Efficient double Suzuki cross-coupling reactions of 2,5-dibromo-3-hexylthiophene: anti-tumor, haemolytic, anti-thrombolytic and biofilm inhibition studies

Efficient double Suzuki cross-coupling reactions of 2,5-dibromo-3-hexylthiophene: anti-tumor, haemolytic, anti-thrombolytic and biofilm inhibition studies

The present study describes several novel 2,5-biaryl-3-hexylthiophene derivatives (3a-i) synthesized via a Pd(0)-catalyzed Suzuki cross-coupling reaction in moderate to good yields. The novel compounds were also analyzed for their anti-thrombolytic, haemolytic, and biofilm inhibition activities. In...

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Bibliographic Details
Main Authors: Ikram, Hafiz Mansoor, Rasool, Nasir, Zubair, Muhammad, Khan, Khalid Mohammed, Chotana, Ghayoor Abbas, Akhtar, Muhammad Nadeem, Abu, Nadiah, Alitheen, Noorjahan Banu, Elgorban, Abdallah Mohamed, Rana, Usman Ali
Format: Article
Language:English
Published: M D P I AG 2016
Subjects:
Suzuki cross-coupling reaction; 2,5-biaryl-3-hexylthiophene derivatives; Anti-tumor; Biofilm inhibition; Haemolysis; Anti-thrombolytic
Online Access:http://psasir.upm.edu.my/id/eprint/54128/
http://psasir.upm.edu.my/id/eprint/54128/1/Efficient%20double%20Suzuki.pdf

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