Clausenidin from Clausena excavata induces apoptosis in hepG2 cells via the mitochondrial pathway
Ethnopharmacological relevance: Clausena excavata Burm.f. is used locally in folk medicine for the treatment of cancer in South East Asia. Aim of the study: To determine the mechanism of action of pure clausenidin crystals in the induction of hepatocellular carcinoma (hepG2) cells apoptosis. Mater...
| Main Authors: | Waziri, Peter M., Abdullah, Rasedee, Swee, Keong Yeap, Omar, Abdul Rahman, Abdul, Ahmad Bustamam, Kassim, Nur Kartinee, Malami, Ibrahim, Karunakaran, Thiruventhan, Imam, Mustapha Umar |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/55287/ http://psasir.upm.edu.my/id/eprint/55287/1/Clausenidin%20from%20Clausena%20excavata%20induces%20apoptosis%20in%20hepG2%20cells%20via%20the%20.pdf |
Similar Items
Characterization and cytotoxicity of clausenidin from Clausena excavata Burm f. and its effects on cell cycle regulation and apoptosis of liver (hepg2) and colon (ht29) cancer cell lines
by: Waziri, Peter Maitalata
Published: (2017)
by: Waziri, Peter Maitalata
Published: (2017)
Clausenidin induces caspase-dependent apoptosis in colon cancer
by: Waziri, Peter M., et al.
Published: (2016)
by: Waziri, Peter M., et al.
Published: (2016)
Cytotoxic constituents of Clausena excavata
by: Mohd Shariff, Nurul Waznah, et al.
Published: (2011)
by: Mohd Shariff, Nurul Waznah, et al.
Published: (2011)
Cytotoxicty of zerumbone against liver cancer cell lines (HepG2) via apoptosis activity
by: Abdul Samad, Nozlena, et al.
Published: (2014)
by: Abdul Samad, Nozlena, et al.
Published: (2014)
Chemical Constituents And Bioactivities Of Clausena Excavata
by: Muhamad Sharif, Nurul Waznah
Published: (2009)
by: Muhamad Sharif, Nurul Waznah
Published: (2009)
Anti-inflammatory evidence of Clausena excavata in excision wound-induced rats
by: Albaayit, Shaymaa Fadhel Abbas, et al.
Published: (2016)
by: Albaayit, Shaymaa Fadhel Abbas, et al.
Published: (2016)
Evaluation of antioxidant activity and acute toxicity of Clausena excavata leaves extract
by: Albaayit, Shaymaa Fadhel Abbas, et al.
Published: (2014)
by: Albaayit, Shaymaa Fadhel Abbas, et al.
Published: (2014)
Chemical Constituents and Biological Activity of Clausena Excavata (Rutaceae)
by: Lim, Gin Keat
Published: (2005)
by: Lim, Gin Keat
Published: (2005)
A new cytotoxic carbazole alkaloid from Clausena excavata
by: Yap, Taufiq Yun Hin, et al.
Published: (2007)
by: Yap, Taufiq Yun Hin, et al.
Published: (2007)
Nutrient Composition, Antioxidant Andantiproliferative Properties Of Clausena Excavata Andmurraya Koenigii.
by: Wan Mohamad Zain, Wan Nor I'zzah
Published: (2005)
by: Wan Mohamad Zain, Wan Nor I'zzah
Published: (2005)
Analysis of Flavonoids and Essential Oils from Clausena Excavata and Their Medicinal Properties
by: Lim, Lay Sean
Published: (2004)
by: Lim, Lay Sean
Published: (2004)
Prophylactic effects of Clausena excavata Burum. f. leaf extract in ethanol-induced gastric ulcers
by: Albaayit, Shaymaa Fadhel Abbas, et al.
Published: (2016)
by: Albaayit, Shaymaa Fadhel Abbas, et al.
Published: (2016)
Zerumbone Exerts Antiproliferative Activity via Apoptosis on
HepG2 Cells
by: Syed Alwi, Sharifah Sakinah, et al.
Published: (2007)
by: Syed Alwi, Sharifah Sakinah, et al.
Published: (2007)
Chemical constituents and biological activities of Clausena excavata and some citrus species (Rutaceae)
by: Peh, Tian Hai
Published: (2001)
by: Peh, Tian Hai
Published: (2001)
Anti- enterococcus faecalis, cytotoxicity, phytotoxicity, and anticancer studies on Clausena excavata Burum. f. (Rutaceae) leaves
by: Albaayit, Shaymaa Fadhel Abbas, et al.
Published: (2021)
by: Albaayit, Shaymaa Fadhel Abbas, et al.
Published: (2021)
Selective cytotoxicity of goniothalamin against hepatoblastoma HepG2 cells.
by: Al-Qubaisi, Mothanna, et al.
Published: (2011)
by: Al-Qubaisi, Mothanna, et al.
Published: (2011)
Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53
by: Zakaria, Yusmazura, et al.
Published: (2009)
by: Zakaria, Yusmazura, et al.
Published: (2009)
A new cytotoxic carbazole alkaloid isolated from the stem
bark of Malaysian Clausena excavata
by: Peh, Tian Hai, et al.
Published: (2013)
by: Peh, Tian Hai, et al.
Published: (2013)
Effect of ximenynic acid on cell cycle arrest and apoptosis and COX-1 in HepG2 cells
by: Cai, F., et al.
Published: (2016)
by: Cai, F., et al.
