Assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (IL-6)
Aims: To determine the respiratory inflammation among children living near to non-sanitary municipal solid waste landfill area and the concentration of Interleukin-6 cytokine. Study Design: A cross-sectional comparative study design. Place and Duration of Study: Sample: Pajam, Negeri Sembilan, Mal...
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| Format: | Article |
| Language: | English |
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SCIENCEDOMAIN International
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/43844/ http://psasir.upm.edu.my/id/eprint/43844/1/Assessing%20Respiratory%20Inflammation%20among.pdf |
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| author | Syed Ismail, Sharifah Norkhadijah Othman, Muhammad S. Jamaluddin, Dora E. Praveena, Sarva Mangala Ho, Yu Bin Zainal Abidin, Emilia A. Wahab, Aini Syuhaida A., Haryati |
| author_facet | Syed Ismail, Sharifah Norkhadijah Othman, Muhammad S. Jamaluddin, Dora E. Praveena, Sarva Mangala Ho, Yu Bin Zainal Abidin, Emilia A. Wahab, Aini Syuhaida A., Haryati |
| author_sort | Syed Ismail, Sharifah Norkhadijah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Aims: To determine the respiratory inflammation among children living near to non-sanitary municipal solid waste landfill area and the concentration of Interleukin-6 cytokine.
Study Design: A cross-sectional comparative study design.
Place and Duration of Study: Sample: Pajam, Negeri Sembilan, Malaysia, between September 2013 and April 2014.
Methodology: A total of 72 children were randomly selected based on the inclusive and exclusive criteria. A set of pre-tested questionnaires were utilized to obtain socio-demographic information and to predict health risk faced by the respondents. Saliva samples of the respondents were collected and analyzed using Human Interleukin-6 (IL-6) Platinum ELISA (Enzyme-Linked Immunosorbent Assay) kit.
Results: The PM10 concentration for the exposed group was higher than the unexposed group with the mean ± standard deviation (SD) of 152.31±31.07 μg/m3 and 87.77±30.77 μg/m3 respectively. The mean ± SD of the Interleukin-6 for the exposed group was slightly higher than the unexposed group with the mean ± SD of 6.34±1.95 pg/ml and 5.77±1.08 pg/ml respectively. The most common symptoms reported was sneezing and sore throat. There was no significant correlation between PM10 concentration and IL-6 in this study.
Conclusion: The findings exhibit that there was no association between Interleukin-6 and PM10 concentration of the respondent. However, there are likely potential adverse health impacts arising from particulates exposure among exposed children in this study. Respondents are advised to have a medical check-up in order to determine respiratory health status thus elimination the risks of acquiring respiratory inflammation. |
| first_indexed | 2025-11-15T10:04:42Z |
| format | Article |
| id | upm-43844 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:04:42Z |
| publishDate | 2015 |
| publisher | SCIENCEDOMAIN International |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-438442016-10-26T08:44:38Z http://psasir.upm.edu.my/id/eprint/43844/ Assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (IL-6) Syed Ismail, Sharifah Norkhadijah Othman, Muhammad S. Jamaluddin, Dora E. Praveena, Sarva Mangala Ho, Yu Bin Zainal Abidin, Emilia A. Wahab, Aini Syuhaida A., Haryati Aims: To determine the respiratory inflammation among children living near to non-sanitary municipal solid waste landfill area and the concentration of Interleukin-6 cytokine. Study Design: A cross-sectional comparative study design. Place and Duration of Study: Sample: Pajam, Negeri Sembilan, Malaysia, between September 2013 and April 2014. Methodology: A total of 72 children were randomly selected based on the inclusive and exclusive criteria. A set of pre-tested questionnaires were utilized to obtain socio-demographic information and to predict health risk faced by the respondents. Saliva samples of the respondents were collected and analyzed using Human Interleukin-6 (IL-6) Platinum ELISA (Enzyme-Linked Immunosorbent Assay) kit. Results: The PM10 concentration for the exposed group was higher than the unexposed group with the mean ± standard deviation (SD) of 152.31±31.07 μg/m3 and 87.77±30.77 μg/m3 respectively. The mean ± SD of the Interleukin-6 for the exposed group was slightly higher than the unexposed group with the mean ± SD of 6.34±1.95 pg/ml and 5.77±1.08 pg/ml respectively. The most common symptoms reported was sneezing and sore throat. There was no significant correlation between PM10 concentration and IL-6 in this study. Conclusion: The findings exhibit that there was no association between Interleukin-6 and PM10 concentration of the respondent. However, there are likely potential adverse health impacts arising from particulates exposure among exposed children in this study. Respondents are advised to have a medical check-up in order to determine respiratory health status thus elimination the risks of acquiring respiratory inflammation. SCIENCEDOMAIN International 2015 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/43844/1/Assessing%20Respiratory%20Inflammation%20among.pdf Syed Ismail, Sharifah Norkhadijah and Othman, Muhammad S. and Jamaluddin, Dora E. and Praveena, Sarva Mangala and Ho, Yu Bin and Zainal Abidin, Emilia and A. Wahab, Aini Syuhaida and A., Haryati (2015) Assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (IL-6). Advances in Research, 3 (4). pp. 404-416. ISSN 2348-0394 http://www.sciencedomain.org 10.9734/AIR/2015/14478 |
| spellingShingle | Syed Ismail, Sharifah Norkhadijah Othman, Muhammad S. Jamaluddin, Dora E. Praveena, Sarva Mangala Ho, Yu Bin Zainal Abidin, Emilia A. Wahab, Aini Syuhaida A., Haryati Assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (IL-6) |
| title | Assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (IL-6) |
| title_full | Assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (IL-6) |
| title_fullStr | Assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (IL-6) |
| title_full_unstemmed | Assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (IL-6) |
| title_short | Assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (IL-6) |
| title_sort | assessing respiratory inflammation among children living near to non-sanitary landfill using interleukin-6 (il-6) |
| url | http://psasir.upm.edu.my/id/eprint/43844/ http://psasir.upm.edu.my/id/eprint/43844/ http://psasir.upm.edu.my/id/eprint/43844/ http://psasir.upm.edu.my/id/eprint/43844/1/Assessing%20Respiratory%20Inflammation%20among.pdf |