ZnO-Ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects

In this paper, a novel green method for fabrication of zinc oxide-silver (ZnO-Ag) core-shell nanocomposite using essential oil of ginger (EO-G) is reported. The EO-G played two significant roles in the synthesis process: it could act as a reaction media for the formation of ZnO and reduce Ag+ to Ag0...

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Main Authors: Azizi, Susan, Mohamad, Rosfarizan, Abdul Rahim, Raha, Moghaddam, Amin Boroumand, Moniri, Mona, Ariff, Arbakariya, Saad, Wan Zuhainis, Namvab, Farideh
Format: Article
Language:English
Published: Elsevier 2016
Online Access:http://psasir.upm.edu.my/id/eprint/53271/
http://psasir.upm.edu.my/id/eprint/53271/1/123.pdf
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author Azizi, Susan
Mohamad, Rosfarizan
Abdul Rahim, Raha
Moghaddam, Amin Boroumand
Moniri, Mona
Ariff, Arbakariya
Saad, Wan Zuhainis
Namvab, Farideh
author_facet Azizi, Susan
Mohamad, Rosfarizan
Abdul Rahim, Raha
Moghaddam, Amin Boroumand
Moniri, Mona
Ariff, Arbakariya
Saad, Wan Zuhainis
Namvab, Farideh
author_sort Azizi, Susan
building UPM Institutional Repository
collection Online Access
description In this paper, a novel green method for fabrication of zinc oxide-silver (ZnO-Ag) core-shell nanocomposite using essential oil of ginger (EO-G) is reported. The EO-G played two significant roles in the synthesis process: it could act as a reaction media for the formation of ZnO and reduce Ag+ to Ag0. The bioformed ZnO-Ag nanocomposite was compared with pure biosynthesized ZnO-NPs and characterized by UV–vis spectroscopy, TEM, EDX, XRD and FTIR. The characterization results confirmed that Ag-NPs had been embedded in ZnO hexagonal nanoparticles. Six Gram positive and negative pathogens were used to investigate the antibacterial effects of these samples. Ag-doping improves the bactericidal activity of ZnO-NPs. In vitro cytotoxicity studies on Vero cells, a dose dependent toxicity with non-toxic effect of concentration below 100 μg/mL was shown for ZnO-Ag nanocomposite. The biosynthesized ZnO-Ag nanocomposites were found to be comparable to those obtained from the conventional methods using hazardous materials which can be an excellent alternative for the synthesis of ZnO-Ag using biomass.
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spelling upm-532712017-07-27T09:53:35Z http://psasir.upm.edu.my/id/eprint/53271/ ZnO-Ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects Azizi, Susan Mohamad, Rosfarizan Abdul Rahim, Raha Moghaddam, Amin Boroumand Moniri, Mona Ariff, Arbakariya Saad, Wan Zuhainis Namvab, Farideh In this paper, a novel green method for fabrication of zinc oxide-silver (ZnO-Ag) core-shell nanocomposite using essential oil of ginger (EO-G) is reported. The EO-G played two significant roles in the synthesis process: it could act as a reaction media for the formation of ZnO and reduce Ag+ to Ag0. The bioformed ZnO-Ag nanocomposite was compared with pure biosynthesized ZnO-NPs and characterized by UV–vis spectroscopy, TEM, EDX, XRD and FTIR. The characterization results confirmed that Ag-NPs had been embedded in ZnO hexagonal nanoparticles. Six Gram positive and negative pathogens were used to investigate the antibacterial effects of these samples. Ag-doping improves the bactericidal activity of ZnO-NPs. In vitro cytotoxicity studies on Vero cells, a dose dependent toxicity with non-toxic effect of concentration below 100 μg/mL was shown for ZnO-Ag nanocomposite. The biosynthesized ZnO-Ag nanocomposites were found to be comparable to those obtained from the conventional methods using hazardous materials which can be an excellent alternative for the synthesis of ZnO-Ag using biomass. Elsevier 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/53271/1/123.pdf Azizi, Susan and Mohamad, Rosfarizan and Abdul Rahim, Raha and Moghaddam, Amin Boroumand and Moniri, Mona and Ariff, Arbakariya and Saad, Wan Zuhainis and Namvab, Farideh (2016) ZnO-Ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects. Applied Surface Science, 384 (10). pp. 517-524. ISSN 0169-4332 http://www.elsevier.com/locate/apsusc 10.1016/j.apsusc.2016.05.052
spellingShingle Azizi, Susan
Mohamad, Rosfarizan
Abdul Rahim, Raha
Moghaddam, Amin Boroumand
Moniri, Mona
Ariff, Arbakariya
Saad, Wan Zuhainis
Namvab, Farideh
ZnO-Ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects
title ZnO-Ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects
title_full ZnO-Ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects
title_fullStr ZnO-Ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects
title_full_unstemmed ZnO-Ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects
title_short ZnO-Ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects
title_sort zno-ag core shell nanocomposite formed by green method using essential oil of wild ginger and their bactericidal and cytotoxic effects
url http://psasir.upm.edu.my/id/eprint/53271/
http://psasir.upm.edu.my/id/eprint/53271/
http://psasir.upm.edu.my/id/eprint/53271/
http://psasir.upm.edu.my/id/eprint/53271/1/123.pdf