CYP2D6 genetic polymorphisms and phenotypes in different ethnicities of Malaysian breast cancer patients
The cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) is an enzyme that is predominantly involved in the metabolism of tamoxifen. Genetic polymorphisms of the CYP2D6 gene may contribute to inter-individual variability in tamoxifen metabolism, which leads to the differences in clinical r...
| Main Authors: | Fee, Wai Chin, Soon, Choy Chan, Abdul Rahman, Sabariah, , Sharifah Noor Akmal, Rosli, Rozita |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
John Wiley & Sons
2016
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/55412/ http://psasir.upm.edu.my/id/eprint/55412/1/CYP2D6%20genetic%20polymorphisms%20and%20phenotypes%20in%20different%20ethnicities%20of%20Malaysian%20breast%20cancer%20patients.pdf |
Similar Items
Genetic Polymorphism of CYP2D6 and MDR1 in breast cancer patients treated with tamoxifen
by: Mohamad, NI, et al.
Published: (2010)
by: Mohamad, NI, et al.
Published: (2010)
The Risk of Recurrence in Breast Cancer Patients Treated with Tamoxifen: Polymorphisms of CYP2D6 and ABCB1
by: Teh, L. K., et al.
Published: (2011)
by: Teh, L. K., et al.
Published: (2011)
Genetic Polymorphisms In The
CYP2A6: Implications For
Inter-Individual Differences
In Nicotine Metabolism
by: Musa, Nurfadhlina
Published: (2006)
by: Musa, Nurfadhlina
Published: (2006)
The role of pharmacogenetic variation in metoprolol CYP2D6 genotypes polymorphism
by: Wan Sulaiman, Wan Mohd. Azizi, et al.
Published: (2011)
by: Wan Sulaiman, Wan Mohd. Azizi, et al.
Published: (2011)
Population Pharmacokinetics Of Repaglinide In
Healthy Subjects And Genetic Polymorphisms Of
Cyp3a4 And Cyp2c8
by: Abu Bakar, Ruzilawati
Published: (2008)
by: Abu Bakar, Ruzilawati
Published: (2008)
Genetic polymorphisms of cyp3a4 and cyp2c8 in heal thy volunteers administered with
repaglinide
by: Gan Siew, Hua
Published: (2008)
by: Gan Siew, Hua
Published: (2008)
Identification and characterisation of single nucleotide polymorphisms in cytochrome P450 2D6 gene in Malaysian breast cancer patients
by: Chin, Fee Wai
Published: (2012)
by: Chin, Fee Wai
Published: (2012)
Influence Of Cyp2d6 And Drd2 Polymorphisms On Clinical Outcomes Of Patients With Schizophrenia
by: Zahari, Zalina
Published: (2009)
by: Zahari, Zalina
Published: (2009)
Genetic polymorphisms of CYP 3A4 & CYP2C8 in healthy volunteers title of project administered with repaglinide
by: Hua, Gan Siew
Published: (2008)
by: Hua, Gan Siew
Published: (2008)
The impact of CYP3A4 and CYP3A5 polymorphisms on anastrozole's pharmacokinetics and pharmacodynamics in post-menopausal breast cancer patients
by: Abubakar, Murtala Bello
Published: (2017)
by: Abubakar, Murtala Bello
Published: (2017)
CYP1A1 MspI polymorphism and cervical carcinoma risk in the multi-ethnic population of Malaysia: a case-control study
by: Tan, Yee Hock, et al.
Published: (2016)
by: Tan, Yee Hock, et al.
Published: (2016)
Contribution of CYP2E1 polymorphism to aging in the mechanical workshop workers
by: Eshkoor, Sima Ataollahi, et al.
Published: (2013)
by: Eshkoor, Sima Ataollahi, et al.
Published: (2013)
Identification and analysis of single nucleotide polymorphisms in matrix metallopeptidase 2 and 3 genes in Malaysian breast cancer patients
by: Chan, Soon Choy
Published: (2013)
by: Chan, Soon Choy
Published: (2013)
Cloning and expression of CYP2D6*1 and CYP2D6*10 and its application in vitro drug-herbs interaction studies
by: Lee, Wee Leng
Published: (2013)
by: Lee, Wee Leng
Published: (2013)
Genetic polymorphism of CYP2C9 in patients on warfarin therapy and the clinical relevance / Teh Lay Kek... [et al.]
by: Teh, Lay Kek, et al.
Published: (2007)
by: Teh, Lay Kek, et al.
Published: (2007)
Analysis of T344C genetic polymorphism of CYP11B2 gene in Malaysian end stage renal disease subjects.
by: Vasudevan, R., et al.
Published: (2011)
by: Vasudevan, R., et al.
Published: (2011)
A review on CYP11A1, CYP17A1, and CYP19A1 polymorphism studies: candidate susceptibility genes for polycystic ovary syndrome (PCOS) and infertility
by: Heidarzadehpilehrood, Roozbeh, et al.
Published: (2022)
by: Heidarzadehpilehrood, Roozbeh, et al.
Published: (2022)
Fas promoter -670 polymorphism and the risk of cervical cancer: a case-control study in multi-ethnic Malaysia
by: Tan, Yee Hock, et al.
Published: (2018)
by: Tan, Yee Hock, et al.
Published: (2018)
The influence of genetic polymorphisms of CYP3A on the pharmacokinetic variation and clinical outcomes of tacrolimus in a cohort of patients / Mohd Rahimi Muda
by: Muda, Mohd Rahimi
Published: (2014)
by: Muda, Mohd Rahimi
Published: (2014)
Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways
by: Zamanian, Mohammadreza, et al.
Published: (2016)
by: Zamanian, Mohammadreza, et al.
