Nanoemulsion-based parenteral drug delivery system of carbamazepine: preparation, characterization, stability evaluation and blood-brain pharmacokinetics
Carbamzepine (CBZ) was encapsulated in a parenteral oil-in-water nanoemulsion, in an attempt to improve its bioavailability. The particle size, polydispersity index and zeta potential were measured using dynamic light scattering. Other parameters such as pH, osmolality, viscosity, drug loading effic...
| Main Authors: | Tan, Sim Ling, Stanslas, Johnson, Basri, Mahiran, Abedi Karjiban, Roghayeh, Kirby, Brian P., Sani, Dahiru, Basri, Hamidon |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bentham Science Publishers
2015
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/45574/ http://psasir.upm.edu.my/id/eprint/45574/1/Nanoemulsion-based%20parenteral%20drug%20delivery%20system%20.pdf |
Similar Items
Ultrasonic emulsification of parenteral valproic acid-loaded nanoemulsion with response surface methodology and evaluation of its stability
by: Tan, Suk Fei, et al.
Published: (2016)
by: Tan, Suk Fei, et al.
Published: (2016)
Development of parenteral nanoemulsion systems loaded with carbamazepine for efficient blood-brain barrier crossing in epilepsy treatment
by: Tan, Sim Ling
Published: (2016)
by: Tan, Sim Ling
Published: (2016)
Computational simulation of palm kernel oil-based esters nano-emulsions aggregation as a potential parenteral drug delivery system
by: Faujan, Nur Hana, et al.
Published: (2019)
by: Faujan, Nur Hana, et al.
Published: (2019)
Development of nanoemulsion for efficient brain parental delivery of cefuroxime: designs,characterizations,and pharmacokinetics
by: Harun, Siti Norhawani, et al.
Published: (2018)
by: Harun, Siti Norhawani, et al.
Published: (2018)
Predicting the optimum compositions of a parenteral nanoemulsion system loaded with azithromycin antibiotic utilizing the artificial neural network model
by: S. Daood, Ghaidaa, et al.
Published: (2015)
by: S. Daood, Ghaidaa, et al.
Published: (2015)
Characterisation, in-vitro and in-vivo evaluation of valproic acid-loaded nanoemulsion for improved brain bioavailability
by: Tan, Suk Fei, et al.
Published: (2017)
by: Tan, Suk Fei, et al.
Published: (2017)
Physicochemical characterization and thermodynamic studies of nanoemulsion-based transdermal delivery system for fullerene
by: Cheng, Loong Ngan, et al.
Published: (2014)
by: Cheng, Loong Ngan, et al.
Published: (2014)
Improvement of physicochemical properties of nanocolloidal carrier loaded with low water solubility drug for parenteral cancer treatment by response surface methodology
by: Salim, Norazlinaliza, et al.
Published: (2019)
by: Salim, Norazlinaliza, et al.
Published: (2019)
The palm kernel oil ester nanoemulsion system using pluronic F-127 as a polymeric surfactant via a high energy emulsification method
by: Zahari, Noor Izah, et al.
Published: (2014)
by: Zahari, Noor Izah, et al.
Published: (2014)
Comparison of process parameter optimization using different designs in nanoemulsion - based formulation for transdermal delivery of fullerene
by: Cheng, Loong Ngan, et al.
Published: (2014)
by: Cheng, Loong Ngan, et al.
Published: (2014)
Skin intervention of fullerene-integrated nanoemulsion in structural and collagen regeneration against skin aging
by: Cheng, Loong Ngan, et al.
Published: (2015)
by: Cheng, Loong Ngan, et al.
Published: (2015)
Parenteral formulation of nanoemulsion loaded with chloramphenicol for meningitis treatment
by: Musa, Siti Hajar
Published: (2014)
by: Musa, Siti Hajar
Published: (2014)
Formulation optimization of palm kernel oil esters nanoemulsion-loaded with chloramphenicol suitable for meningitis treatment
by: Musa, Siti Hajar, et al.
Published: (2013)
by: Musa, Siti Hajar, et al.
Published: (2013)
Prediction of optimum compositions of parenteral nanoemulsion system loaded with low solubility drug for treatment of schizophrenia by artificial neural network
by: Samiun, Wan Sarah, et al.
Published: (2016)
by: Samiun, Wan Sarah, et al.
Published: (2016)
Design and development of a nanoemulsion system containing copper peptide by D-optimal mixture design and evaluation of its physicochemical properties
by: Samson, Shazwani, et al.
Published: (2016)
by: Samson, Shazwani, et al.
Published: (2016)
An artificial neural network based analysis of factors controlling particle size in a virgin coconut oil-based nanoemulsion system containing copper peptide
by: Samson, Shazwani, et al.
Published: (2016)
by: Samson, Shazwani, et al.
Published: (2016)
Formulation development and optimization of palm kernel oil esters-based nanoemulsions containing sodium diclofenac
by: Rezaee, Malahat, et al.
Published: (2014)
by: Rezaee, Malahat, et al.
Published: (2014)
The effect of temperature and pressure on the self-assembly of dipalmitoylphosphatidylcholine using coarse-grained molecular dynamics
by: Shaari, Nurul Syahidah, et al.
Published: (2014)
by: Shaari, Nurul Syahidah, et al.
Published: (2014)
Nanoemulsion as a topical delivery system of antipsoriatic drugs
by: Salim, Norazlinaliza, et al.
Published: (2016)
by: Salim, Norazlinaliza, et al.
Published: (2016)
In Vitro blood-brain barrier models for neuroinfectious diseases: a narrative review
by: Badawi, Ahmad Hussein, et al.
