Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin
This study was aimed at examining the variations in the metabolite constituents of the different Ajwa grades and farm origins. It is also targeted at establishing the correlations between the metabolite contents and the grades and further to the nitric oxide (NO) inhibitory activity. Identification...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/55541/ http://psasir.upm.edu.my/id/eprint/55541/1/Discrimination%20and%20Nitric%20Oxide%20Inhibitory%20Activity%20Correlation%20of%20Ajwa%20Dates%20from%20Different%20Grades%20and%20Origin.pdf |
| _version_ | 1848852830916444160 |
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| author | Abdul Hamid, Nur Ashikin Mediani, Ahmed Maulidiani, M. Abas, Faridah Ismail, Intan Safinar Shaari, Khozirah Lajis, Nordin |
| author_facet | Abdul Hamid, Nur Ashikin Mediani, Ahmed Maulidiani, M. Abas, Faridah Ismail, Intan Safinar Shaari, Khozirah Lajis, Nordin |
| author_sort | Abdul Hamid, Nur Ashikin |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This study was aimed at examining the variations in the metabolite constituents of the different Ajwa grades and farm origins. It is also targeted at establishing the correlations between the metabolite contents and the grades and further to the nitric oxide (NO) inhibitory activity. Identification of the metabolites was generated using ¹H-NMR spectroscopy metabolomics analyses utilizing multivariate methods. The NO inhibitory activity was determined using a Griess assay. Multivariate data analysis, for both supervised and unsupervised approaches, showed clusters among different grades of Ajwa dates obtained from different farms. The compounds that contribute towards the observed separation between Ajwa samples were suggested to be phenolic compounds, ascorbic acid and phenylalanine. Ajwa dates were shown to have different metabolite compositions and exhibited a wide range of NO inhibitory activity. It is also revealed that Ajwa Grade 1 from the al-Aliah farm exhibited more than 90% NO inhibitory activity compared to the other grades and origins. Phenolic compounds were among the compounds that played a role towards the greater capacity of NO inhibitory activity shown by Ajwa Grade 1 from the al-Aliah farm. |
| first_indexed | 2025-11-15T10:44:19Z |
| format | Article |
| id | upm-55541 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:44:19Z |
| publishDate | 2016 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-555412017-08-14T10:41:10Z http://psasir.upm.edu.my/id/eprint/55541/ Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin Abdul Hamid, Nur Ashikin Mediani, Ahmed Maulidiani, M. Abas, Faridah Ismail, Intan Safinar Shaari, Khozirah Lajis, Nordin This study was aimed at examining the variations in the metabolite constituents of the different Ajwa grades and farm origins. It is also targeted at establishing the correlations between the metabolite contents and the grades and further to the nitric oxide (NO) inhibitory activity. Identification of the metabolites was generated using ¹H-NMR spectroscopy metabolomics analyses utilizing multivariate methods. The NO inhibitory activity was determined using a Griess assay. Multivariate data analysis, for both supervised and unsupervised approaches, showed clusters among different grades of Ajwa dates obtained from different farms. The compounds that contribute towards the observed separation between Ajwa samples were suggested to be phenolic compounds, ascorbic acid and phenylalanine. Ajwa dates were shown to have different metabolite compositions and exhibited a wide range of NO inhibitory activity. It is also revealed that Ajwa Grade 1 from the al-Aliah farm exhibited more than 90% NO inhibitory activity compared to the other grades and origins. Phenolic compounds were among the compounds that played a role towards the greater capacity of NO inhibitory activity shown by Ajwa Grade 1 from the al-Aliah farm. MDPI 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/55541/1/Discrimination%20and%20Nitric%20Oxide%20Inhibitory%20Activity%20Correlation%20of%20Ajwa%20Dates%20from%20Different%20Grades%20and%20Origin.pdf Abdul Hamid, Nur Ashikin and Mediani, Ahmed and Maulidiani, M. and Abas, Faridah and Ismail, Intan Safinar and Shaari, Khozirah and Lajis, Nordin (2016) Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin. Molecules, 21 (11). pp. 1-14. ISSN 1420-3049 http://www.mdpi.com/1420-3049/21/11/1423 10.3390/molecules21111423 |
| spellingShingle | Abdul Hamid, Nur Ashikin Mediani, Ahmed Maulidiani, M. Abas, Faridah Ismail, Intan Safinar Shaari, Khozirah Lajis, Nordin Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin |
| title | Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin |
| title_full | Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin |
| title_fullStr | Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin |
| title_full_unstemmed | Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin |
| title_short | Discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin |
| title_sort | discrimination and nitric oxide inhibitory activity correlation of ajwa dates from different grades and origin |
| url | http://psasir.upm.edu.my/id/eprint/55541/ http://psasir.upm.edu.my/id/eprint/55541/ http://psasir.upm.edu.my/id/eprint/55541/ http://psasir.upm.edu.my/id/eprint/55541/1/Discrimination%20and%20Nitric%20Oxide%20Inhibitory%20Activity%20Correlation%20of%20Ajwa%20Dates%20from%20Different%20Grades%20and%20Origin.pdf |