Characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical DNA biosensors
In this work, two different approaches to gold nanoparticles (AuNPs) have been explored for the modification of screen-printed electrode based on AuNPs and AuNPs stabilized with polylactic acid (PLA). The modified substrate has been characterized using UV-Vis spectroscopy, X-ray diffraction (XRD), t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Brazilian Society of Chemistry
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/55272/ http://psasir.upm.edu.my/id/eprint/55272/1/Characterization%20of%20polylactide-stabilized%20gold%20nanoparticles%20and%20its%20application%20in%20the%20.pdf |
| _version_ | 1848852758640197632 |
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| author | Nordin, Noordiana Yusof, Nor Azah Abdullah, Jaafar Radu, Son Hajian, Reza |
| author_facet | Nordin, Noordiana Yusof, Nor Azah Abdullah, Jaafar Radu, Son Hajian, Reza |
| author_sort | Nordin, Noordiana |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | In this work, two different approaches to gold nanoparticles (AuNPs) have been explored for the modification of screen-printed electrode based on AuNPs and AuNPs stabilized with polylactic acid (PLA). The modified substrate has been characterized using UV-Vis spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), field emission scanning electron microscopy (FESEM) and cyclic voltammetry. Both synthesized AuNPs were studied in terms of stability, sensitivity and reproducibility to enhance the sensing capability of modified electrodes. The PLA-stabilized AuNPs form strong structured nanoparticles and stabilize in aqueous solution. A larger active surface area (0.41 cm2) and lower charge transfer resistance (Rct) value were reported in the modification of sensing material with PLA-stabilized AuNPs, which resulted in enhancement of sensitivity. Therefore, AuNPs in PLA can be used as a potential alternative modifier for sensing chemicals and biomolecules in electrochemical sensors. |
| first_indexed | 2025-11-15T10:43:10Z |
| format | Article |
| id | upm-55272 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:43:10Z |
| publishDate | 2016 |
| publisher | Brazilian Society of Chemistry |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-552722018-08-15T09:01:39Z http://psasir.upm.edu.my/id/eprint/55272/ Characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical DNA biosensors Nordin, Noordiana Yusof, Nor Azah Abdullah, Jaafar Radu, Son Hajian, Reza In this work, two different approaches to gold nanoparticles (AuNPs) have been explored for the modification of screen-printed electrode based on AuNPs and AuNPs stabilized with polylactic acid (PLA). The modified substrate has been characterized using UV-Vis spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), field emission scanning electron microscopy (FESEM) and cyclic voltammetry. Both synthesized AuNPs were studied in terms of stability, sensitivity and reproducibility to enhance the sensing capability of modified electrodes. The PLA-stabilized AuNPs form strong structured nanoparticles and stabilize in aqueous solution. A larger active surface area (0.41 cm2) and lower charge transfer resistance (Rct) value were reported in the modification of sensing material with PLA-stabilized AuNPs, which resulted in enhancement of sensitivity. Therefore, AuNPs in PLA can be used as a potential alternative modifier for sensing chemicals and biomolecules in electrochemical sensors. Brazilian Society of Chemistry 2016-09 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/55272/1/Characterization%20of%20polylactide-stabilized%20gold%20nanoparticles%20and%20its%20application%20in%20the%20.pdf Nordin, Noordiana and Yusof, Nor Azah and Abdullah, Jaafar and Radu, Son and Hajian, Reza (2016) Characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical DNA biosensors. Journal of the Brazilian Chemical Society, 27 (9). pp. 679-1686. ISSN 0103-5053; ESSN: 1678-4790 10.5935/0103-5053.20160047 |
| spellingShingle | Nordin, Noordiana Yusof, Nor Azah Abdullah, Jaafar Radu, Son Hajian, Reza Characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical DNA biosensors |
| title | Characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical DNA biosensors |
| title_full | Characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical DNA biosensors |
| title_fullStr | Characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical DNA biosensors |
| title_full_unstemmed | Characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical DNA biosensors |
| title_short | Characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical DNA biosensors |
| title_sort | characterization of polylactide-stabilized gold nanoparticles and its application in the fabrication of electrochemical dna biosensors |
| url | http://psasir.upm.edu.my/id/eprint/55272/ http://psasir.upm.edu.my/id/eprint/55272/ http://psasir.upm.edu.my/id/eprint/55272/1/Characterization%20of%20polylactide-stabilized%20gold%20nanoparticles%20and%20its%20application%20in%20the%20.pdf |