Published: (2024)
by: Badawi, Ahmad Hussein, et al.
Published: (2024)
Formation of stable palm kernel oil esters nanoemulsion system containing hydrocortisone
by: Da Costa, Stephanie, et al.
Published: (2014)
by: Da Costa, Stephanie, et al.
Published: (2014)
In vitro evaluation of the inhalable quercetin loaded nanoemulsion for pulmonary delivery
by: Arbain, Noor Hafizah, et al.
Published: (2018)
by: Arbain, Noor Hafizah, et al.
Published: (2018)
Development and characterization of parenteral nano-delivery system loaded with azithromycin
by: Daood, Ghaidaa S
Published: (2016)
by: Daood, Ghaidaa S
Published: (2016)
Molecular Dynamics of Thermoalkalophilic Lipases Unfolding At High Temperatures
by: Karjiban, Roghayeh Abedi
Published: (2008)
by: Karjiban, Roghayeh Abedi
Published: (2008)
Stability of positively charged nanoemulsion formulation containing steroidal drug for effective transdermal application
by: Da Costa, Stephanie, et al.
Published: (2014)
by: Da Costa, Stephanie, et al.
Published: (2014)
Nose to brain delivery of selegiline loaded PLGA/lipid nanoparticles : Synthesis, characterisation and brain pharmacokinetics evaluation
by: Raman, Subashini, et al.
Published: (2022)
by: Raman, Subashini, et al.
Published: (2022)
Optimization of quercetin loaded palm oil ester based nanoemulsion formulation for pulmonary delivery
by: Arbain, Noor Hafizah, et al.
Published: (2018)
by: Arbain, Noor Hafizah, et al.
Published: (2018)
A coarse-grained molecular dynamics study of DLPC, DMPC, DPPC, and DSPC mixtures in aqueous solution
by: Karjiban, Roghayeh Abedi, et al.
Published: (2013)
by: Karjiban, Roghayeh Abedi, et al.
Published: (2013)
Andrographolide downregulates pro-inflammatory cytokines and free radical productions to prevent dopaminergic neuro-degeneration induced by lipopolysaccharide
by: Sani, Dahiru, et al.
Published: (2014)
by: Sani, Dahiru, et al.
Published: (2014)
Transformation of carbamazepine dihydrate to anhydrous carbamazepine
by: Noraini, Ghazali
Published: (2015)
by: Noraini, Ghazali
Published: (2015)
Molecular dynamics of thermoenzymes at high temperature and pressure: a review
by: Karjiban, Roghayeh Abedi, et al.
Published: (2014)
by: Karjiban, Roghayeh Abedi, et al.
Published: (2014)
Structural properties of nonionic Tween80 micelle in water
elucidated by molecular dynamics simulation.
by: Karjiban, Roghayeh Abedi, et al.
Published: (2012)
by: Karjiban, Roghayeh Abedi, et al.
Published: (2012)
Molecular dynamics simulation of palmitate ester self-assembly with diclofenac
by: Karjiban, Roghayeh Abedi, et al.
Published: (2012)
by: Karjiban, Roghayeh Abedi, et al.
Published: (2012)
Targeted drug delivery to the brain via intranasal nanoemulsion: available proof of concept and existing challenges
by: Chatterjee, Bappaditya, et al.
Published: (2019)
by: Chatterjee, Bappaditya, et al.
Published: (2019)
Pharmacokinetic and pharmacodynamic features of nanoemulsion following oral, intravenous, topical and nasal route
by: Chowdhury, Hira, et al.
Published: (2017)
by: Chowdhury, Hira, et al.
Published: (2017)
Compatibility of pentoxifylline and parenteral medications
by: Campbell, A.L., et al.
Published: (2020)
by: Campbell, A.L., et al.
Published: (2020)
Monte Carlo simulation of mixed nonionic Brij surfactants in water
by: Yahya, Ruzanna, et al.
Published: (2014)
by: Yahya, Ruzanna, et al.
Published: (2014)
Phase behavior, formation and characterization of palm-based esters nanoemulsion formulation containing ibuprofen.
by: Salim, Norazlinaliza, et al.
Published: (2011)
by: Salim, Norazlinaliza, et al.
Published: (2011)
Formulation of a nanoemulsion for topical delivery of raloxifene
by: Hasan Ali, Ebrahim Mohammed, et al.
Published: (2017)
by: Hasan Ali, Ebrahim Mohammed, et al.
Published: (2017)
Fabrication of nanoemulsion loaded with cefuroxime for efficient translocation across the blood brain barrier
by: Harun, Siti Norhawani
Published: (2018)
by: Harun, Siti Norhawani
Published: (2018)
Similar Items
-
Ultrasonic emulsification of parenteral valproic acid-loaded nanoemulsion with response surface methodology and evaluation of its stability
by: Tan, Suk Fei, et al.
Published: (2016) -
Development of parenteral nanoemulsion systems loaded with carbamazepine for efficient blood-brain barrier crossing in epilepsy treatment
by: Tan, Sim Ling
Published: (2016) -
Computational simulation of palm kernel oil-based esters nano-emulsions aggregation as a potential parenteral drug delivery system
by: Faujan, Nur Hana, et al.
Published: (2019) -
Development of nanoemulsion for efficient brain parental delivery of cefuroxime: designs,characterizations,and pharmacokinetics
by: Harun, Siti Norhawani, et al.
Published: (2018) -
Predicting the optimum compositions of a parenteral nanoemulsion system loaded with azithromycin antibiotic utilizing the artificial neural network model
by: S. Daood, Ghaidaa, et al.
Published: (2015)