The first Malay database toward the ethnic-specific target molecular variation
BACKGROUND:The Malaysian Node of the Human Variome Project (MyHVP) is one of the eighteen official Human Variome Project (HVP) country-specific nodes. Since its inception in 9(th) October 2010, MyHVP has attracted the significant number of Malaysian clinicians and researchers to participate and cont...
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| Format: | Article |
| Language: | English |
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BioMed Central
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/46597/ http://psasir.upm.edu.my/id/eprint/46597/1/The%20first%20Malay%20database%20toward%20the%20ethnic-specific%20target%20molecular%20variation.pdf |
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| author | Fikri, Hashim Halim Etemad, Ali Abdul Latif, Ahmad Zubaidi Merican, Amir Feisal Baig, Atif Amin Annuar, Azlina Ahmad Ismail, Endom Salahshourifar, Iman Liza Sharmini, Ahmad Tajudin Ramli, Marini Shah, Mohamed Irwan Johan, Muhammad Farid Nik Hassan, Nik Norliza Abdul Aziz, Noraishah Mydin Mohd Noor, Noor Haslina Ab Rajab, Nur Shafawati Hassan, Rosline Bahar, Rosnah Zain, Rosnah Mohamed Yusoff, Shafini Yusoff, Surini Soon, Guan Tan Meow, Keong Thong Wan Isa, Hatin Abdullah, Wan Zaidah Mohamed, Zahurin Abdul Latiff, Zarina Zilfalil, Alwi |
| author_facet | Fikri, Hashim Halim Etemad, Ali Abdul Latif, Ahmad Zubaidi Merican, Amir Feisal Baig, Atif Amin Annuar, Azlina Ahmad Ismail, Endom Salahshourifar, Iman Liza Sharmini, Ahmad Tajudin Ramli, Marini Shah, Mohamed Irwan Johan, Muhammad Farid Nik Hassan, Nik Norliza Abdul Aziz, Noraishah Mydin Mohd Noor, Noor Haslina Ab Rajab, Nur Shafawati Hassan, Rosline Bahar, Rosnah Zain, Rosnah Mohamed Yusoff, Shafini Yusoff, Surini Soon, Guan Tan Meow, Keong Thong Wan Isa, Hatin Abdullah, Wan Zaidah Mohamed, Zahurin Abdul Latiff, Zarina Zilfalil, Alwi |
| author_sort | Fikri, Hashim Halim |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | BACKGROUND:The Malaysian Node of the Human Variome Project (MyHVP) is one of the eighteen official Human Variome Project (HVP) country-specific nodes. Since its inception in 9(th) October 2010, MyHVP has attracted the significant number of Malaysian clinicians and researchers to participate and contribute their data to this project. MyHVP also act as the center of coordination for genotypic and phenotypic variation studies of the Malaysian population. A specialized database was developed to store and manage the data based on genetic variations which also associated with health and disease of Malaysian ethnic groups. This ethnic-specific database is called the Malaysian Node of the Human Variome Project database (MyHVPDb).
FINDINGS:Currently, MyHVPDb provides only information about the genetic variations and mutations found in the Malays. In the near future, it will expand for the other Malaysian ethnics as well. The data sets are specified based on diseases or genetic mutation types which have three main subcategories: Single Nucleotide Polymorphism (SNP), Copy Number Variation (CNV) followed by the mutations which code for the common diseases among Malaysians. MyHVPDb has been open to the local researchers, academicians and students through the registration at the portal of MyHVP ( http://hvpmalaysia.kk.usm.my/mhgvc/index.php?id=register ).
