Thymoquinone-loaded nanostructured lipid carrier exhibited cytotoxicity towards breast cancer cell lines (MDA-MB-231 and MCF-7) and cervical cancer cell lines (HeLa and SiHa)

QR Code

Thymoquinone-loaded nanostructured lipid carrier exhibited cytotoxicity towards breast cancer cell lines (MDA-MB-231 and MCF-7) and cervical cancer cell lines (HeLa and SiHa)

Thymoquinone (TQ) has been shown to exhibit antitumor properties. Thymoquinone-loaded nanostructured lipid carrier (TQ-NLC) was developed to improve the bioavailability and cytotoxicity of TQ. This study was conducted to determine the cytotoxic effects of TQ-NLC on breast cancer (MDA-MB-231 and MCF-...

Full description

Bibliographic Details
Main Authors:	Wei, Keat Ng, Saiful Yazan, Latifah, Li, Hua Yap, Wan Abd Ghani, Wan Nor Hafiza, Chee, Wun How, Abdullah, Rasedee
Format:	Article
Language:	English
Published:	Hindawi Publishing Corporation 2015
Online Access:	http://psasir.upm.edu.my/id/eprint/46734/ http://psasir.upm.edu.my/id/eprint/46734/1/Thymoquinone-loaded%20nanostructured%20lipid%20carrier%20exhibited%20cytotoxicity%20towards%20breast%20cancer%20cell%20lines%20%28MDA-MB-231%20and%20MCF-7%29%20and%20cervical%20cancer%20cell%20lines%20%28HeLa%20and%20SiHa%29.pdf

Similar Items

Cytotoxicity of thymoquinone and thymoquinone-loaded nanostrustured lipid carrier on cervical cancer cells (SiHa and HeLa)
by: Ng, Wei Keat
Published: (2015)

Design, synthesis and cytotoxic effects of curcuminoids on HeLa, K562, MCF-7 and MDA-MB‑231 cancer cell lines
by: Siti Noor Hajar, Zamrus, et al.
Published: (2018)

Design, synthesis and cytotoxic effects of curcuminoids on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines
by: Zamrus, Siti Noor Hajar, et al.
Published: (2018)

Antioxidant and anti-proliferative activities of Roselle juice on Caov-3, MCF-7, MDA-MB-231 and HeLa cancer cell lines.
by: Md. Akim, Abdah, et al.
Published: (2011)

Effects of Chondroitin Sulfate (CS) on (HeLa) Cervical Cancer and Breast Cancer (MCF-7) cell lines
by: Mazlan, Mazma Syahidatul Ayuni, et al.
Published: (2019)

Antiproliferative Potential of Extracts from Kappaphycus Seaweeds on HeLa Cancer Cell Lines
by: Tiek, Ying Lau, et al.
Published: (2014)

Ampelopsin E reduces the invasiveness of the triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu, et al.
Published: (2019)

Studies of the Anti-Cancer Effects of Flavokawin B Onhuman Breast Cancer Cell Lines, Mcf7 And Mda-Mb-231
by: Sinniah, Ajantha
Published: (2005)

Oncolytic Effect Of Newcastle Disease Virus On The Mcf-7 And Mda-Mb-231 Breast Cancer Cell Lines
by: Meyyappan, Narayani
Published: (2003)

Treatment of MCF-7 and MDA-MB-231 human breast cancer cell lines with erythropoietin, doxorubicin and their combination
by: Radwan, Esam M.
Published: (2015)

Phytochemical screening and anti-cancer effect of Clinacanthus nutans extract towards cervical cancer cell line, HeLa
by: Yee, Lim Wei
Published: (2013)

Thymoquinone, an active ingredient of Black Seed (Nigela saliva) induces distinct apoptotic pathways in C33A and Siha Cervical Cancer Cell Lines)
by: Ichwan, Solachuddin JA, et al.
Published: (2012)

Design, synthesis and cytotoxic effects of curcumin derivatives on K562, MCF-7 and MDA-MB-231 cancer cell lines
by: Akhtar, Muhammad Nadeem, et al.
Published: (2018)

Anticancer Studies Of Ximenia Americana And Catharanthus Roseus In Human Breast Cancer Cell Lines Mcf7 And Mda-Mb-231
by: Eltahir, Nagla Mustafa Eltayeb
Published: (2021)

Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein
by: Ng, Wei Keat, et al.
Published: (2011)

