Simulation of left-truncated and case-k interval censored survival data with time-varying covariates
This research focuses on simulation of left-truncated and case-k interval censored survival data from the log-normal model with a time-varying covariate. Left-truncated data usually arises in prevalence cohort study where randomly selected individuals from medical records may have contracted certain...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Institute for Mathematical Research, Universiti Putra Malaysia
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/52365/ http://psasir.upm.edu.my/id/eprint/52365/1/11.%20Thirunanthini.pdf |
| _version_ | 1848852085225816064 |
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| author | Manoharan, Thirunanthini Arasan, Jayanthi Midi, Habshah Adam, Mohd Bakri |
| author_facet | Manoharan, Thirunanthini Arasan, Jayanthi Midi, Habshah Adam, Mohd Bakri |
| author_sort | Manoharan, Thirunanthini |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This research focuses on simulation of left-truncated and case-k interval censored survival data from the log-normal model with a time-varying covariate. Left-truncated data usually arises in prevalence cohort study where randomly selected individuals from medical records may have contracted certain disease for some duration of time but are free from event of interest at time of entry into a survival study. In this research, we proposed a simulation methodology by fixing the percentage of truncation at 20% and 60% with the width of 4 months of inspection interval. The procedure was computationally demanding due to the presence of left-truncation and time-varying covariates. The suitability of the proposed method was assessed based on the bias, standard error and root mean square of the parameter estimates for the log-normal survival model. |
| first_indexed | 2025-11-15T10:32:28Z |
| format | Article |
| id | upm-52365 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:32:28Z |
| publishDate | 2016 |
| publisher | Institute for Mathematical Research, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-523652017-06-05T09:35:14Z http://psasir.upm.edu.my/id/eprint/52365/ Simulation of left-truncated and case-k interval censored survival data with time-varying covariates Manoharan, Thirunanthini Arasan, Jayanthi Midi, Habshah Adam, Mohd Bakri This research focuses on simulation of left-truncated and case-k interval censored survival data from the log-normal model with a time-varying covariate. Left-truncated data usually arises in prevalence cohort study where randomly selected individuals from medical records may have contracted certain disease for some duration of time but are free from event of interest at time of entry into a survival study. In this research, we proposed a simulation methodology by fixing the percentage of truncation at 20% and 60% with the width of 4 months of inspection interval. The procedure was computationally demanding due to the presence of left-truncation and time-varying covariates. The suitability of the proposed method was assessed based on the bias, standard error and root mean square of the parameter estimates for the log-normal survival model. Institute for Mathematical Research, Universiti Putra Malaysia 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/52365/1/11.%20Thirunanthini.pdf Manoharan, Thirunanthini and Arasan, Jayanthi and Midi, Habshah and Adam, Mohd Bakri (2016) Simulation of left-truncated and case-k interval censored survival data with time-varying covariates. Malaysian Journal of Mathematical Sciences, 10 (spec. Aug.). pp. 159-173. ISSN 1823-8343; ESSN: 2289-750X http://einspem.upm.edu.my/journal/fullpaper/vol10saugust/11.%20Thirunanthini.pdf |
| spellingShingle | Manoharan, Thirunanthini Arasan, Jayanthi Midi, Habshah Adam, Mohd Bakri Simulation of left-truncated and case-k interval censored survival data with time-varying covariates |
| title | Simulation of left-truncated and case-k interval censored survival data with time-varying covariates |
| title_full | Simulation of left-truncated and case-k interval censored survival data with time-varying covariates |
| title_fullStr | Simulation of left-truncated and case-k interval censored survival data with time-varying covariates |
| title_full_unstemmed | Simulation of left-truncated and case-k interval censored survival data with time-varying covariates |
| title_short | Simulation of left-truncated and case-k interval censored survival data with time-varying covariates |
| title_sort | simulation of left-truncated and case-k interval censored survival data with time-varying covariates |
| url | http://psasir.upm.edu.my/id/eprint/52365/ http://psasir.upm.edu.my/id/eprint/52365/ http://psasir.upm.edu.my/id/eprint/52365/1/11.%20Thirunanthini.pdf |