Hyperchaos in acetylcholinesterase enzyme systems

Burst generation via a complex bifurcation scenario is discussed using a two compartments model of an enzyme system with substrate inhibition kinetics affected by the production of hydrogen ions accompanying the reaction (e.g. acetylcholinesterase enzyme system). Evidences are given to support the e...

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Main Authors: Ibrahim, Gamal, Elnashaie, Said Salah Eldin Hamed
Format: Article
Language:English
English
Published: Elsevier Science 1997
Online Access:http://psasir.upm.edu.my/id/eprint/51025/
http://psasir.upm.edu.my/id/eprint/51025/1/51025.pdf
http://psasir.upm.edu.my/id/eprint/51025/7/1-s2.0-S0960077996001415-main.pdf
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author Ibrahim, Gamal
Elnashaie, Said Salah Eldin Hamed
author_facet Ibrahim, Gamal
Elnashaie, Said Salah Eldin Hamed
author_sort Ibrahim, Gamal
building UPM Institutional Repository
collection Online Access
description Burst generation via a complex bifurcation scenario is discussed using a two compartments model of an enzyme system with substrate inhibition kinetics affected by the production of hydrogen ions accompanying the reaction (e.g. acetylcholinesterase enzyme system). Evidences are given to support the existence of homoclinicity associated with this complex dynamics, including the generalised criterion developed by Rossler et al. [1] for the application of Sil'nikov's theorem in the case of four-dimensional systems. Complex bi-stabilities are observed in certain regions, and the structure of some attracting sets occurring near homoclinic orbits are discussed. The results support the use of such fundamental models for different dynamical modes generation and analysis. The results relate to the transition of small and large frequency oscillations to periodic bursting and vice versa in excitable cells and many biophysical systems.
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spelling upm-510252024-08-07T00:16:32Z http://psasir.upm.edu.my/id/eprint/51025/ Hyperchaos in acetylcholinesterase enzyme systems Ibrahim, Gamal Elnashaie, Said Salah Eldin Hamed Burst generation via a complex bifurcation scenario is discussed using a two compartments model of an enzyme system with substrate inhibition kinetics affected by the production of hydrogen ions accompanying the reaction (e.g. acetylcholinesterase enzyme system). Evidences are given to support the existence of homoclinicity associated with this complex dynamics, including the generalised criterion developed by Rossler et al. [1] for the application of Sil'nikov's theorem in the case of four-dimensional systems. Complex bi-stabilities are observed in certain regions, and the structure of some attracting sets occurring near homoclinic orbits are discussed. The results support the use of such fundamental models for different dynamical modes generation and analysis. The results relate to the transition of small and large frequency oscillations to periodic bursting and vice versa in excitable cells and many biophysical systems. Elsevier Science 1997 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/51025/1/51025.pdf text en http://psasir.upm.edu.my/id/eprint/51025/7/1-s2.0-S0960077996001415-main.pdf Ibrahim, Gamal and Elnashaie, Said Salah Eldin Hamed (1997) Hyperchaos in acetylcholinesterase enzyme systems. Chaos, Solitons & Fractals, 8 (12). pp. 1977-2007. ISSN 0960-0779; ESSN: 1873-2887 http://www.sciencedirect.com/science/article/pii/S0960077996001415 10.1016/S0960-0779(96)00141-5
spellingShingle Ibrahim, Gamal
Elnashaie, Said Salah Eldin Hamed
Hyperchaos in acetylcholinesterase enzyme systems
title Hyperchaos in acetylcholinesterase enzyme systems
title_full Hyperchaos in acetylcholinesterase enzyme systems
title_fullStr Hyperchaos in acetylcholinesterase enzyme systems
title_full_unstemmed Hyperchaos in acetylcholinesterase enzyme systems
title_short Hyperchaos in acetylcholinesterase enzyme systems
title_sort hyperchaos in acetylcholinesterase enzyme systems
url http://psasir.upm.edu.my/id/eprint/51025/
http://psasir.upm.edu.my/id/eprint/51025/
http://psasir.upm.edu.my/id/eprint/51025/
http://psasir.upm.edu.my/id/eprint/51025/1/51025.pdf
http://psasir.upm.edu.my/id/eprint/51025/7/1-s2.0-S0960077996001415-main.pdf