Bioassay-guided isolation of deoxypodophyllotoxin, the cytotoxic constituent of Juniperus chinensis

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Bioassay-guided isolation of deoxypodophyllotoxin, the cytotoxic constituent of Juniperus chinensis

The ethanol extract from the leaves of Juniperus chinensis was found to be cytotoxic towards HeLa cells. Bioassay-guided fractionation of the EtOAc soluble faction directed by the microtitration cytotoxic assay revealed that the cytotoxic compound was deoxypodophyllotoxin. All the tumour cell lines...

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Bibliographic Details
Main Authors:	Ali, Abdul Manaf, Ismail, Intan Safinar, Mohamed Mackeen, Muhammad Mukram, El-Sharkawy, Saleh Hassan, Takahata, Kyoya, Kanzaki, Hiroshi, Kawazu, Kazuyoshi
Format:	Article
Language:	English
Published:	Korean Society of Pharmacognosy 1998
Online Access:	http://psasir.upm.edu.my/id/eprint/51340/ http://psasir.upm.edu.my/id/eprint/51340/1/51340.pdf

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