Anti-proliferative effect and induction of apoptosis in androgen-independent human prostate cancer cells by 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one
Curcumin has poor in vivo absorption and bioavailability, highlighting a need for new curcumin analogues with better characteristics in these aspects. The aim of this study is to determine the anti-cancer properties of four selected curcumin analogues, on the cytotoxicity, proliferative and apoptoti...
| Main Authors: | Citalingam, Kamini, Abas, Faridah, Lajis, Nordin H., Othman, Iekhsan, Naidu, Rakesh |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI
2015
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/43804/ http://psasir.upm.edu.my/id/eprint/43804/1/Anti-Proliferative%20Effect%20and%20Induction%20of%20Apoptosis%20in.pdf |
Similar Items
Diarylpentanoid (1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one) (MS13) exhibits anti-proliferative, apoptosis induction and anti-migration properties on androgen-independent human prostate cancer by targeting cell cycle-apoptosis and PI3K signalling pathways
by: Abd Wahab, Nurul Azwa, et al.
Published: (2021)
by: Abd Wahab, Nurul Azwa, et al.
Published: (2021)
Mechanism of anti-cancer activity of curcumin on androgen-dependent and androgen-independent prostate cancer
by: Abd. Wahab, Nurul Azwa, et al.
Published: (2020)
by: Abd. Wahab, Nurul Azwa, et al.
Published: (2020)
The curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one induces apoptosis and downregulates E6 and E7 oncogene expression in HPV16 and HPV18-infected cervical cancer cells
by: Paulraj, Felicia, et al.
Published: (2015)
by: Paulraj, Felicia, et al.
Published: (2015)
Identification of commonly regulated genes in HPV18- and HPV16-infected cervical cancer cells treated with the curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one
by: Paulraj, Felicia, et al.
Published: (2018)
by: Paulraj, Felicia, et al.
Published: (2018)
Anti-cancer mechanisms of diarylpentanoid MS17 (1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one) in human colon cancer cells: a proteomics approach
by: Hon, Kha Wai, et al.
Published: (2024)
by: Hon, Kha Wai, et al.
Published: (2024)
Molecular mechanisms of antiproliferative and apoptosis activity by 1,5-bis(4-hydroxy-3 methoxyphenyl) 1,4-pentadiene-3-one (ms13) on human non-small cell lung cancer cells
by: Wan Mohd Tajuddin, Wan Nur Baitty, et al.
Published: (2021)
by: Wan Mohd Tajuddin, Wan Nur Baitty, et al.
Published: (2021)
1,5-Bis[(E)-1-(2-hydroxyphenyl)ethylidene]thiocarbonohydrazide
monohydrate
by: Fasihuddin B, Ahmad, et al.
Published: (2010)
by: Fasihuddin B, Ahmad, et al.
Published: (2010)
Epigenetic coregulators of androgen signalling in prostate cancer
by: Metzler, Veronika
Published: (2020)
by: Metzler, Veronika
Published: (2020)
Effects of Payena dasyphylla (miq.) on hyaluronidase activity and metalloproteinases expression in interleukin-1B stimulated human chondrocytes cells
by: Citalingam, Kamini
Published: (2012)
by: Citalingam, Kamini
Published: (2012)
Mechanism of apoptosis induced by curcumin in colorectal cancer
by: Ismail, Nor Isnida, et al.
Published: (2019)
by: Ismail, Nor Isnida, et al.
Published: (2019)
3,5-Bis(4-hydroxyphenyl)-4H-1,2,4-triazol-4-amine monohydrate
by: Silong, Sidik, et al.
Published: (2010)
by: Silong, Sidik, et al.
Published: (2010)
Targeting androgen receptor and PIP5K1A in prostate cancer cells using CRISPR-Cas9 genome editing tool
by: Hernández-Quiles, Miguel
Published: (2017)
by: Hernández-Quiles, Miguel
Published: (2017)
Crystal structure of 3-(2-hydroxyphenyl)-1-(2’-hydroxyphenyl)-2-propen-1-one, C15H12O3
by: M-C, Feng, et al.
Published: (1999)
by: M-C, Feng, et al.
