In vivo antitumor and antimetastatic effects of flavokawain B in 4T1 breast cancer cell-challenged mice

QR Code

In vivo antitumor and antimetastatic effects of flavokawain B in 4T1 breast cancer cell-challenged mice

Flavokawain B (FKB) is a naturally occurring chalcone that can be isolated through the root extracts of the kava-kava plant (Piper methysticum). It can also be synthesized chemically to increase the yield. This compound is a promising candidate as a biological agent, as it is reported to be involved...

Full description

Bibliographic Details
Main Authors:	Abu, Nadiah, Mohamed, Nurul Elyani, Swee, Keong Yeap, Kian, Lam Lim, Akhtar, Muhammad Nadeem, Zulfadli, Aimi Jamil, Beh, Boon Kee, Abdullah, Mohd Puad, Omar, Abdul Rahman, Alitheen, Noorjahan Banu
Format:	Article
Language:	English
Published:	Dove Medical Press 2015
Online Access:	http://psasir.upm.edu.my/id/eprint/45115/ http://psasir.upm.edu.my/id/eprint/45115/1/FAVO.pdf

Similar Items

In vivo Antitumour and Antimetastic effects of Flavokawain B in 4T1 Breast Cancer Cell Challenged Mice
by: Akhtar, Muhammad Nadeem, et al.
Published: (2014)

In vitro Toxicity and in vivo Immunomodulatory Effects of Favokawain A and Flavokawain B in Balb/C Mice
by: Akhtar, Muhammad Nadeem, et al.
Published: (2014)

The Flavokawains: Uprising Medicinal Chalcones
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)

The flavokawains: uprising medicinal chalcones
by: Abu, Nadiah, et al.
Published: (2013)

The growth inhibitory potential and antimetastatic effect of camel urine on breast cancer cells in vitro and in vivo
by: Romli, Muhammad Firdaus, et al.
Published: (2017)

Flavokawain A Induces Apoptosis in MCF-7 and MDAMB231 and Inhibits the Metastatic Process In Vitro
by: Akhtar, Muhammad Nadeem, et al.

Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro
by: Nadiah, Abu, et al.
Published: (2014)

The antimetastatic and antiangiogenesis effects of kefir water on murine breast cancer cells
by: Zamberi, Nur Rizi, et al.
Published: (2016)

Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro
by: Abu, Nadiah, et al.
Published: (2014)

Bromelain enhances the anti-tumor effects of cisplatin on 4T1 breast tumor model in vivo
by: Mohamad, Nurul Elyani, et al.
Published: (2019)

Gene Expression Analysis Reveals the Concurrent Activation of Proapoptotic and Antioxidant-Defensive Mechanisms in Flavokawain B-Treated Cervical Cancer HeLa Cells
by: Swee, Keong Yeap, et al.
Published: (2017)

Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases in vitro
by: Abu, Nadiah, et al.
Published: (2016)

Antitumor and anti-metastatic effects of citral loaded nanostructured lipid carrier in 4T1 induced breast cancer mouse model
by: Nordin, Noraini, et al.
Published: (2020)

Flavokawain Derivative FLS Induced G2/M Arrest and Apoptosis on Breast Cancer MCF-7 Cell Line
by: Norlaily, Mohd Ali, et al.
Published: (2016)

Gene expression analysis reveals the concurrent activation of proapoptotic and antioxidant-defensive mechanisms in flavokawain B-treated cervical cancer HeLa cells
by: Yeap, Swee Keong, et al.
Published: (2017)

Flavokawain B Induced cytotoxicity in Two Breast Cancer Cell Lines, MCF-7 and MDA-MB231 and Inhibited the Metastatic Potential of MDA-MB231 via the Regulation of Several Tyrosine Kinases In vitro
by: Nadiah, Abu, et al.
Published: (2016)

In vivo hypocholesterolemic effect of MARDI fermented red yeast rice water extract in high cholesterol diet fed mice
by: Yeap, Swee Keong, et al.
Published: (2014)

In vitro antioxidant and in vivo hepatoprotective effect on ethanol-mediated liver damage of spray dried Vernonia amygdalina water extract
by: Ho, Wan Yong, et al.
Published: (2015)

Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines
by: Addila, Abu Bakar, et al.
Published: (2018)

Design, synthesis and docking studies of Flavokawain B type chalcones and their cytotoxic effects on MCF-7 and MDA-MB-231 cell lines
by: Abu Bakar, Addila, et al.
Published: (2018)

Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice
by: Mohammed Alitheen, Noorjahan Banu, et al.
Published: (2018)

3-Bromo-1-Hydroxy-9,10-Anthraquinone (BHAQ) Inhibits Growth and Migration of the Human Breast Cancer Cell Lines MCF-7 and MDA-MB231
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)

In vivo antidiabetic and acute toxicity of spray-dried Vernonia amygdalina water extract
by: Yeap, Swee Keong, et al.
Published: (2013)

Chemopreventive and immunomodulatory effects of Murraya koenigii aqueous extract on 4T1 breast cancer cell-challenged mice
by: Yeap, Swee Keong, et al.
Published: (2015)

Antitumor and Immunopotentiating Activity of Polysaccharide PST001 Isolated from the Seed Kernel of Tamarindus indica: An InVivo Study inMice
by: Aravind, S. R., et al.
Published: (2012)

3-bromo-1-hydroxy-9,10-anthraquinone (BHAQ) inhibits growth and migration of the human breast cancer cell lines MCF-7 and MDA-MB231
by: Abu, Nadiah, et al.
Published: (2013)

Immunomodulatory effect of Rhaphidophora korthalsii on mice splenocyte, thymocyte and bone marrow cell proliferation and cytokine expression
by: Yeap, Swee Keong, et al.
Published: (2011)

Immunomodulatory effects of Potentilla indica and Dendrophthoe pentandra on mice splenocytes and thymocytes
by: Ang, Hui Ying, et al.
Published: (2014)

Antistress and antioxidant effects of virgin coconut oil in vivo
by: Swee, Keong Yeap, et al.
Published: (2015)

Comparison of in vivo toxicity, antioxidant and immunomodulatory activities of coconut, nipah and pineapple juice vinegars
by: Mohamad, Nurul Elyani, et al.
Published: (2018)

In vivo antistress and antioxidant effects of fermented and germinated mung bean
by: Yeap, Swee Keong, et al.
Published: (2014)

In vivo immunomodulation and lipid peroxidation activities contributed to chemoprevention effects of fermented mung bean against breast cancer
by: Yeap, Swee Keong, et al.
Published: (2013)

In vitro and in vivo anti-tumour effects of coconut water vinegar on 4T1 breast cancer cells
by: Mohamad, Nurul Elyani, et al.
Published: (2019)

Metagenomic and phytochemical analyses of kefir water and its subchronic toxicity study in BALB/c mice
by: Kumar, Muganti Rajah, et al.
Published: (2021)

Antitumor and antioxidant effects of Clinacanthus nutans Lindau in 4T1 tumor-bearing mice
by: Nik Abd Rahman, Nik Mohd Afizan, et al.
Published: (2019)

Antioxidant effects of pineapple vinegar in reversing of paracetamol-induced liver damage in mice
by: Mohamad, Nurul Elyani, et al.
Published: (2015)

Design, synthesis and cytotoxic effects of curcumin derivatives on K562, MCF-7 and MDA-MB-231 cancer cell lines
by: Akhtar, Muhammad Nadeem, et al.
Published: (2018)

The In Vivo Anti-Tumor Effect of Curcumin Derivative (2E,6E)-2,6-bis(4-hydroxy-3-methoxybenzylidene) Cyclohexanone (BHMC) on 4T1 Breast Cancer Cells
by: Nursyamirah, Abd Razak, et al.
Published: (2017)

Infection with very virulent infectious bursal disease virus causes infiltration of t cells into bursa of fabricius
by: Jamil, Aimi Zulfadli, et al.
Published: (2013)

In vivo tumor targeting and anti-tumor effects of 5-fluororacil loaded, folic acid targeted quantum dot system
by: Bwatanglang, Ibrahim Birma, et al.
Published: (2016)