Published: (2016)
Chemical constituents and biological activities of two rutaceous plants : Clausena excavata Burm. and Evodia malayana Ridl.
by: Oktima, Winda
Published: (2013)
by: Oktima, Winda
Published: (2013)
Garcinia Dulcis fruit extract induced Cytotoxicity and Apoptosis in HepG2 liver cancer cell line
by: Abu Bakar, Mohd Fadzelly, et al.
Published: (2015)
by: Abu Bakar, Mohd Fadzelly, et al.
Published: (2015)
Cytotoxic Effect of Girinimbine on HepG2 Cells
by: Mohan, Suvita Syam
Published: (2011)
by: Mohan, Suvita Syam
Published: (2011)
Anatomy and histochemistry of structures producing aroma in leaves of Sygyzium aromaticum (L.) Merr. and Clausena excavata Burm. f.
by: Qamaruz Zaman, Faridah, et al.
Published: (2018)
by: Qamaruz Zaman, Faridah, et al.
Published: (2018)
Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cellsthrough the intrinsic pathway with involvement of NF-kB signalling andG0/G1 cell cycle arrest : a bioassay-guided approach
by: Arbab, Ismail Adam, et al.
Published: (2013)
by: Arbab, Ismail Adam, et al.
Published: (2013)
Artonin E induces p53-independent g1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cell
by: Etti, Imaobong Christopher, et al.
Published: (2017)
by: Etti, Imaobong Christopher, et al.
Published: (2017)
Wound healing and gastroprotective effects of Clausena excavata leaves extract by modulating inflammation and oxidative stress / Shaymaa Fadhel Abbas Albaayit
by: Shaymaa Fadhel , Abbas Albaayit
Published: (2016)
by: Shaymaa Fadhel , Abbas Albaayit
Published: (2016)
Regulation of p53-, Bcl-2- and Caspase-dependent Signaling Pathway in Xanthorrhizol-induced Apoptosis of HepG2 Hepatoma Cells
by: Tri Handayani,, et al.
Published: (2007)
by: Tri Handayani,, et al.
Published: (2007)
Antioxidant behaviour of carotenoids highly accumulated in HepG2 cells
by: Jaswir, Irwandi, et al.
Published: (2012)
by: Jaswir, Irwandi, et al.
Published: (2012)
Induction of apoptosis by gluconasturtiin-isothiocyanate (GNST-ITC) in human hepatocarcinoma HepG2 cells and human breast adenocarcinoma MCF-7 cells
by: Arumugam, Asvinidevi, et al.
Published: (2020)
by: Arumugam, Asvinidevi, et al.
Published: (2020)
Adverse effects of anti-tuberculosis drugs on HepG2 cell
bioenergetics
by: Elmorsy, E., et al.
Published: (2016)
by: Elmorsy, E., et al.
Published: (2016)
Gamma-tocotrienol alters protein expression of HepG2 cell line
by: Farahani ARS,, et al.
Published: (2008)
by: Farahani ARS,, et al.
Published: (2008)
Suppression effect of eurycomanone on the growth of HepG2
tumour transplanted in mice
by: Zakaria, Yusmazura
Published: (2011)
by: Zakaria, Yusmazura
Published: (2011)
Zerumbone induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in Jurkat cell line
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)
Effects of thymoquinone and thymoquinone-loaded nanostructured lipid carrier on hepatocellular carcinoma cell models, Hep3B and HepG2
by: Haron, Aminah Suhaila
Published: (2017)
by: Haron, Aminah Suhaila
Published: (2017)
Cytotoxicity of Clinacanthus Nutans Extracts on Human Hepatoma (HepG2) Cell Line
by: Hazrulrizawati, Hamid, et al.
Published: (2016)
by: Hazrulrizawati, Hamid, et al.
Published: (2016)
The growth suppressing effects of Girinimbine on Hepg2 involve induction of apoptosis and cell cycle arrest.
by: Syam, Suvitha, et al.
Published: (2011)
by: Syam, Suvitha, et al.
Published: (2011)
Role of oxidative stress in antituberculous drugs (individuals and combined) cytotoxicity in HepG2 cells
by: Elmorsy, Ekramy, et al.
Published: (2016)
by: Elmorsy, Ekramy, et al.
Published: (2016)
Vanillin rich fraction regulates LDLR and HMGCR gene expression in HepG2 cells.
by: Ismail, Maznah, et al.
Published: (2010)
by: Ismail, Maznah, et al.
Published: (2010)
Cytotoxic effects of conjugated linoleic acids on human hepatoma cancer cells (HepG2)
by: Melaku, Achenef, et al.
Published: (2012)
by: Melaku, Achenef, et al.
Published: (2012)
Production and characterization of phycobiliproteins from cyanobacteria and their effects on HepG2 cancer cell lines
by: Begium, Hasina
Published: (2014)
by: Begium, Hasina
Published: (2014)
Similar Items
-
Characterization and cytotoxicity of clausenidin from Clausena excavata Burm f. and its effects on cell cycle regulation and apoptosis of liver (hepg2) and colon (ht29) cancer cell lines
by: Waziri, Peter Maitalata
Published: (2017) -
Clausenidin induces caspase-dependent apoptosis in colon cancer
by: Waziri, Peter M., et al.
Published: (2016) -
Cytotoxic constituents of Clausena excavata
by: Mohd Shariff, Nurul Waznah, et al.
Published: (2011) -
Cytotoxicty of zerumbone against liver cancer cell lines (HepG2) via apoptosis activity
by: Abdul Samad, Nozlena, et al.
Published: (2014) -
Chemical Constituents And Bioactivities Of Clausena Excavata
by: Muhamad Sharif, Nurul Waznah
Published: (2009)