Antiviral activity of resveratrol against human and animal viruses
Resveratrol is a potent polyphenolic compound that is being extensively studied in the amelioration of viral infections both in vitro and in vivo. Its antioxidant effect is mainly elicited through inhibition of important gene pathways like the NF-κβ pathway, while its antiviral effects are associate...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Hindawi Publishing Corporation
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/43808/ http://psasir.upm.edu.my/id/eprint/43808/1/Antiviral%20Activity%20of%20Resveratrol%20against%20Human.pdf |
| _version_ | 1848850328479334400 |
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| author | Abba, Yusuf Hassim, Hasliza Hamzah, Hazilawati Mohamed Mustapha, Noordin |
| author_facet | Abba, Yusuf Hassim, Hasliza Hamzah, Hazilawati Mohamed Mustapha, Noordin |
| author_sort | Abba, Yusuf |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Resveratrol is a potent polyphenolic compound that is being extensively studied in the amelioration of viral infections both in vitro and in vivo. Its antioxidant effect is mainly elicited through inhibition of important gene pathways like the NF-κβ pathway, while its antiviral effects are associated with inhibitions of viral replication, protein synthesis, gene expression, and nucleic acid synthesis. Although the beneficial roles of resveratrol in several viral diseases have been well documented, a few adverse effects have been reported as well. This review highlights the antiviral mechanisms of resveratrol in human and animal viral infections and how some of these effects are associated with the antioxidant properties of the compound. |
| first_indexed | 2025-11-15T10:04:33Z |
| format | Article |
| id | upm-43808 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T10:04:33Z |
| publishDate | 2015 |
| publisher | Hindawi Publishing Corporation |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-438082016-11-21T05:10:17Z http://psasir.upm.edu.my/id/eprint/43808/ Antiviral activity of resveratrol against human and animal viruses Abba, Yusuf Hassim, Hasliza Hamzah, Hazilawati Mohamed Mustapha, Noordin Resveratrol is a potent polyphenolic compound that is being extensively studied in the amelioration of viral infections both in vitro and in vivo. Its antioxidant effect is mainly elicited through inhibition of important gene pathways like the NF-κβ pathway, while its antiviral effects are associated with inhibitions of viral replication, protein synthesis, gene expression, and nucleic acid synthesis. Although the beneficial roles of resveratrol in several viral diseases have been well documented, a few adverse effects have been reported as well. This review highlights the antiviral mechanisms of resveratrol in human and animal viral infections and how some of these effects are associated with the antioxidant properties of the compound. Hindawi Publishing Corporation 2015 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/43808/1/Antiviral%20Activity%20of%20Resveratrol%20against%20Human.pdf Abba, Yusuf and Hassim, Hasliza and Hamzah, Hazilawati and Mohamed Mustapha, Noordin (2015) Antiviral activity of resveratrol against human and animal viruses. Advances in Virology, 2015. art. no. 184241. pp. 1-7. ISSN 1687-8639; ESSN: 1687-8647 http://www.hindawi.com/journals/av/2015/184241/ 10.1155/2015/184241 |
| spellingShingle | Abba, Yusuf Hassim, Hasliza Hamzah, Hazilawati Mohamed Mustapha, Noordin Antiviral activity of resveratrol against human and animal viruses |
| title | Antiviral activity of resveratrol against human and animal viruses |
| title_full | Antiviral activity of resveratrol against human and animal viruses |
| title_fullStr | Antiviral activity of resveratrol against human and animal viruses |
| title_full_unstemmed | Antiviral activity of resveratrol against human and animal viruses |
| title_short | Antiviral activity of resveratrol against human and animal viruses |
| title_sort | antiviral activity of resveratrol against human and animal viruses |
| url | http://psasir.upm.edu.my/id/eprint/43808/ http://psasir.upm.edu.my/id/eprint/43808/ http://psasir.upm.edu.my/id/eprint/43808/ http://psasir.upm.edu.my/id/eprint/43808/1/Antiviral%20Activity%20of%20Resveratrol%20against%20Human.pdf |