Supercritical carbon dioxide (SC-CO2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (Mentha spicata L.) leaves
In this study, supercritical carbon dioxide (SC-CO2) extraction conditions were optimized for the simultaneous separation of four bioactive flavonoids (catechin, CA; epicatechin, EP; rutin, RU; luteolin, LU) contained in spearmint (Mentha spicata L.) leaves. SC-CO2 extraction parameters such as pres...
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| Format: | Article |
| Language: | English |
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IDOSI Publications
2008
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| Online Access: | http://psasir.upm.edu.my/id/eprint/44448/ http://psasir.upm.edu.my/id/eprint/44448/1/Supercritical%20carbon%20dioxide%20%28SC-CO2%29%20extraction%20of%20catechin%2C%20epicatechin%2C%20rutin%20and%20luteolin%20from%20spearmint%20%28Mentha%20spicata%20L.%29%20leaves.pdf |
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| author | Bimakr, Mandana Abdul Rahman, Russly Taip, Farah Saleena Ling, Tau Chuan Ganjloo, Ali Md Salleh, Liza Selamat, Jinap Abdul Hamid, Azizah |
| author_facet | Bimakr, Mandana Abdul Rahman, Russly Taip, Farah Saleena Ling, Tau Chuan Ganjloo, Ali Md Salleh, Liza Selamat, Jinap Abdul Hamid, Azizah |
| author_sort | Bimakr, Mandana |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | In this study, supercritical carbon dioxide (SC-CO2) extraction conditions were optimized for the simultaneous separation of four bioactive flavonoids (catechin, CA; epicatechin, EP; rutin, RU; luteolin, LU) contained in spearmint (Mentha spicata L.) leaves. SC-CO2 extraction parameters such as pressure, temperature and dynamic extraction time were optimized by Complete Randomize Design (CRD) full factorial. The optimum condition of SC-CO2 extraction was achieved at 200 bar, 60°C and 60 min (with 60.566 mg/g extraction yield). Extracted yield at optimum condition was then analyzed by high performance liquid chromatography (HPLC) for quantifying bioactive flavonoid compounds. At optimum conditions, four bioactive flavonoids including (+)-catechin, (-)-epicatechin, rutin and luteolin were detected at high concentration. Luteolin (0.657 mg/g) had the highest concentration among the other detected flavonoids. The results indicated that SC-CO2 extraction is a promising and alternative process for recovering the bioactive compounds from spearmint leaves. |
| first_indexed | 2025-11-15T10:06:19Z |
| format | Article |
| id | upm-44448 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:06:19Z |
| publishDate | 2008 |
| publisher | IDOSI Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-444482020-08-04T02:19:45Z http://psasir.upm.edu.my/id/eprint/44448/ Supercritical carbon dioxide (SC-CO2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (Mentha spicata L.) leaves Bimakr, Mandana Abdul Rahman, Russly Taip, Farah Saleena Ling, Tau Chuan Ganjloo, Ali Md Salleh, Liza Selamat, Jinap Abdul Hamid, Azizah In this study, supercritical carbon dioxide (SC-CO2) extraction conditions were optimized for the simultaneous separation of four bioactive flavonoids (catechin, CA; epicatechin, EP; rutin, RU; luteolin, LU) contained in spearmint (Mentha spicata L.) leaves. SC-CO2 extraction parameters such as pressure, temperature and dynamic extraction time were optimized by Complete Randomize Design (CRD) full factorial. The optimum condition of SC-CO2 extraction was achieved at 200 bar, 60°C and 60 min (with 60.566 mg/g extraction yield). Extracted yield at optimum condition was then analyzed by high performance liquid chromatography (HPLC) for quantifying bioactive flavonoid compounds. At optimum conditions, four bioactive flavonoids including (+)-catechin, (-)-epicatechin, rutin and luteolin were detected at high concentration. Luteolin (0.657 mg/g) had the highest concentration among the other detected flavonoids. The results indicated that SC-CO2 extraction is a promising and alternative process for recovering the bioactive compounds from spearmint leaves. IDOSI Publications 2008 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/44448/1/Supercritical%20carbon%20dioxide%20%28SC-CO2%29%20extraction%20of%20catechin%2C%20epicatechin%2C%20rutin%20and%20luteolin%20from%20spearmint%20%28Mentha%20spicata%20L.%29%20leaves.pdf Bimakr, Mandana and Abdul Rahman, Russly and Taip, Farah Saleena and Ling, Tau Chuan and Ganjloo, Ali and Md Salleh, Liza and Selamat, Jinap and Abdul Hamid, Azizah (2008) Supercritical carbon dioxide (SC-CO2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (Mentha spicata L.) leaves. World Applied Sciences Journal, 5 (4). pp. 410-417. ISSN 1818-4952; ESSN: 1991-6426 https://www.idosi.org/wasj/wasj5(4)2008.htm |
| spellingShingle | Bimakr, Mandana Abdul Rahman, Russly Taip, Farah Saleena Ling, Tau Chuan Ganjloo, Ali Md Salleh, Liza Selamat, Jinap Abdul Hamid, Azizah Supercritical carbon dioxide (SC-CO2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (Mentha spicata L.) leaves |
| title | Supercritical carbon dioxide (SC-CO2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (Mentha spicata L.) leaves |
| title_full | Supercritical carbon dioxide (SC-CO2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (Mentha spicata L.) leaves |
| title_fullStr | Supercritical carbon dioxide (SC-CO2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (Mentha spicata L.) leaves |
| title_full_unstemmed | Supercritical carbon dioxide (SC-CO2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (Mentha spicata L.) leaves |
| title_short | Supercritical carbon dioxide (SC-CO2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (Mentha spicata L.) leaves |
| title_sort | supercritical carbon dioxide (sc-co2) extraction of catechin, epicatechin, rutin and luteolin from spearmint (mentha spicata l.) leaves |
| url | http://psasir.upm.edu.my/id/eprint/44448/ http://psasir.upm.edu.my/id/eprint/44448/ http://psasir.upm.edu.my/id/eprint/44448/1/Supercritical%20carbon%20dioxide%20%28SC-CO2%29%20extraction%20of%20catechin%2C%20epicatechin%2C%20rutin%20and%20luteolin%20from%20spearmint%20%28Mentha%20spicata%20L.%29%20leaves.pdf |