A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity

QR Code

A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity

Recent outbreaks of highly pathogenic and occasional drug-resistant influenza strains have highlighted the need to develop novel anti-influenza therapeutics. Here, we report computational and experimental efforts to identify influenza neuraminidase inhibitors from among the 3000 natural compounds in...

Full description

Bibliographic Details
Main Authors:	Khairul Ikram, Nur Kusaira, Durrant, Jacob D., Muchtaridi, M., Zalaludin, Ayunni Salihah, Purwitasari, Neny, Mohamed, Nornisah, Abdul Rahim, Aisyah Saad, Chan, Kit Lam, Mohd Yahaya, Normi, Abd Rahman, Noorsaadah, Amaro, Rommie E., A. Wahab, Habibah
Format:	Article
Language:	English
Published:	ACS Publications 2015
Online Access:	http://psasir.upm.edu.my/id/eprint/43627/ http://psasir.upm.edu.my/id/eprint/43627/1/123.pdf

Similar Items

Extraction And Isolation Of Chemical Compound From Tabernaemontana Divaricata (L.) R.Br. Ex Roem. & Schult. Leaves With Potential Anti-Neuraminidase Activity
by: Zalaludin, Ayunni Salihah
Published: (2015)

Neuraminidase Inhibition And In Vitro Anti Influenza A (H1n1) Activities Of Brucea Javanica (L.) Merr
by: Purwitasari, Neny
Published: (2013)

Computer-Aided Drug Design Of Potential Neuraminidase Inhibitors From Plant Extracts
by: Muchtaridi, Muchtaridi
Published: (2013)

Anti-inflammatory activity of Alpinia malaccensis (Burm. f.) roscoe and Kaempferia galanga L. rhizome essential oil gel formulations by carrageenan induction method
by: Muchtaridi, Muchtaridi, et al.
Published: (2022)

Identification Of Potential Neuraminidase Inhibitors Using Ensemble-Based Virtual Screening
by: Lim, Kok Keong
Published: (2013)

Potential Neuraminidase Inhibitors Via Virtual Screening, Kinetic Studies, And Adme Predictions
by: Nuwarda, Rina Fajri
Published: (2015)

Virtual High Throughput Screening For Avian Influenza (H5nl) Neuraminidase Inhibitors
by: Ismail, Nurul Izza
Published: (2011)

Neuraminidase inhibitors: who, when, where?
by: Nguyen-Van-Tam, Jonathan S., et al.
Published: (2015)

Neuraminidase inhibitors for influenza complications: authors' reply
by: Nguyen-Van-Tam, Jonathan S., et al.
Published: (2014)

In silico study of carvone derivatives as potential neuraminidase inhibitors
by: Jusoh, Noorakmar, et al.
Published: (2018)

Synthesis, neuraminidase inhibition assay and molecular docking of carvone derivatives
by: Abd Hamid, Shafida
Published: (2019)

Thermostability of the Recombinant Haemagglutinin-Neuraminidase Glycoproteins of Newcastle Disease Virus
by: Tang, Yik Kiong
Published: (2003)

Molecular Dynamics Studies Of The Effects Of Neuraminidase Mutation On Oseltamivir Resistance
by: Muhammad Yusuf, Muhammad Yusuf
Published: (2015)

Modelling And Syntheses Of Vanillin Derivatives Targeting Influenza Virus Neuraminidase
by: Asaruddin, Mohd Razip
Published: (2016)

Synthesis and molecular docking of carvone derivatives as a potential neuraminidase inhibitors
by: Jusoh, Noorakmar, et al.
Published: (2016)

Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality
by: Leonardi-Bee, Jo, et al.
Published: (2014)

Newcastle disease virus hemagglutinin neuraminidase as a potential cancer targeting agent
by: Baradaran, Ali, et al.
Published: (2016)

Evaluation Of Various Autodock Molecular Docking Programmes In Predicting The Neuraminidase Inhibitory Activity
by: Raime, Nurul Nadia
Published: (2015)