CONCLUSIONS:This database would be useful for clinicians and researchers who are interested in doing a study on genomics population and genetic diseases in order to obtain up-to-date and accurate information regarding the population-specific variations and also useful for those in countries with similar ethnic background. |
| first_indexed | 2025-11-15T10:10:23Z |
| format | Article |
| id | upm-46597 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:10:23Z |
| publishDate | 2015 |
| publisher | BioMed Central |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-465972018-03-20T04:39:20Z http://psasir.upm.edu.my/id/eprint/46597/ The first Malay database toward the ethnic-specific target molecular variation Fikri, Hashim Halim Etemad, Ali Abdul Latif, Ahmad Zubaidi Merican, Amir Feisal Baig, Atif Amin Annuar, Azlina Ahmad Ismail, Endom Salahshourifar, Iman Liza Sharmini, Ahmad Tajudin Ramli, Marini Shah, Mohamed Irwan Johan, Muhammad Farid Nik Hassan, Nik Norliza Abdul Aziz, Noraishah Mydin Mohd Noor, Noor Haslina Ab Rajab, Nur Shafawati Hassan, Rosline Bahar, Rosnah Zain, Rosnah Mohamed Yusoff, Shafini Yusoff, Surini Soon, Guan Tan Meow, Keong Thong Wan Isa, Hatin Abdullah, Wan Zaidah Mohamed, Zahurin Abdul Latiff, Zarina Zilfalil, Alwi BACKGROUND:The Malaysian Node of the Human Variome Project (MyHVP) is one of the eighteen official Human Variome Project (HVP) country-specific nodes. Since its inception in 9(th) October 2010, MyHVP has attracted the significant number of Malaysian clinicians and researchers to participate and contribute their data to this project. MyHVP also act as the center of coordination for genotypic and phenotypic variation studies of the Malaysian population. A specialized database was developed to store and manage the data based on genetic variations which also associated with health and disease of Malaysian ethnic groups. This ethnic-specific database is called the Malaysian Node of the Human Variome Project database (MyHVPDb). FINDINGS:Currently, MyHVPDb provides only information about the genetic variations and mutations found in the Malays. In the near future, it will expand for the other Malaysian ethnics as well. The data sets are specified based on diseases or genetic mutation types which have three main subcategories: Single Nucleotide Polymorphism (SNP), Copy Number Variation (CNV) followed by the mutations which code for the common diseases among Malaysians. MyHVPDb has been open to the local researchers, academicians and students through the registration at the portal of MyHVP ( http://hvpmalaysia.kk.usm.my/mhgvc/index.php?id=register ). CONCLUSIONS:This database would be useful for clinicians and researchers who are interested in doing a study on genomics population and genetic diseases in order to obtain up-to-date and accurate information regarding the population-specific variations and also useful for those in countries with similar ethnic background. BioMed Central 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/46597/1/The%20first%20Malay%20database%20toward%20the%20ethnic-specific%20target%20molecular%20variation.pdf Fikri, Hashim Halim and Etemad, Ali and Abdul Latif, Ahmad Zubaidi and Merican, Amir Feisal and Baig, Atif Amin and Annuar, Azlina Ahmad and Ismail, Endom and Salahshourifar, Iman and Liza Sharmini, Ahmad Tajudin and Ramli, Marini and Shah, Mohamed Irwan and Johan, Muhammad Farid and Nik Hassan, Nik Norliza and Abdul Aziz, Noraishah Mydin and Mohd Noor, Noor Haslina and Ab Rajab, Nur Shafawati and Hassan, Rosline and Bahar, Rosnah and Zain, Rosnah and Mohamed Yusoff, Shafini and Yusoff, Surini and Soon, Guan Tan and Meow, Keong Thong and Wan Isa, Hatin and Abdullah, Wan Zaidah and Mohamed, Zahurin and Abdul Latiff, Zarina and Zilfalil, Alwi (2015) The first Malay database toward the ethnic-specific target molecular variation. BMC Research Notes, 8 (176). pp. 1-6. ISSN 1756-0500 10.1186/s13104-015-1123-y |
| spellingShingle | Fikri, Hashim Halim Etemad, Ali Abdul Latif, Ahmad Zubaidi Merican, Amir Feisal Baig, Atif Amin Annuar, Azlina Ahmad Ismail, Endom Salahshourifar, Iman Liza Sharmini, Ahmad Tajudin Ramli, Marini Shah, Mohamed Irwan Johan, Muhammad Farid Nik Hassan, Nik Norliza Abdul Aziz, Noraishah Mydin Mohd Noor, Noor Haslina Ab Rajab, Nur Shafawati Hassan, Rosline Bahar, Rosnah Zain, Rosnah Mohamed Yusoff, Shafini Yusoff, Surini Soon, Guan Tan Meow, Keong Thong Wan Isa, Hatin Abdullah, Wan Zaidah Mohamed, Zahurin Abdul Latiff, Zarina Zilfalil, Alwi The first Malay database toward the ethnic-specific target molecular variation |
| title | The first Malay database toward the ethnic-specific target molecular variation |
| title_full | The first Malay database toward the ethnic-specific target molecular variation |
| title_fullStr | The first Malay database toward the ethnic-specific target molecular variation |
| title_full_unstemmed | The first Malay database toward the ethnic-specific target molecular variation |
| title_short | The first Malay database toward the ethnic-specific target molecular variation |
| title_sort | first malay database toward the ethnic-specific target molecular variation |
| url | http://psasir.upm.edu.my/id/eprint/46597/ http://psasir.upm.edu.my/id/eprint/46597/ http://psasir.upm.edu.my/id/eprint/46597/1/The%20first%20Malay%20database%20toward%20the%20ethnic-specific%20target%20molecular%20variation.pdf |