Pharmacological modulation of oncogenic Ras by natural products and their derivatives: renewed hope in the discovery of novel anti-Ras drugs

Pharmacological modulation of oncogenic Ras by natural products and their derivatives: renewed hope in the discovery of novel anti-Ras drugs

Oncogenic rat sarcoma (Ras) is linked to the most fatal cancers such as those of the pancreas, colon, and lung. Decades of research to discover an efficacious drug that can block oncogenic Ras signaling have yielded disappointing results; thus, Ras was considered “undruggable” until recently. Inhibi...

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Bibliographic Details
Main Authors: Quah, Shun Ying, Tan, Michelle Siying, Teh, Yuan Han, Stanslas, Johnson
Format: Conference or Workshop Item
Language:English
Published: Elsevier 2016
Online Access:http://psasir.upm.edu.my/id/eprint/53553/
http://psasir.upm.edu.my/id/eprint/53553/1/Pharmacological%20modulation%20of%20oncogenic%20Ras.pdf

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