Published: (1999)
(3E)-3-(4-(Dimenthylamino)Phenyl)-1-(4-Hydroxyphenyl)Prop-2-En-1-One
by: Hasan, Aurangzeb, et al.
Published: (2010)
by: Hasan, Aurangzeb, et al.
Published: (2010)
Crystal structure of E-1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)-2-propen-1-one, C15H12O3
by: M-C, Feng, et al.
Published: (1999)
by: M-C, Feng, et al.
Published: (1999)
3-{(E)-[1-(2-Hydroxyphenyl)ethylidene]-amino}-1-(2-methylphenyl)thiourea
by: Abdus, Salam, et al.
Published: (2011)
by: Abdus, Salam, et al.
Published: (2011)
Androgens and the endometrium
by: Suri, Narinder K.
Published: (1988)
by: Suri, Narinder K.
Published: (1988)
(E)-1-(4-Decyloxyphenyl)-3-(4-hydroxyphenyl) prop-2-en-1-one
by: Ibrahim, Abdul Razak, et al.
Published: (2009)
by: Ibrahim, Abdul Razak, et al.
Published: (2009)
(E)-3-(4-Decyloxyphenyl)-1-(2-hydroxyphenyl) prop-2-en-1-one
by: Zainab, Ngaini, et al.
Published: (2009)
by: Zainab, Ngaini, et al.
Published: (2009)
3-(2-Hydroxyphenyl)-1-{(E)-[1-(pyrazin- 2-yl)ethylidene]amino}thiourea monohydrate
by: Abdullah, Erna Normaya, et al.
Published: (2011)
by: Abdullah, Erna Normaya, et al.
Published: (2011)
(E)-1-(3-Hydroxyphenyl)-3-[4-(tetradecyloxy) phenyl]prop-2-en-1-one
by: Siti Muhaini, Haris Fadzillah, et al.
Published: (2012)
by: Siti Muhaini, Haris Fadzillah, et al.
Published: (2012)
(E)-1-[4-(Hexyloxy)phenyl]-3-(2-hydroxyphenyl) prop-2-en-1-one
by: Siti Muhaini, Haris Fadzillah, et al.
Published: (2012)
by: Siti Muhaini, Haris Fadzillah, et al.
Published: (2012)
(E)-1-[4-(Hexyloxy)phenyl]-3-(3-hydroxyphenyl) prop-2-en-1-one
by: Zainab, Ngaini, et al.
Published: (2010)
by: Zainab, Ngaini, et al.
Published: (2010)
(E)-3-[4-(Decyloxy) phenyl]-1-(4-hydroxyphenyl) prop-2-en-1-one
by: Ibrahim, Abdul Razak, et al.
Published: (2009)
by: Ibrahim, Abdul Razak, et al.
Published: (2009)
Adverse effects to quality of life arising from treatment can recover with intermittent androgen suppression in men with prostate cancer.
by: Spry, N., et al.
Published: (2006)
by: Spry, N., et al.
Published: (2006)
Andrographolide induces cell cycle arrest and apoptosis in PC-3 prostate cancer cells.
by: Hui, Chyn Wong, et al.
Published: (2011)
by: Hui, Chyn Wong, et al.
Published: (2011)
Effects of Payena dasyphylla (Miq.) on Hyaluronidase Enzyme Activity and Metalloproteinases Protein Expressions in Interleukin-1β Stimulated Human Chondrocytes Cells
by: Kamini, Citalingam, et al.
Published: (2013)
by: Kamini, Citalingam, et al.
Published: (2013)
Effects of Payena dasyphylla (Miq.) on hyaluronidase enzyme activity and metalloproteinases protein expressions in interleukin-1beta stimulated human chondrocytes cells
by: Citalingam, Kamini, et al.
Published: (2013)
by: Citalingam, Kamini, et al.
Published: (2013)
Androgens And Cardiovascular Disease In Men
by: Yeap, B., et al.
Published: (2019)
by: Yeap, B., et al.
Published: (2019)
Dose related proliferative changes in the prostate of rats induced by eurycoma longifolia Jack (Tongkat Ali) extract
by: Faisal, Ghasak Ghazi, et al.
