Effects of curcumin analogue, 2, 6-bis (2, 5-dimethoxybenzylidene) cyclohexanone (BDMC33) on the activities of drug-metabolizing enzymes in cultured Caco-2 cell model

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Effects of curcumin analogue, 2, 6-bis (2, 5-dimethoxybenzylidene) cyclohexanone (BDMC33) on the activities of drug-metabolizing enzymes in cultured Caco-2 cell model

Poor systemic delivery of curcumin outside the gut due to its rapid metabolism has severely limited its application to many chronic diseases. Previously, our research group synthesized curcumin analogues 2, 6-bis (2, 5-dimethoxybenzylidene) cyclohexanone (BDMC33) that has potent anti-inflammatory ac...

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Bibliographic Details
Main Authors:	Yakubu, Ndatsu, Ahmad, Syahida, Abas, Faridah, Mohammed, Umaru Alhassan
Format:	Article
Language:	English
Published:	International Journal of Pharmaceutical Sciences and Drug Research 2016
Subjects:	Caco-2 cells; Curcumin; Drug metabolizing enzymes; Glutathione-S-transferase; NADPH-cytochrome c reductase; Sulfotransferase; UDP-glucuronosyltransferase
Online Access:	http://psasir.upm.edu.my/id/eprint/54083/ http://psasir.upm.edu.my/id/eprint/54083/1/Effects%20of%20curcumin%20analogue.pdf

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