Bixa orellana leaf extract suppress histamine-induced endothelial hyperpermeability via the PLC-NO-cGMP signaling cascade

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Bixa orellana leaf extract suppress histamine-induced endothelial hyperpermeability via the PLC-NO-cGMP signaling cascade

Background: Histamine is established as a potent inflammatory mediator and it is known to increased endothelial permeability by promoting gap formation between endothelial cells. Previous studies have shown that aqueous extract of Bixa orellana leaves (AEBO) exhibits antihistamine activity in vivo,...

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Bibliographic Details
Main Authors:	Yong, Yoke Keong, Abdullah, Muhammad Nazrul Hakim, Ahmad, Zuraini
Format:	Article
Language:	English
Published:	BMC 2015
Online Access:	http://psasir.upm.edu.my/id/eprint/43955/ http://psasir.upm.edu.my/id/eprint/43955/1/Bixa%20orellana%20leaf%20extract%20suppress%20histamine-induced%20endothelial%20hyperpermeability%20via%20the%20PLC-NO-cGMP%20signaling%20cascade.pdf

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