Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats
Brewers’ rice, which is known locally as temukut, is a mixture of broken rice, rice bran, and rice germ. Our present study was designed to identify the effect of brewers’ rice on the attenuation of liver and kidney damage induced by azoxymethane (AOM). Alanine transaminase (ALT), alkaline phosphatas...
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| Format: | Article |
| Language: | English |
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Hindawi
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/43973/ http://psasir.upm.edu.my/id/eprint/43973/1/Brewers%20rice%20a%20by-product%20from%20rice%20processing%20provides%20natural%20hepatorenal%20protection%20in%20azoxymethane-induced%20oxidative%20stress%20in%20rats.pdf |
| _version_ | 1848850373071077376 |
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| author | Mohd Esa, Norhaizan Tan, Bee Ling Ithnin, Hairuszah Hamzah, Hazilawati Karim, Roselina |
| author_facet | Mohd Esa, Norhaizan Tan, Bee Ling Ithnin, Hairuszah Hamzah, Hazilawati Karim, Roselina |
| author_sort | Mohd Esa, Norhaizan |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Brewers’ rice, which is known locally as temukut, is a mixture of broken rice, rice bran, and rice germ. Our present study was designed to identify the effect of brewers’ rice on the attenuation of liver and kidney damage induced by azoxymethane (AOM). Alanine transaminase (ALT), alkaline phosphatase (ALP), aspartate transaminase (AST), creatinine, and urea were evaluated to understand potential hepatoprotective effects and the ability of brewers’ rice to attenuate kidney pathology induced by AOM treatment. Liver and kidney tissues were evaluated by hematoxylin and eosin (H&E) staining. Overall analyses revealed that brewers’ rice improved the levels of serum markers in a manner associated with better histopathological outcomes, which indicated that brewers’ rice could enhance recovery from hepatocyte and kidney damage. Taken together, these results suggest that brewers’ rice could be used in future applications to combat liver and kidney disease. |
| first_indexed | 2025-11-15T10:05:15Z |
| format | Article |
| id | upm-43973 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:05:15Z |
| publishDate | 2015 |
| publisher | Hindawi |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-439732021-12-01T07:01:48Z http://psasir.upm.edu.my/id/eprint/43973/ Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats Mohd Esa, Norhaizan Tan, Bee Ling Ithnin, Hairuszah Hamzah, Hazilawati Karim, Roselina Brewers’ rice, which is known locally as temukut, is a mixture of broken rice, rice bran, and rice germ. Our present study was designed to identify the effect of brewers’ rice on the attenuation of liver and kidney damage induced by azoxymethane (AOM). Alanine transaminase (ALT), alkaline phosphatase (ALP), aspartate transaminase (AST), creatinine, and urea were evaluated to understand potential hepatoprotective effects and the ability of brewers’ rice to attenuate kidney pathology induced by AOM treatment. Liver and kidney tissues were evaluated by hematoxylin and eosin (H&E) staining. Overall analyses revealed that brewers’ rice improved the levels of serum markers in a manner associated with better histopathological outcomes, which indicated that brewers’ rice could enhance recovery from hepatocyte and kidney damage. Taken together, these results suggest that brewers’ rice could be used in future applications to combat liver and kidney disease. Hindawi 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/43973/1/Brewers%20rice%20a%20by-product%20from%20rice%20processing%20provides%20natural%20hepatorenal%20protection%20in%20azoxymethane-induced%20oxidative%20stress%20in%20rats.pdf Mohd Esa, Norhaizan and Tan, Bee Ling and Ithnin, Hairuszah and Hamzah, Hazilawati and Karim, Roselina (2015) Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats. Oxidative Medicine and Cellular Longevity, 2015. art. no. 539798. pp. 1-10. ISSN 1942-0900; ESSN: 1942-0994 https://www.hindawi.com/journals/omcl/2015/539798/ 10.1155/2015/539798 |
| spellingShingle | Mohd Esa, Norhaizan Tan, Bee Ling Ithnin, Hairuszah Hamzah, Hazilawati Karim, Roselina Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats |
| title | Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats |
| title_full | Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats |
| title_fullStr | Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats |
| title_full_unstemmed | Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats |
| title_short | Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats |
| title_sort | brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats |
| url | http://psasir.upm.edu.my/id/eprint/43973/ http://psasir.upm.edu.my/id/eprint/43973/ http://psasir.upm.edu.my/id/eprint/43973/ http://psasir.upm.edu.my/id/eprint/43973/1/Brewers%20rice%20a%20by-product%20from%20rice%20processing%20provides%20natural%20hepatorenal%20protection%20in%20azoxymethane-induced%20oxidative%20stress%20in%20rats.pdf |