Detection of phenazines from UPMP3 strain of Pseudomonas aeruginosa and its antagonistic effects against Ganoderma boninense

To identify the phenazine antibiotics from the selected UPMP3 strain of Pseudomonas aeruginosa and assessment of its antagonistic activity of Ganoderma boninense, three antibiotics phenazine (PHZ), phenazine-l-carboxylic acid (PCA) and pyocyanin (PYO) were extracted from the bacterial fermented brot...

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Main Authors: Parvin, Waheeda, Othman, Radziah, Jaafar, Hawa, Wong, Mui-Yun
Format: Article
Language:English
Published: Friends Science Publishers 2016
Online Access:http://psasir.upm.edu.my/id/eprint/55461/
http://psasir.upm.edu.my/id/eprint/55461/1/Detection%20of%20Phenazines.pdf
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author Parvin, Waheeda
Othman, Radziah
Jaafar, Hawa
Wong, Mui-Yun
author_facet Parvin, Waheeda
Othman, Radziah
Jaafar, Hawa
Wong, Mui-Yun
author_sort Parvin, Waheeda
building UPM Institutional Repository
collection Online Access
description To identify the phenazine antibiotics from the selected UPMP3 strain of Pseudomonas aeruginosa and assessment of its antagonistic activity of Ganoderma boninense, three antibiotics phenazine (PHZ), phenazine-l-carboxylic acid (PCA) and pyocyanin (PYO) were extracted from the bacterial fermented broth using benzene and chloroform and detected through High-performance liquid chromatography (HPLC). The effects of three antibiotics on suppressing mycelial growth of G. boninense were assayed. The maximum amount of PHZ, PCA and PYO were recorded as 1.36, 9.62 and 15.48 μg/mL, respectively and showed in vitro antagonistic activity against G. boninense. Phenazine was found to be more effective than PCA and PYO to inhibit the mycelial growth of G. boninense. It was 100% for PHZ at 1.0 mg/mL, while 78.61% for PCA and 91.87% for PYO after 7 days of incubation. Phenazine, PCA and PYO were identified as first time from oil palm rhizospheric UPMP3 strain of P. aeruginosa. The results indicated that the identified PHZ, PCA and PYO compound had good antifungal activity against G. boninense, however the PHZ can be developed as an ideal biofungicide for the control basal stem rot disease of oil palm and helps to overcome the concerns about the residual effects of synthetic fungicides.
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spelling upm-554612017-09-14T09:52:53Z http://psasir.upm.edu.my/id/eprint/55461/ Detection of phenazines from UPMP3 strain of Pseudomonas aeruginosa and its antagonistic effects against Ganoderma boninense Parvin, Waheeda Othman, Radziah Jaafar, Hawa Wong, Mui-Yun To identify the phenazine antibiotics from the selected UPMP3 strain of Pseudomonas aeruginosa and assessment of its antagonistic activity of Ganoderma boninense, three antibiotics phenazine (PHZ), phenazine-l-carboxylic acid (PCA) and pyocyanin (PYO) were extracted from the bacterial fermented broth using benzene and chloroform and detected through High-performance liquid chromatography (HPLC). The effects of three antibiotics on suppressing mycelial growth of G. boninense were assayed. The maximum amount of PHZ, PCA and PYO were recorded as 1.36, 9.62 and 15.48 μg/mL, respectively and showed in vitro antagonistic activity against G. boninense. Phenazine was found to be more effective than PCA and PYO to inhibit the mycelial growth of G. boninense. It was 100% for PHZ at 1.0 mg/mL, while 78.61% for PCA and 91.87% for PYO after 7 days of incubation. Phenazine, PCA and PYO were identified as first time from oil palm rhizospheric UPMP3 strain of P. aeruginosa. The results indicated that the identified PHZ, PCA and PYO compound had good antifungal activity against G. boninense, however the PHZ can be developed as an ideal biofungicide for the control basal stem rot disease of oil palm and helps to overcome the concerns about the residual effects of synthetic fungicides. Friends Science Publishers 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/55461/1/Detection%20of%20Phenazines.pdf Parvin, Waheeda and Othman, Radziah and Jaafar, Hawa and Wong, Mui-Yun (2016) Detection of phenazines from UPMP3 strain of Pseudomonas aeruginosa and its antagonistic effects against Ganoderma boninense. International Journal of Agriculture and Biology, 18 (3). pp. 483-488. ISSN 1560-8530; ESSN: 1814-9596 10.17957/IJAB/15.0111
spellingShingle Parvin, Waheeda
Othman, Radziah
Jaafar, Hawa
Wong, Mui-Yun
Detection of phenazines from UPMP3 strain of Pseudomonas aeruginosa and its antagonistic effects against Ganoderma boninense
title Detection of phenazines from UPMP3 strain of Pseudomonas aeruginosa and its antagonistic effects against Ganoderma boninense
title_full Detection of phenazines from UPMP3 strain of Pseudomonas aeruginosa and its antagonistic effects against Ganoderma boninense
title_fullStr Detection of phenazines from UPMP3 strain of Pseudomonas aeruginosa and its antagonistic effects against Ganoderma boninense
title_full_unstemmed Detection of phenazines from UPMP3 strain of Pseudomonas aeruginosa and its antagonistic effects against Ganoderma boninense
title_short Detection of phenazines from UPMP3 strain of Pseudomonas aeruginosa and its antagonistic effects against Ganoderma boninense
title_sort detection of phenazines from upmp3 strain of pseudomonas aeruginosa and its antagonistic effects against ganoderma boninense
url http://psasir.upm.edu.my/id/eprint/55461/
http://psasir.upm.edu.my/id/eprint/55461/
http://psasir.upm.edu.my/id/eprint/55461/1/Detection%20of%20Phenazines.pdf