Probiotic or antibiotic: future challenges in medicine
Genetic and environmental factors can affect the intestinal microbiome and microbial metabolome. Among these environmental factors, the consumption of antibiotics can significantly change the intestinal microbiome of individuals and consequently affect the corresponding metagenome. The term 'pr...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Society for General Microbiology
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/46008/ http://psasir.upm.edu.my/id/eprint/46008/1/Probiotic%20or%20antibiotic%20future%20challenges%20in%20medicine.pdf |
| _version_ | 1848850577032740864 |
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| author | Nami, Yousef Haghshenas, Babak Abdullah, Norhafizah Barzegari, Abolfazl Awang Biak, Dayang Radiah Rosli, Rozita Khosroushahi, Ahmad Yari |
| author_facet | Nami, Yousef Haghshenas, Babak Abdullah, Norhafizah Barzegari, Abolfazl Awang Biak, Dayang Radiah Rosli, Rozita Khosroushahi, Ahmad Yari |
| author_sort | Nami, Yousef |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Genetic and environmental factors can affect the intestinal microbiome and microbial metabolome. Among these environmental factors, the consumption of antibiotics can significantly change the intestinal microbiome of individuals and consequently affect the corresponding metagenome. The term 'probiotics' is related to preventive medicine rather than therapeutic procedures and is, thus, considered the opposite of antibiotics. This review discusses the challenges between these opposing treatments in terms of the following points: (i) antibiotic resistance, the relationship between antibiotic consumption and microbiome diversity reduction, antibiotic effect on the metagenome, and disease associated with antibiotics; and (ii) probiotics as living drugs, probiotic effect on epigenetic alterations, and gut microbiome relevance to hygiene indulgence. The intestinal microbiome is more specific for individuals and may be affected by environmental alterations and the occurrence of diseases. |
| first_indexed | 2025-11-15T10:08:30Z |
| format | Article |
| id | upm-46008 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:08:30Z |
| publishDate | 2015 |
| publisher | Society for General Microbiology |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-460082018-05-14T08:46:50Z http://psasir.upm.edu.my/id/eprint/46008/ Probiotic or antibiotic: future challenges in medicine Nami, Yousef Haghshenas, Babak Abdullah, Norhafizah Barzegari, Abolfazl Awang Biak, Dayang Radiah Rosli, Rozita Khosroushahi, Ahmad Yari Genetic and environmental factors can affect the intestinal microbiome and microbial metabolome. Among these environmental factors, the consumption of antibiotics can significantly change the intestinal microbiome of individuals and consequently affect the corresponding metagenome. The term 'probiotics' is related to preventive medicine rather than therapeutic procedures and is, thus, considered the opposite of antibiotics. This review discusses the challenges between these opposing treatments in terms of the following points: (i) antibiotic resistance, the relationship between antibiotic consumption and microbiome diversity reduction, antibiotic effect on the metagenome, and disease associated with antibiotics; and (ii) probiotics as living drugs, probiotic effect on epigenetic alterations, and gut microbiome relevance to hygiene indulgence. The intestinal microbiome is more specific for individuals and may be affected by environmental alterations and the occurrence of diseases. Society for General Microbiology 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/46008/1/Probiotic%20or%20antibiotic%20future%20challenges%20in%20medicine.pdf Nami, Yousef and Haghshenas, Babak and Abdullah, Norhafizah and Barzegari, Abolfazl and Awang Biak, Dayang Radiah and Rosli, Rozita and Khosroushahi, Ahmad Yari (2015) Probiotic or antibiotic: future challenges in medicine. Journal of Medical Microbiology, 64 (2). pp. 137-146. ISSN 0022-2615; ESSN: 1473-5644 10.1099/jmm.0.078923-0 |
| spellingShingle | Nami, Yousef Haghshenas, Babak Abdullah, Norhafizah Barzegari, Abolfazl Awang Biak, Dayang Radiah Rosli, Rozita Khosroushahi, Ahmad Yari Probiotic or antibiotic: future challenges in medicine |
| title | Probiotic or antibiotic: future challenges in medicine |
| title_full | Probiotic or antibiotic: future challenges in medicine |
| title_fullStr | Probiotic or antibiotic: future challenges in medicine |
| title_full_unstemmed | Probiotic or antibiotic: future challenges in medicine |
| title_short | Probiotic or antibiotic: future challenges in medicine |
| title_sort | probiotic or antibiotic: future challenges in medicine |
| url | http://psasir.upm.edu.my/id/eprint/46008/ http://psasir.upm.edu.my/id/eprint/46008/ http://psasir.upm.edu.my/id/eprint/46008/1/Probiotic%20or%20antibiotic%20future%20challenges%20in%20medicine.pdf |