Published: (2016)
A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure
by: Ward, Natalie, et al.
Published: (2008)
by: Ward, Natalie, et al.
Published: (2008)
Prevalence of the CYP2D6*10 (C100T), *4 (G1846A), and *14 (G1758A) alleles among Iranians of different ethnicities
by: Bagheri, Ali, et al.
Published: (2015)
by: Bagheri, Ali, et al.
Published: (2015)
CYP2C9 polymorphism: prevalence in healthy and warfarin-treated Malay and Chinese in Malaysia
by: Ngow, Harris Abdullah, et al.
Published: (2009)
by: Ngow, Harris Abdullah, et al.
Published: (2009)
Risk factors and genetic polymorphisms of GSTM1, GSTT1 and CYP1A1 in development of oral cancer in an indonesian population / Rahmi Amtha
by: Amtha, Rahmi
Published: (2007)
by: Amtha, Rahmi
Published: (2007)
A CYP26B1 polymorphism enhances retinoic acid catabolism and may aggravate atherosclerosis.
by: Krivospitskaya, O., et al.
Published: (2012)
by: Krivospitskaya, O., et al.
Published: (2012)
Serotonin transporter polymorphisms and clinical response to sertraline across ethnicities
by: Ng, Chee Hong, et al.
Published: (2006)
by: Ng, Chee Hong, et al.
Published: (2006)
Metbod Development of Allele Specific PCR Assay for CYP2B6
by: Mohd Iqbal, Zulkafli
Published: (2009)
by: Mohd Iqbal, Zulkafli
Published: (2009)
In vitro study of modulatory effects of Strobilanthes crispus extracts on human cDNA-expressed cytochrome P450 2A6 (CYP2A6) and CYP3A4
by: pan, Yan, et al.
Published: (2016)
by: pan, Yan, et al.
Published: (2016)
Influence of ORM1, PXR, CAR, CYP3A4 and CYP3A5 gene polymorphisms in mediating susceptibility risk to chronic myeloid leukaemia and response to imatinib mesylate therapy
by: Maddin, Najlaa
Published: (2017)
by: Maddin, Najlaa
Published: (2017)
The implication of the polymorphism of COX-1, UGT1A6, and CYP2C9 among cardiovascular disease (CVD) patients treated with aspirin / Nur Jalinna Abdul Jalil
by: Abdul Jalil, Nur Jalinna
Published: (2014)
by: Abdul Jalil, Nur Jalinna
Published: (2014)
Genetic polymorphisms of endothelial marker, connexin and acyl-CoA genes among ethnic Malay subjects with essential hypertension
by: Salim, Elnaz
Published: (2020)
by: Salim, Elnaz
Published: (2020)
Influence of polycyclic aromatic hydrocarbon and genetic polymorphisms (cyp1a1, gstm1, gstt1) on pyrene metabolite and dna damage among children in the Klang Valley, Malaysia
by: Hisamuddin, Nur Hazirah
Published: (2022)
by: Hisamuddin, Nur Hazirah
Published: (2022)
Phenotypic characterization of breast cancer: the role of CDC42
by: Chrysanthou, Eleni, et al.
Published: (2017)
by: Chrysanthou, Eleni, et al.
Published: (2017)
Phenotypic and molecular characterisation of breast ductal carcinoma in situ
by: Abdelaziz, Islam Mohammed Samy Miligy
Published: (2019)
by: Abdelaziz, Islam Mohammed Samy Miligy
Published: (2019)
High occurrence of CYP3A5 variants among breast cancer and organ transplant patients
by: Ismail, S, et al.
Published: (2010)
by: Ismail, S, et al.
Published: (2010)
An autosomal glucose-6-phosphate dehydrogenase (hexose-6-phosphate dehydrogenase) polymorphism in human saliva
by: Tan, Soon Guan, et al.
Published: (1976)
by: Tan, Soon Guan, et al.
Published: (1976)
Hla Polymorphism In Malay Sub-Ethnic Groups In Peninsular Malaysia.
by: Atan, Edinur Hisham
Published: (2009)
by: Atan, Edinur Hisham
Published: (2009)
Prevalence of the UGT1A1*6 (c.211G>A) polymorphism and irinotecan toxicity in Iranian populations of different ethnicities
by: Shakibi, Reyhaneh, et al.
Published: (2015)
by: Shakibi, Reyhaneh, et al.
Published: (2015)
Does genetic polymorphisms affect health?
by: Ismail, Patimah
Published: (2011)
by: Ismail, Patimah
Published: (2011)
Red cell glyoxalase I and placental soluble aconitase polymorphisms in the three major ethnic groups of Malaysia
by: Teng, Yao Sheng, et al.
Published: (1978)
by: Teng, Yao Sheng, et al.
Published: (1978)
Similar Items
-
Genetic Polymorphism of CYP2D6 and MDR1 in breast cancer patients treated with tamoxifen
by: Mohamad, NI, et al.
Published: (2010) -
The Risk of Recurrence in Breast Cancer Patients Treated with Tamoxifen: Polymorphisms of CYP2D6 and ABCB1
by: Teh, L. K., et al.
Published: (2011) -
Genetic Polymorphisms In The
CYP2A6: Implications For
Inter-Individual Differences
In Nicotine Metabolism
by: Musa, Nurfadhlina
Published: (2006) -
The role of pharmacogenetic variation in metoprolol CYP2D6 genotypes polymorphism
by: Wan Sulaiman, Wan Mohd. Azizi, et al.
Published: (2011) -
Population Pharmacokinetics Of Repaglinide In
Healthy Subjects And Genetic Polymorphisms Of
Cyp3a4 And Cyp2c8
by: Abu Bakar, Ruzilawati
Published: (2008)