Published: (2014)
by: Faisal, Ghasak Ghazi, et al.
Published: (2014)
Zwitterionic 1-{(1E)-[(4-hydroxyphenyl)iminio]methyl}naphthalen-2-olate: crystal structure and Hirshfeld surface analysis
by: Devika, Bhai R., et al.
Published: (2017)
by: Devika, Bhai R., et al.
Published: (2017)
The amino-terminal domain of the androgen receptor co-opts extracellular signal-regulated kinase (ERK) docking sites in ELK1 protein to induce sustained gene activation that supports prostate cancer cell growth
by: Rosati, Rayna, et al.
Published: (2016)
by: Rosati, Rayna, et al.
Published: (2016)
(2E,2'E)-1,1'-(1,4-Phenylene)bis[3-(3-chlorophenyl)-
prop-2-en-1-one]
by: Rajendraprasad, S., et al.
Published: (2017)
by: Rajendraprasad, S., et al.
Published: (2017)
N′-[1-(5-Bromo-2-hydroxyphenyl)ethylidene]isonicotinohydrazide monohydrate: crystal structure and Hirshfeld surface analysis
by: Lee, See Mun *, et al.
Published: (2017)
by: Lee, See Mun *, et al.
Published: (2017)
2,2'-[2,5-Bis(hexyloxy)-1,4-phenylene]dithiophene
by: Teh, Chin Hoong, et al.
Published: (2012)
by: Teh, Chin Hoong, et al.
Published: (2012)
2,2'-[2,4-Bis(naphthalen-1-yl)cyclobutane-
1,3-diyl]bis(1-methylpyridinium)
bis(4-chlorobenzenesulfonate): thermalinduced
[2 + 2] cycloaddition reaction of
a heterostilbene
by: Chantrapromma, Suchada, et al.
Published: (2014)
by: Chantrapromma, Suchada, et al.
Published: (2014)
Analysis of glutathione S-transferase (M1, T1 and P1) gene polymorphisms in Iranian prostate cancer subjects
by: Basir, Sahar Ansari, et al.
Published: (2010)
by: Basir, Sahar Ansari, et al.
Published: (2010)
Synthesis, Characterization, and Liquid Crystalline Properties of Phosphazenes Incorporated (E)-3-(4-alkyloxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
by: Norashikin Irdawaty, Abd Rahman, et al.
Published: (2011)
by: Norashikin Irdawaty, Abd Rahman, et al.
Published: (2011)
Crystal structure of [μ2-1,1′-bis(diphenylphosphanyl)ferrocene-κ2P:P′]bis[(pyrrolidine-1-carbodithioato-κS)gold(I)]
by: Tan, Yee Seng *, et al.
Published: (2015)
by: Tan, Yee Seng *, et al.
Published: (2015)
Does exercise impact gut microbiota composition in men receiving androgen deprivation therapy for prostate cancer? A single-blinded, two-armed, randomised controlled trial
by: Newton, R.U., et al.
Published: (2019)
by: Newton, R.U., et al.
Published: (2019)
Similar Items
-
Diarylpentanoid (1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one) (MS13) exhibits anti-proliferative, apoptosis induction and anti-migration properties on androgen-independent human prostate cancer by targeting cell cycle-apoptosis and PI3K signalling pathways
by: Abd Wahab, Nurul Azwa, et al.
Published: (2021) -
Mechanism of anti-cancer activity of curcumin on androgen-dependent and androgen-independent prostate cancer
by: Abd. Wahab, Nurul Azwa, et al.
Published: (2020) -
The curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one induces apoptosis and downregulates E6 and E7 oncogene expression in HPV16 and HPV18-infected cervical cancer cells
by: Paulraj, Felicia, et al.
Published: (2015) -
Identification of commonly regulated genes in HPV18- and HPV16-infected cervical cancer cells treated with the curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one
by: Paulraj, Felicia, et al.
Published: (2018) -
Anti-cancer mechanisms of diarylpentanoid MS17 (1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one) in human colon cancer cells: a proteomics approach
by: Hon, Kha Wai, et al.
Published: (2024)