Solitary fibrous tumour of the submandibular region: a rare entity
Solitary fibrous tumours of the head and neck region are extremely rare. The clinical diagnosis is often difficult to establish, and this lesion may be indistinguishable from other soft tissue neoplasms. An 18-year old Chinese gentleman presented with a painless right submandibular swelling which wa...
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/50427/ http://psasir.upm.edu.my/id/eprint/50427/1/FKUSK1_MJMHS_V2_NO2_11.pdf |
| _version_ | 1848851552758923264 |
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| author | Ishak, Noor Liza Sabir Husin Athar, Primuharsa Putra Md Pauzi, Suria Hayati Mohamed Rose, Isa Mohamad Yunus, Mohd Razif |
| author_facet | Ishak, Noor Liza Sabir Husin Athar, Primuharsa Putra Md Pauzi, Suria Hayati Mohamed Rose, Isa Mohamad Yunus, Mohd Razif |
| author_sort | Ishak, Noor Liza |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Solitary fibrous tumours of the head and neck region are extremely rare. The clinical diagnosis is often difficult to establish, and this lesion may be indistinguishable from other soft tissue neoplasms. An 18-year old Chinese gentleman presented with a painless right submandibular swelling which was increasing in size for eight months. A computed tomography scan showed a well-defined solid mass measuring about 2.0 x 2.96 cm in the submandibular region. The tumour was resected and was confined within its capsule.
Immunohistochemical staining was strongly positive for CD34, CD 99, and vimentin and negative for desmin, smooth muscle actin (SMA), cytokeratin, S100 and CD68. The microscopic and immunohistochemical profile were compatible with solitary fibrous tumour. Distinguishing solitary fibrous tumours from various spindle neoplasms can be difficult. In view of the resemblance, immunohistochemical staining can help differentiate solitary fibrous tumour from spindle neoplasm. |
| first_indexed | 2025-11-15T10:24:00Z |
| format | Article |
| id | upm-50427 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:24:00Z |
| publishDate | 2016 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-504272017-02-28T10:30:41Z http://psasir.upm.edu.my/id/eprint/50427/ Solitary fibrous tumour of the submandibular region: a rare entity Ishak, Noor Liza Sabir Husin Athar, Primuharsa Putra Md Pauzi, Suria Hayati Mohamed Rose, Isa Mohamad Yunus, Mohd Razif Solitary fibrous tumours of the head and neck region are extremely rare. The clinical diagnosis is often difficult to establish, and this lesion may be indistinguishable from other soft tissue neoplasms. An 18-year old Chinese gentleman presented with a painless right submandibular swelling which was increasing in size for eight months. A computed tomography scan showed a well-defined solid mass measuring about 2.0 x 2.96 cm in the submandibular region. The tumour was resected and was confined within its capsule. Immunohistochemical staining was strongly positive for CD34, CD 99, and vimentin and negative for desmin, smooth muscle actin (SMA), cytokeratin, S100 and CD68. The microscopic and immunohistochemical profile were compatible with solitary fibrous tumour. Distinguishing solitary fibrous tumours from various spindle neoplasms can be difficult. In view of the resemblance, immunohistochemical staining can help differentiate solitary fibrous tumour from spindle neoplasm. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/50427/1/FKUSK1_MJMHS_V2_NO2_11.pdf Ishak, Noor Liza and Sabir Husin Athar, Primuharsa Putra and Md Pauzi, Suria Hayati and Mohamed Rose, Isa and Mohamad Yunus, Mohd Razif (2016) Solitary fibrous tumour of the submandibular region: a rare entity. Malaysian Journal of Medicine and Health Sciences, 12 (2). pp. 53-55. ISSN 1675-8544 http://www.medic.upm.edu.my/dokumen/FKUSK1_MJMHS_V2_NO2_11.pdf |
| spellingShingle | Ishak, Noor Liza Sabir Husin Athar, Primuharsa Putra Md Pauzi, Suria Hayati Mohamed Rose, Isa Mohamad Yunus, Mohd Razif Solitary fibrous tumour of the submandibular region: a rare entity |
| title | Solitary fibrous tumour of the submandibular region: a rare entity |
| title_full | Solitary fibrous tumour of the submandibular region: a rare entity |
| title_fullStr | Solitary fibrous tumour of the submandibular region: a rare entity |
| title_full_unstemmed | Solitary fibrous tumour of the submandibular region: a rare entity |
| title_short | Solitary fibrous tumour of the submandibular region: a rare entity |
| title_sort | solitary fibrous tumour of the submandibular region: a rare entity |
| url | http://psasir.upm.edu.my/id/eprint/50427/ http://psasir.upm.edu.my/id/eprint/50427/ http://psasir.upm.edu.my/id/eprint/50427/1/FKUSK1_MJMHS_V2_NO2_11.pdf |