Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines
Three novel ruthenium(II) complexes of the general formula [Ru(II)(bpy)2L]2+ were synthesized, where L = 1,10-phenanthroline derivatives of position 2 imidazole having 3,4-didecyloxy-phenyl (ddip), 3,4-ditetradecyloxy-phenyl (dtip) and 3,4-dihexadecyloxy-phenyl (dhip). All complexes were characteriz...
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| Format: | Article |
| Language: | English |
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Universiti Kebangsaan Malaysia
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/46480/ http://psasir.upm.edu.my/id/eprint/46480/1/Synthesis%2C%20characterization%20and%20DNA%20binding%20studies%20of%20%5BRuthenium%28II%29%28bpy%292L%5D2%2B%20where%20L%20are%20derivatives%20of%20imidazo%5B4%2C5-f%5D-1%2C10-phenanthrolines.pdf |
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| author | Ting, T. T. C. Crouse, K. A. Ahmad, H. |
| author_facet | Ting, T. T. C. Crouse, K. A. Ahmad, H. |
| author_sort | Ting, T. T. C. |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Three novel ruthenium(II) complexes of the general formula [Ru(II)(bpy)2L]2+ were synthesized, where L = 1,10-phenanthroline derivatives of position 2 imidazole having 3,4-didecyloxy-phenyl (ddip), 3,4-ditetradecyloxy-phenyl (dtip) and 3,4-dihexadecyloxy-phenyl (dhip). All complexes were characterized by elemental analysis, 1H-NMR and ESI-MS. Their photophysical properties have also been studied by UV-visible spectroscopy and fluorescence spectroscopy. The complexes exhibit Ru(II) metal centered emission at approximately 610 nm in acetonitrile solution at room temperature. DNA binding studies were carried out by UV-visible titration, luminescence titration and viscosity studies. The results indicated that [Ru(bpy)2(ddip)]2+ binds to CT-DNA by partial intercalation mode, while [Ru(bpy)2(dtip)]2+ and [Ru(bpy)2(dhip)]2+ bind intercalatively via extended ligands. |
| first_indexed | 2025-11-15T10:09:58Z |
| format | Article |
| id | upm-46480 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:09:58Z |
| publishDate | 2015 |
| publisher | Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-464802018-02-27T03:34:51Z http://psasir.upm.edu.my/id/eprint/46480/ Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines Ting, T. T. C. Crouse, K. A. Ahmad, H. Three novel ruthenium(II) complexes of the general formula [Ru(II)(bpy)2L]2+ were synthesized, where L = 1,10-phenanthroline derivatives of position 2 imidazole having 3,4-didecyloxy-phenyl (ddip), 3,4-ditetradecyloxy-phenyl (dtip) and 3,4-dihexadecyloxy-phenyl (dhip). All complexes were characterized by elemental analysis, 1H-NMR and ESI-MS. Their photophysical properties have also been studied by UV-visible spectroscopy and fluorescence spectroscopy. The complexes exhibit Ru(II) metal centered emission at approximately 610 nm in acetonitrile solution at room temperature. DNA binding studies were carried out by UV-visible titration, luminescence titration and viscosity studies. The results indicated that [Ru(bpy)2(ddip)]2+ binds to CT-DNA by partial intercalation mode, while [Ru(bpy)2(dtip)]2+ and [Ru(bpy)2(dhip)]2+ bind intercalatively via extended ligands. Universiti Kebangsaan Malaysia 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/46480/1/Synthesis%2C%20characterization%20and%20DNA%20binding%20studies%20of%20%5BRuthenium%28II%29%28bpy%292L%5D2%2B%20where%20L%20are%20derivatives%20of%20imidazo%5B4%2C5-f%5D-1%2C10-phenanthrolines.pdf Ting, T. T. C. and Crouse, K. A. and Ahmad, H. (2015) Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines. Sains Malaysiana, 44 (4). pp. 619-628. ISSN 0026-6039 10.17576/jsm-2015-4404-18 |
| spellingShingle | Ting, T. T. C. Crouse, K. A. Ahmad, H. Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title | Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_full | Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_fullStr | Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_full_unstemmed | Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_short | Synthesis, characterization and DNA binding studies of [Ruthenium(II)(bpy)2L]2+ where L are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| title_sort | synthesis, characterization and dna binding studies of [ruthenium(ii)(bpy)2l]2+ where l are derivatives of imidazo[4,5-f]-1,10-phenanthrolines |
| url | http://psasir.upm.edu.my/id/eprint/46480/ http://psasir.upm.edu.my/id/eprint/46480/ http://psasir.upm.edu.my/id/eprint/46480/1/Synthesis%2C%20characterization%20and%20DNA%20binding%20studies%20of%20%5BRuthenium%28II%29%28bpy%292L%5D2%2B%20where%20L%20are%20derivatives%20of%20imidazo%5B4%2C5-f%5D-1%2C10-phenanthrolines.pdf |