Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica
Ipomoea aquatica Forsk is a green leafy vegetable that is a rich source of amino acids and vitamins. Antioxidant and α-glucosidase inhibitory activities of the hexane (IAHE) and methanol (IAME) fractions of the vegetable portion of I. aquatica were investigated. The IAME fraction exhibited a strong...
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ACG Publications
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/55090/ http://psasir.upm.edu.my/id/eprint/55090/1/Antioxidant%20and%20%CE%B1-glucosidase%20inhibitory%20activities%20of%20isolated%20compounds%20from%20ipomoea%20.pdf |
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| author | Lawal, Umar Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah |
| author_facet | Lawal, Umar Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah |
| author_sort | Lawal, Umar |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Ipomoea aquatica Forsk is a green leafy vegetable that is a rich source of amino acids and vitamins. Antioxidant and α-glucosidase inhibitory activities of the hexane (IAHE) and methanol (IAME) fractions of the vegetable portion of I. aquatica were investigated. The IAME fraction exhibited a strong scavenging effect of the 2,2-diphenyl-2-picryl hydrazyl (DPPH) free radicals, and this fraction contained the highest phenolic contents. Phytochemical investigation of the IAME fraction yielded three known compounds, namely 3,5-di-O-caffeoylquinic acid (1), 4,5-di-O-caffeoylquinic acid (2) and quercetin 3-O-β-D-glucoside (3). The structures were unambiguously elucidated based on 1D and 2D-NMR analyses (1H, 13C, COSY, HSQC, HMBC) and mass spectrometry data. Compound 3 was isolated for the first time from this plant. |
| first_indexed | 2025-11-15T10:42:24Z |
| format | Article |
| id | upm-55090 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:42:24Z |
| publishDate | 2016 |
| publisher | ACG Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-550902018-08-13T07:44:57Z http://psasir.upm.edu.my/id/eprint/55090/ Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica Lawal, Umar Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah Ipomoea aquatica Forsk is a green leafy vegetable that is a rich source of amino acids and vitamins. Antioxidant and α-glucosidase inhibitory activities of the hexane (IAHE) and methanol (IAME) fractions of the vegetable portion of I. aquatica were investigated. The IAME fraction exhibited a strong scavenging effect of the 2,2-diphenyl-2-picryl hydrazyl (DPPH) free radicals, and this fraction contained the highest phenolic contents. Phytochemical investigation of the IAME fraction yielded three known compounds, namely 3,5-di-O-caffeoylquinic acid (1), 4,5-di-O-caffeoylquinic acid (2) and quercetin 3-O-β-D-glucoside (3). The structures were unambiguously elucidated based on 1D and 2D-NMR analyses (1H, 13C, COSY, HSQC, HMBC) and mass spectrometry data. Compound 3 was isolated for the first time from this plant. ACG Publications 2016 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/55090/1/Antioxidant%20and%20%CE%B1-glucosidase%20inhibitory%20activities%20of%20isolated%20compounds%20from%20ipomoea%20.pdf Lawal, Umar and Shaari, Khozirah and Ismail, Intan Safinar and Khatib, Alfi and Abas, Faridah (2016) Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica. Records of Natural Products, 10 (6). pp. 701-707. ISSN 1307-6167 |
| spellingShingle | Lawal, Umar Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica |
| title | Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica |
| title_full | Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica |
| title_fullStr | Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica |
| title_full_unstemmed | Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica |
| title_short | Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica |
| title_sort | antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica |
| url | http://psasir.upm.edu.my/id/eprint/55090/ http://psasir.upm.edu.my/id/eprint/55090/1/Antioxidant%20and%20%CE%B1-glucosidase%20inhibitory%20activities%20of%20isolated%20compounds%20from%20ipomoea%20.pdf |