Small interfering RNA silencing of interleukin-6 in mesenchymal stromal cells inhibits multiple myeloma cell growth

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Small interfering RNA silencing of interleukin-6 in mesenchymal stromal cells inhibits multiple myeloma cell growth

Studies demonstrated that mesenchymal stromal cells (MSC) from bone marrow stroma produced high concentration of interleukin-6 (IL-6) that promoted multiple myeloma cell growth. In view of the failure of IL-6 monoclonal antibody therapy to demonstrate substantial clinical responses in early clinical...

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Bibliographic Details
Main Authors:	Teoh, Hoon Koon, Chong, Pei Pei, Abdullah, Maha, Sekawi, Zamberi, Tan, Geok Chin, Leong, Chooi Fun, Cheong, Soon Keng
Format:	Article
Language:	English
Published:	Elsevier 2016
Online Access:	http://psasir.upm.edu.my/id/eprint/53832/ http://psasir.upm.edu.my/id/eprint/53832/1/Small%20interfering%20RNA%20silencing%20of%20interleukin-6%20in%20mesenchymal%20stromal%20cells%20inhibits%20multiple%20myeloma%20cell%20growth.pdf

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