Are bioactive-rich fractions functionally richer?

Plant bioresources are relied upon as natural, inexpensive, and sustainable remedies for the management of several chronic diseases worldwide. Plants have historically been consumed for medicinal purposes based on traditional belief, but this trend is currently changing. The growing interest in the...

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Main Authors: Imam, Mustapha Umar, Ismail, Maznah, Der, Jiun Ooi, Azmi, Nur Hanisah, Sarega, Nadarajan, Kim, Wei Chan, Bhanger, Muhammad Iqbal
Format: Article
Language:English
Published: Informa Healthcare USA 2016
Online Access:http://psasir.upm.edu.my/id/eprint/43830/
http://psasir.upm.edu.my/id/eprint/43830/1/Are%20bioactive-rich%20fractions%20functionally%20richer.docx.pdf
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author Imam, Mustapha Umar
Ismail, Maznah
Der, Jiun Ooi
Azmi, Nur Hanisah
Sarega, Nadarajan
Kim, Wei Chan
Bhanger, Muhammad Iqbal
author_facet Imam, Mustapha Umar
Ismail, Maznah
Der, Jiun Ooi
Azmi, Nur Hanisah
Sarega, Nadarajan
Kim, Wei Chan
Bhanger, Muhammad Iqbal
author_sort Imam, Mustapha Umar
building UPM Institutional Repository
collection Online Access
description Plant bioresources are relied upon as natural, inexpensive, and sustainable remedies for the management of several chronic diseases worldwide. Plants have historically been consumed for medicinal purposes based on traditional belief, but this trend is currently changing. The growing interest in the medicinal properties of plant bioresources stems from concerns of side effects and other adverse effects caused by synthetic drugs. This interest has yielded a better understanding of the roles of plant bioactive compounds in health promotion and disease prevention, including the underlying mechanisms involved in such functional effects. The desire to maximize the potential of phytochemicals has led to the development of "rich fractions," in which extracts contain bioactive compounds in addition to elevated levels of the primary compound. Although a rich fraction effectively increases the bioactivity of the extract, the standardization and quality assurance process can be challenging. However, the supercritical fluid extraction (SFE) system is a promising green technology in this regard. Future clinical and pharmacological studies are needed to fully elucidate the implications of these preparations in the management of human diseases, thereby fostering a move toward evidence-based medicine.
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spelling upm-438302020-04-15T16:54:51Z http://psasir.upm.edu.my/id/eprint/43830/ Are bioactive-rich fractions functionally richer? Imam, Mustapha Umar Ismail, Maznah Der, Jiun Ooi Azmi, Nur Hanisah Sarega, Nadarajan Kim, Wei Chan Bhanger, Muhammad Iqbal Plant bioresources are relied upon as natural, inexpensive, and sustainable remedies for the management of several chronic diseases worldwide. Plants have historically been consumed for medicinal purposes based on traditional belief, but this trend is currently changing. The growing interest in the medicinal properties of plant bioresources stems from concerns of side effects and other adverse effects caused by synthetic drugs. This interest has yielded a better understanding of the roles of plant bioactive compounds in health promotion and disease prevention, including the underlying mechanisms involved in such functional effects. The desire to maximize the potential of phytochemicals has led to the development of "rich fractions," in which extracts contain bioactive compounds in addition to elevated levels of the primary compound. Although a rich fraction effectively increases the bioactivity of the extract, the standardization and quality assurance process can be challenging. However, the supercritical fluid extraction (SFE) system is a promising green technology in this regard. Future clinical and pharmacological studies are needed to fully elucidate the implications of these preparations in the management of human diseases, thereby fostering a move toward evidence-based medicine. Informa Healthcare USA 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/43830/1/Are%20bioactive-rich%20fractions%20functionally%20richer.docx.pdf Imam, Mustapha Umar and Ismail, Maznah and Der, Jiun Ooi and Azmi, Nur Hanisah and Sarega, Nadarajan and Kim, Wei Chan and Bhanger, Muhammad Iqbal (2016) Are bioactive-rich fractions functionally richer? Critical Reviews in Biotechnology, 36 (2). pp. 585-593. ISSN 0738-8551; ESSN: 1549-7801 10.3109/07388551.2014.995586
spellingShingle Imam, Mustapha Umar
Ismail, Maznah
Der, Jiun Ooi
Azmi, Nur Hanisah
Sarega, Nadarajan
Kim, Wei Chan
Bhanger, Muhammad Iqbal
Are bioactive-rich fractions functionally richer?
title Are bioactive-rich fractions functionally richer?
title_full Are bioactive-rich fractions functionally richer?
title_fullStr Are bioactive-rich fractions functionally richer?
title_full_unstemmed Are bioactive-rich fractions functionally richer?
title_short Are bioactive-rich fractions functionally richer?
title_sort are bioactive-rich fractions functionally richer?
url http://psasir.upm.edu.my/id/eprint/43830/
http://psasir.upm.edu.my/id/eprint/43830/
http://psasir.upm.edu.my/id/eprint/43830/1/Are%20bioactive-rich%20fractions%20functionally%20richer.docx.pdf