Cytotoxicity of Thymoquinone (TQ) from Nigella sativa towards human cervical carcinoma cells (HeLa).
by: Saiful Yazan, Latifah, et al.
Published: (2009)

Effects of ampelopsin E towards the invasiveness of triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu
Published: (2019)

Establishment of hypoxia-induced invadopodia model and phenotype characterisation of MDA-MB- 231 breast cancer cell line
by: Hamad, Hamad Hamad Ali
Published: (2019)

Effects of co-loaded doxorubicin and thymoquinone calcium carbonate nanoparticles on MDA MB231 breast cancer stem cells
by: Muibat, Ibiyeye Kehinde
Published: (2019)

The detection of DNA damage response in MCF7 and MDA-MB-231 breast cancer cell lines after X-ray exposure
by: Mahmoud, Alkhansa, et al.
Published: (2023)

In vitro treatment of MCF-7 and MDA-MB-231 breast cancer cell lines with doxorubicin and vincristine sulphate calcium carbonate nanoparticles
by: Mengyi, Xue
Published: (2019)

Effect of transforming growth factor-beta1 on oestrogen metabolism in MCF-7 and MDA-MB-231 breast cancer cell lines.
by: Ee, Y.S., et al.
Published: (1999)

Investigation on suitability of pulse duration parameter for HeLa cells line proliferation properties towards anti-cancer application
by: Azizulkarim, Azra Hazwanie, et al.
Published: (2018)

Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
by: Nadiah, Abu, et al.
Published: (2016)

Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases in vitro
by: Abu, Nadiah, et al.
Published: (2016)

Combination effect of tamoxifen and ascorbic acid treatment on breast cancer cells (MCF-7) and cervical cancer cells (HeLa)
by: Hasmah Abdullah,, et al.
Published: (2021)

Cytotoxicity, regulation of apoptotic and anti-apoptotic gene expression by IL-27 in MCF-7 and MDA-MB-231 breast cancer cell lines
by: Yap, Wei Boon, et al.
Published: (2018)

Effects of Gracilaria Changii Extract Onapoptosis snd Gene Expression of Mcf-7and Mda-Mb-23 1 Breast Cancer Cell Lines
by: Abdul Hamid, Nazefah
Published: (2006)

Potential of anti-tumorigenicity and anti-metastasis of annona muricata (soursop leaves) on mcf-7 and mda-mb231 breast cancer cells line
by: Ab Rahman , Husna Shakirah
Published: (2017)

Elucidation Of The Mechanism Involved In The Proliferation And Migration Activity Of Cyperus Esculentus Lativum In Mda-Mb-231 And Mcf7 Breast Cancer Cell Lines
by: Seyram, Elom Achoribo
Published: (2019)

In-vitro evaluation of porcupine bezoar extracts (PBE) as anti-cancer agent on HeLa cell line – A preliminary study
by: Azizulkarim, Azra Hazwanie, et al.
Published: (2018)

Cytotoxicity of Clinacanthus nutans and mechanism of action of its active fraction towards human cervical cancer cell line, HeLA
by: Siti Nur Fatihah Mohd Roslan,, et al.
Published: (2018)

Preliminary screening of anticancer activity using underutilized fruit Baccaurea angulata on breast cancer cell lines (MDA-MB-231)
by: Zulkipli, Aina Farhana, et al.
Published: (2011)

Combination of cisplatin and bromelain exerts synergistic cytotoxic effects against breast cancer cell line MDA-MB-231 in vitro
by: Mat Pauzi, Ahmad Zaim, et al.
Published: (2016)

The role of strobilanthes crispus active fraction (f3) on glucose metabolism of MDA-MB-231 breast cancer cell line
by: Muhammad, Siti Nur Hasyila
Published: (2023)

Anticancer-immune response towards breast cancer cell lines MDA-MB-231 and teratogenic assessment of Pereskia bleo leaves
by: Dalfi, Taif Kareem Khalaf
Published: (2024)

Anti-cancer activities of Thymoquinone, constituents of Nigella sativa against oral cancer cell lines
by: Arief Ichwan, Solachuddin Jauhari, et al.
Published: (2010)

Antiproliferative activity of bruceajavanica fruits extract towards hela cancer cell lines
by: Maslinda, Mansor
Published: (2008)

DNA fragmentation in hela cancer cell lines treated with syzygium polyanthum extracts
by: Abdullah, Mastura
Published: (2008)

Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis
by: Armania, Nurdin, et al.
Published: (2013)