Human mesenchymal stromal cells modulate T-cell immune response via transcriptomic regulation

QR Code

Human mesenchymal stromal cells modulate T-cell immune response via transcriptomic regulation

Background aims: Mesenchymal stromal cells (MSCs) have been identified as pan-immunosuppressant in various in vitro and in vivo inflammatory models. Although the immunosuppressive activity of MSCs has been explored in various contexts, the precise molecular signaling pathways that govern inhibitory...

Full description

Bibliographic Details
Main Authors:	Vellasamy, Shalini, Tong, Chih Kong, Azhar, Nur Atiqah, Kodiappan, Radha, Chan, Soon Choy, Veerakumarasivam, Abhi, Ramasamy, Rajesh
Format:	Article
Language:	English
Published:	Elsevier 2016
Subjects:	Cell-cycle arrest; Gene expression; Immunomodulation; Mesenchymal stromal cells; T cells
Online Access:	http://psasir.upm.edu.my/id/eprint/54461/ http://psasir.upm.edu.my/id/eprint/54461/1/Human%20mesenchymal%20stromal%20cells%20modulate%20T-cell%20immune%20response%20via%20transcriptomic%20regulation.pdf

Similar Items

Generation and characterisation of mesenchymal stem cells derived from human cartilage
by: Sandrasaigaran, Pratheep
Published: (2014)

Mesenchymal stem cell-mediated immunomodulation of microglia
by: Jose, Shinsmon
Published: (2013)

Mesenchymal stem cell and microglia crosstalk in an inflammatory paradigm
by: Rahmat, Muhammad Zul'atfi
Published: (2013)

Development of a topical therapeutic strategy using corneal derived mesenchymal stromal cells for the treatment of ocular surface disorders
by: Beeken, Lydia
Published: (2023)

Non-viral transfection of bone marrow-derived mesenchymal stem cell with human interferon-gamma gene and in vitro efficiency against chronic myeloid leukaemia cells
by: Liew, Lee Chuen
Published: (2013)

Immunomodulatory and gene expression characterisation of human mesenchymal stem cells derived from non-osteoarthritic and osteoarthritic cartilage
by: Al-Graittee, Satar Jabbar Rahi
Published: (2018)

Use of pectin for the spray delivery of mesenchymal stromal cells for brain injury
by: Nash, Amy Louise
Published: (2023)

Phenotypic change and induction of cytokeratin expression during in vitro culture of corneal stromal cells
by: Sidney, Laura E., et al.
Published: (2015)

Generation and Characterisation of Mesenchymal Stem Cells Derived from Placenta and Adult Cardiac Tissue
by: Vellasamy, Shalini
Published: (2011)

Generation and Characterisation of Human Mesenchymal Stem Cells from Human Umbilical Cord
by: Tong, Chih Kong
Published: (2010)

Effect of culture medium on propagation and phenotype of corneal stroma-derived stem cells
by: Sidney, Laura E., et al.
Published: (2015)

Generation, propagation and characterization of second and full-term amniotic fluid-derived mesenchymal stem cell
by: Ghoraishizadeh, Peyman
Published: (2016)

Exploring the immunomodulatory effects of human mesenchymal stem cells on monocyte functions
by: Maqbool, Maryam
Published: (2016)

Senolytic and mitogenic activities of Moringa oleifera Lam. leaf extract on culture expanded and doxorubicin oxidative stress-induced umbilical cord mesenchymal stem cells
by: Adamu, Muhammad Umar
Published: (2022)

Differentiation of marrow stromal cells into photoreceptors in the rat eye
by: Kicic, Anthony, et al.
Published: (2003)

Anti-tumour efficacy of human mesenchymal stem cell expressing trail on lung cancer cell lines-derived cancer stem cell
by: Shaik M Fakiruddin, Shaik Ahmad Kamal
Published: (2021)

