Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus
Introduction:We assessed the predictors of poor glycaemic control among older patients with type 2 diabetes mellitus (T2DM) in Malaysia. Methods:This cross-sectional study used the data of 21,336 patients aged ≥ 60 years with T2DM from the Adult Diabetes Control and Management Registry 2008-2009....
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Singapore Medical Association
2015
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/45941/ http://psasir.upm.edu.my/id/eprint/45941/1/Predictors%20of%20poor%20glycaemic%20control%20in%20older%20patients%20with%20type%202%20diabetes%20mellitus.pdf |
| _version_ | 1848850564919590912 |
|---|---|
| author | Shariff Ghazali, Sazlina Ismail, Mastura Cheong, Ai Theng Bujang, Mohamad Adam Haniff, Jamaiyah Lee, Ping Yein Syed Abdul Rahman, Syed Alwi Chew, Boon How |
| author_facet | Shariff Ghazali, Sazlina Ismail, Mastura Cheong, Ai Theng Bujang, Mohamad Adam Haniff, Jamaiyah Lee, Ping Yein Syed Abdul Rahman, Syed Alwi Chew, Boon How |
| author_sort | Shariff Ghazali, Sazlina |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Introduction:We assessed the predictors of poor glycaemic control among older patients with type 2 diabetes mellitus (T2DM) in Malaysia.
Methods:This cross-sectional study used the data of 21,336 patients aged ≥ 60 years with T2DM from the Adult Diabetes Control and Management Registry 2008-2009.
Results:Predictors of poor glycaemic control were: age groups 60-69 years (odds ratio [OR] 1.96, 95% confidence interval [CI] 1.66-2.33) and 70-79 years (OR 1.43, 95% CI 1.20-1.71); Malay (OR 1.53, 95% CI 1.41-1.66) and Indian (OR 1.32, 95% CI 1.19-1.46) ethnicities; T2DM durations of 5-10 years (OR 1.46, 95% CI 1.35-1.58) and > 10 years (OR 1.75, 95% CI 1.59-1.91); the use of oral antidiabetic agents only (OR 5.86, 95% CI 3.32-10.34), insulin only (OR 17.93, 95% CI 9.91-32.43), and oral antidiabetic agents and insulin (OR 29.42, 95% CI 16.47-52.53); and elevated blood pressure (OR 1.10, 95% CI 1.01-1.20), low-density lipoprotein cholesterol (OR 1.48, 95% CI 1.38-1.59) and triglycerides (OR 1.61, 95% CI 1.51-1.73). Hypertension (OR 0.71, 95% CI 0.64-0.80), hypertension and dyslipidaemia (OR 0.68, 95% CI 0.61-0.75), pre-obesity (OR 0.89, 95% CI 0.82-0.98) and obesity (OR 0.76, 95% CI 0.70-0.84) were less likely to be associated with poor glycaemic control.
Conclusion:Young-old and middle-old age groups (i.e. < 80 years), Malay and Indian ethnicities, longer T2DM duration, the use of pharmacological agents, and elevated blood pressure and lipid levels were associated with poor glycaemic control. The presence of comorbidities, pre-obesity and obesity were less likely to be associated with poor glycaemic control. |
| first_indexed | 2025-11-15T10:08:18Z |
| format | Article |
| id | upm-45941 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:08:18Z |
| publishDate | 2015 |
| publisher | Singapore Medical Association |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-459412019-11-25T08:26:16Z http://psasir.upm.edu.my/id/eprint/45941/ Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus Shariff Ghazali, Sazlina Ismail, Mastura Cheong, Ai Theng Bujang, Mohamad Adam Haniff, Jamaiyah Lee, Ping Yein Syed Abdul Rahman, Syed Alwi Chew, Boon How Introduction:We assessed the predictors of poor glycaemic control among older patients with type 2 diabetes mellitus (T2DM) in Malaysia. Methods:This cross-sectional study used the data of 21,336 patients aged ≥ 60 years with T2DM from the Adult Diabetes Control and Management Registry 2008-2009. Results:Predictors of poor glycaemic control were: age groups 60-69 years (odds ratio [OR] 1.96, 95% confidence interval [CI] 1.66-2.33) and 70-79 years (OR 1.43, 95% CI 1.20-1.71); Malay (OR 1.53, 95% CI 1.41-1.66) and Indian (OR 1.32, 95% CI 1.19-1.46) ethnicities; T2DM durations of 5-10 years (OR 1.46, 95% CI 1.35-1.58) and > 10 years (OR 1.75, 95% CI 1.59-1.91); the use of oral antidiabetic agents only (OR 5.86, 95% CI 3.32-10.34), insulin only (OR 17.93, 95% CI 9.91-32.43), and oral antidiabetic agents and insulin (OR 29.42, 95% CI 16.47-52.53); and elevated blood pressure (OR 1.10, 95% CI 1.01-1.20), low-density lipoprotein cholesterol (OR 1.48, 95% CI 1.38-1.59) and triglycerides (OR 1.61, 95% CI 1.51-1.73). Hypertension (OR 0.71, 95% CI 0.64-0.80), hypertension and dyslipidaemia (OR 0.68, 95% CI 0.61-0.75), pre-obesity (OR 0.89, 95% CI 0.82-0.98) and obesity (OR 0.76, 95% CI 0.70-0.84) were less likely to be associated with poor glycaemic control. Conclusion:Young-old and middle-old age groups (i.e. < 80 years), Malay and Indian ethnicities, longer T2DM duration, the use of pharmacological agents, and elevated blood pressure and lipid levels were associated with poor glycaemic control. The presence of comorbidities, pre-obesity and obesity were less likely to be associated with poor glycaemic control. Singapore Medical Association 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/45941/1/Predictors%20of%20poor%20glycaemic%20control%20in%20older%20patients%20with%20type%202%20diabetes%20mellitus.pdf Shariff Ghazali, Sazlina and Ismail, Mastura and Cheong, Ai Theng and Bujang, Mohamad Adam and Haniff, Jamaiyah and Lee, Ping Yein and Syed Abdul Rahman, Syed Alwi and Chew, Boon How (2015) Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus. Singapore Medical Journal, 56 (5). pp. 284-290. ISSN 0037-5675 http://www.smj.org.sg/article/predictors-poor-glycaemic-control-older-patients-type-2-diabetes-mellitus 10.11622/smedj.2015055 |
| spellingShingle | Shariff Ghazali, Sazlina Ismail, Mastura Cheong, Ai Theng Bujang, Mohamad Adam Haniff, Jamaiyah Lee, Ping Yein Syed Abdul Rahman, Syed Alwi Chew, Boon How Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus |
| title | Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus |
| title_full | Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus |
| title_fullStr | Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus |
| title_full_unstemmed | Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus |
| title_short | Predictors of poor glycaemic control in older patients with type 2 diabetes mellitus |
| title_sort | predictors of poor glycaemic control in older patients with type 2 diabetes mellitus |
| url | http://psasir.upm.edu.my/id/eprint/45941/ http://psasir.upm.edu.my/id/eprint/45941/ http://psasir.upm.edu.my/id/eprint/45941/ http://psasir.upm.edu.my/id/eprint/45941/1/Predictors%20of%20poor%20glycaemic%20control%20in%20older%20patients%20with%20type%202%20diabetes%20mellitus.pdf |