarb dipropionate (Imizol) in a dog
title_full Adverse effects of imidocarb dipropionate (Imizol) in a dog
title_fullStr Adverse effects of imidocarb dipropionate (Imizol) in a dog
title_full_unstemmed Adverse effects of imidocarb dipropionate (Imizol) in a dog
title_short Adverse effects of imidocarb dipropionate (Imizol) in a dog
title_sort adverse effects of imidocarb dipropionate (imizol) in a dog
url http://psasir.upm.edu.my/id/eprint/5593/
http://psasir.upm.edu.my/id/eprint/5593/
http://psasir.upm.edu.my/id/eprint/5593/1/Adverse%20effects%20of%20imidocarb%20dipropionate.pdf