Generation and characterization of human cardiac resident and non-resident mesenchymal stem cell
by: Subramani, Baskar, et al.
Published: (2016)

Mitogenic activity of mesenchymal stem cells on hematopoietic stem cells via cellular analysis and gene expression
by: Mohadeseh, Hashem Boroojerdi
Published: (2015)

Dynamic surfaces for the study Of mesenchymal stem cell growth through adhesion regulation
by: Roberts, Jemma, et al.
Published: (2016)

Human rather than mouse mesenchymal stem cells in 3D co-culture models boost proliferative and migratory characteristics of colorectal cancer cells through paracrine signalling pathways, highlighting species disconnects
by: Lu, M.
Published: (2022)

A synthetic formulation, Dhanwantharam kashaya, delays senescence in stem cells
by: Warrier, S, et al.
Published: (2013)

Corneal keratocyte transition to mesenchymal stem cell phenotype and reversal using serum-free medium supplemented with FGF-2, TGF-ß3 and retinoic acid
by: Sidney, Laura E., et al.
Published: (2016)

In vitro study of various factors in isolation, expansion and differentiation of mesenchymal stem cells from human umbilical cord
by: Salehinejad, Parvin
Published: (2012)

Comparison of immunomodulatory factors produced by mesenchymal stem cells in multiple sclerosis patients and healthy controls
by: Thevathas, Sarah
Published: (2018)

Labeling of mesenchymal stem cells for MRI with single-cell sensitivity
by: Ariza de Schellenberger, Angela, et al.
Published: (2016)

Generation and characterisation of adipose tissue-and umbilical-cord-derived mesenchymal stem cells expressing trail apoptotic ligand
by: Shamsul Kamal, Aishah Amirah
Published: (2024)

A biomaterials approach to influence stem cell fate in injectable cell-based therapies
by: Amer, Mahetab H., et al.
Published: (2018)

Effects of inflammatory mediators on bone marrow mesenchymal stem cells
by: Marsh, Sarah A.
Published: (2019)

Development of an optimal xeno-free cGMP growth medium for the culture of corneal stroma-derived mesenchymal stem cells
by: Ekrem, Melis
Published: (2020)

Discovering novel immune-modulatory monosaccharides using high-throughput screening strategies
by: Alobaid, Meshal
Published: (2020)

Cellular and molecular mechanisms underlying extravasation of human Wharton’s jelly mesenchymal stem cells across fetal and adult endothelial cell monolayers
by: Ebrahim, Neven
Published: (2016)

The impact of stroma and ionising radiation on the plasticity of dendritic cells and macrophages
by: Malecka, Anna A.
Published: (2018)

The influence of stromal fibroblast on antigen-presenting cell function and alteration of their biology
by: Mohammad, Salaheddin
Published: (2022)

Magnetic targeting of stem cell therapies
by: Harrison, Richard P.
Published: (2016)

Analysis of the Ccr4-Not deadenylase complex: a biochemical and computational approach
by: Balacco, Dario Leonardo
Published: (2017)

Microcarriers with Complex Architectures Manufactured by Two-Photon Lithography for Mechanobiological Manipulation and Expansion of Mesenchymal Stem Cells
by: Hutchinson, Jason
Published: (2023)

Analysis of transcriptomic changes that occur following loss of DARPP-32 expression in breast cancer
by: Storr, Sarah
Published: (2022)

Comparative study of the biological properties of foetal and placental distal ends of human umbilical cord wharton's jelly mesenchymal stem cells
by: Yusoff, Zuraidah
Published: (2015)

Characterising the structural, functional and metabolomic changes occurring in human corneal cells due to Acanthamoeba castellanii secretome and amelioration of infection using cerium oxide nanoparticles
by: Alhazmi, Abdullah
Published: (2022)

Application of mesenchymal stem cells for therapeutic agent delivery in anti-tumor treatment
by: Chulpanoval, Daria S., et al.
Published: (2018)