Molecularly targeted therapies for asthma: current development, challenges and potential clinical translation

QR Code

Molecularly targeted therapies for asthma: current development, challenges and potential clinical translation

Extensive research into the therapeutics of asthma has yielded numerous effective interventions over the past few decades. However, adverse effects and ineffectiveness of most of these medications especially in the management of steroid resistant severe asthma necessitate the development of better m...

Full description

Bibliographic Details
Main Authors:	Sulaiman, Ibrahim, Lim, Jonathan Chee Woei, Soo, Hon Liong, Stanslas, Johnson
Format:	Article
Language:	English
Published:	Academic Press 2016
Online Access:	http://psasir.upm.edu.my/id/eprint/53331/ http://psasir.upm.edu.my/id/eprint/53331/1/Molecularly%20targeted%20therapies%20for%20asthma.pdf

Similar Items

Molecular and immunomodulatory actions of new antiasthmatic agents: exploring the diversity of biologics in Th2 endotype asthma
by: Okwuofu, Emmanuel Oshiogwe, et al.
Published: (2022)

Molecular targets in the discovery and development of novel antimetastatic agents: current progress and future prospects
by: Wong, Mei S., et al.
Published: (2013)

Advances and challenges in developing andrographolide and its analogues as cancer therapeutic agents
by: Soo, Hon Liong, et al.
Published: (2019)

Adaptive therapy to circumvent drug resistance to tyrosine kinase inhibitors in cancer: is it clinically relevant?
by: Hamdi, Amir Imran Faisal, et al.
Published: (2022)

Electronic monitoring devices in asthma: translating from study use into clinical practice
by: Adejumo, Ireti D.
Published: (2021)

Andrographolide restores healthy airway function in toluene diisocyanate-induced occupational mouse asthma model through upregulation of heam oxygenase-1 and activation of Akt/Nrf-2 dependent pathway
by: Sulaiman, Ibrahim, et al.
Published: (2017)

Economic Evaluation Of Respiratory Medication Therapy Adherence Clinic (Rmtac) On Asthma Patients In Malaysia
by: Yong, Yee Vern
Published: (2016)

Molecular Targets of Ascochlorin and Its Derivatives for Cancer Therapy
by: Min-Wen, J., et al.
Published: (2017)

Predicting response to Azithromycin therapy in asthma
by: Slater, Mariel
Published: (2015)

Andrographolide as a template in the synthesis of new anticancer agents with potentially novel molecular targets
by: Stanslas, Johnson, et al.
Published: (2010)

The impact of azithromycin therapy on the airway microbiota in asthma
by: Slater, Mariel, et al.
Published: (2014)

Pancreatic cancer treatment with targeted therapies: are we there yet
by: Nwaefulu, O. Ngozi, et al.
Published: (2022)

Nanomedicines for cancer therapy: current status, challenges and future prospects
by: Bor, Gizem, et al.
Published: (2019)

Current and emerging therapies for corneal infection: a clinical and laboratory study
by: Ting, Darren Shu Jeng
Published: (2022)

Transcranial Direct Current Stimulation for tinnitus: towards an improved understanding to facilitate clinical translation
by: Labree, Bas
Published: (2024)

Azithromycin for Acute Exacerbations of Asthma: the AZALEA randomized clinical trial
by: Johnson, Sebastian L., et al.
Published: (2016)

Identification of Epithelial Phospholipase A2 Receptor 1 as a Potential Target in Asthma
by: Nolin, J., et al.
Published: (2016)

Step 4: stick or twist? A review of asthma therapy
by: Slater, Mariel G., et al.
Published: (2016)

Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy
by: Hay, Jodie F., et al.
Published: (2017)

Defining the relationship between clinical and immunological features of asthma
by: Al Zahrani, Yousef
Published: (2019)

Translating childhood brain tumour research into clinical practice: the experience of molecular classification and diagnostics
by: Ritzmann, Timothy A., et al.
Published: (2018)

Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies
by: Shanmugam, M., et al.
Published: (2013)

Implementing patient counselling using pictorial personalised asthma action plan in government primary care clinics in Malaysia: challenges and potential solutions
by: Shariff Ghazali, Sazlina
Published: (2025)

3, 19-diacetyl-14-deoxy-11,12-didehydroandrographolide (srs27) antagonises inflammatory response and oxidative stress in in vitro and in vivo asthma models
by: Lim, Chee Woei
Published: (2014)

Paediatric asthma clinical pathway: Impact on cost and quality of care
by: Md. Sharif, Shakirah, et al.
Published: (2019)

Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma
by: Matthey, Michaela, et al.
Published: (2017)

Novel oral targeted therapies in inflammatory bowel disease
by: White, Jonathan Richard, et al.
Published: (2018)

Editorial: Current drug targets
by: Sulaiman, Ahmad Hatim, et al.
Published: (2019)

A review of standard pharmacological therapy for adult asthma - Steps 1 to 5
by: Patel, Mitesh Dilipkumar Kantilal, et al.
Published: (2015)

Organizational Leadership Development in Malaysia: Current Practices, Challenges and Future Potentials
by: Victoria, Jonathan, et al.
Published: (2017)

Magnetic targeting of stem cell therapies
by: Harrison, Richard P.
Published: (2016)

Molecular targets and anti-cancer potential of escin
by: Cheong, D., et al.
Published: (2018)

Novel, synergistic antifungal combinations that target translation fidelity
by: Moreno-Martinez, Elena, et al.
Published: (2015)

IDENTIFYING A NOVEL THERAPEUTIC STRATEGY FOR ASTHMA: TARGETING AIRWAY EPITHELIAL CELL RESTITUTION
by: Iosifidis, T., et al.
Published: (2017)

Targeting phosphoinositide 3-kinase pathways in pancreatic cancer - from molecular signalling to clinical trials
by: Falasca, Marco, et al.
Published: (2011)

Translating impoliteness - literature review, translation challenges, and translation strategies in cross-cultural communication
by: Yang, Wei, et al.
Published: (2025)

Biomarkers in AD: current state of translational research
by: Mohamed, Wael Mohamed Yousef
Published: (2018)

The Cellular and Molecular Basis of Translational Immunometabolism
by: Norata, Giuseppe, et al.
Published: (2015)

Electronic monitoring devices: necessary steps for their successful integration with current asthma care
by: Howard, Sam
Published: (2017)

Short-acting β-agonist use as a marker of current asthma control
by: Patel, Mitesh, et al.
Published: (2013)