In-Vitro And Molecular Docking Studies Of Seven Selected Myrtaceae Plants For Neuraminidase Activity
by: Ali Abdusalsalam, Ashraf Ahmed
Published: (2016)

Thioguanine-based DENV-2 NS2B/NS3 protease inhibitors: Virtual screening, synthesis, biological evaluation and molecular modelling
by: Hariono, Maywan, et al.
Published: (2019)

Monoclonal antibodies against the haemagglutinin-neuraminidase glycoprotein of Newcastle disease virus strain AF2240
by: Lee, L. K., et al.
Published: (2007)

Rational Design And Synthesis Of Inhibitors For H1n1 Neuraminidase And Dengue Protease Enzymes
by: Hariono, Maywan
Published: (2015)

Impact of neuraminidase inhibitor treatment on hospitalisation in patients with pandemic influenza: a multi-method modelling approach
by: Venkatesan, Sudhir
Published: (2019)

Immunogenic properties of recombinant ectodomain of Newcastle disease virus hemagglutinin-neuraminidase protein expressed in Escherichia coli.
by: Wong, Sing King, et al.
Published: (2009)

Sequence of the haemagglutinin-neuraminidase gene of the Newcastle disease virus oral vaccine strain V4(UPM)
by: Yusoff, Khatijah, et al.
Published: (1996)

Cloning and Expression of the Haemagglutinin-neuraminidase Gene of Newcastle Disease Virus Strain Af2240 Lnto Eschericia Coli
by: Sudin, Sudani
Published: (1997)

Heterologous Expression Of Avian Influenza A (H5n1) Neuraminidase In Kluyveromyces Lactis And Escherichia Coli
by: Taufik, Noor Zafiah
Published: (2016)

Inhibitors of leishmania mexicana phosphoglycerate mutase identified by virtual screening and verified by inhibition studies
by: Ahmad Fuad, Fazia Adyani, et al.
Published: (2016)

Diverse approaches to learning with immersive virtual reality identified from a systematic review
by: Won, Mihye, et al.
Published: (2022)

Inhibitors of Leishmania mexicana phosphoglycerate mutase identified by virtual screening and verified by inhibition studies
by: Fazia Adyani Ahmad Fuad,, et al.
Published: (2016)

UMP virtual directory in augmented reality
by: Kit, Thium Keng
Published: (2013)

Use of neuraminidase inhibitors for rapid containment of influenza: a systematic review and meta-analysis of individual and household transmission studies
by: Okoli, G.N., et al.
Published: (2014)

Generation of a Panel of Monoclonal Antibodies Against the Haemagglutinin-Neuraminidase Glycoprotein of Newcastle Disease Virus Strain Af2240
by: Lee, Lin Kiat
Published: (2005)

Induction of apoptosis in MCF-7 cells by the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus Malaysian strain AF2240
by: Ghrici, Mohamed, et al.
Published: (2013)

Analogues of 2-Deoxyglucose as inhibitor candidates for hexokinase II identified via virtual screening analyses
by: Tanbin, Suriyea, et al.
Published: (2018)

Clinicians' attitude towards a placebo-controlled randomised clinical trial investigating the effect of neuraminidase inhibitors in adults hospitalised with influenza
by: Bradbury, Naomi, et al.
Published: (2018)

Construction of a Recombinant Plasmid from Newcastle Disease Virus Antigen, Haemagglutinin-Neuraminidase and Lactococcal N-Acetylmuramidase and its Expression
by: Yasid, Nur Adeela
Published: (2009)

Functional ectodomain of the hemagglutinin-neuraminidase protein is expressed in transgenic tobacco cells as a candidate vaccine against Newcastle disease virus.
by: Kok, Song Lai, et al.
Published: (2013)

Expression and purification of hemagglutinin and neuraminidase recombinant protein of avian influenza a virus using immobilised metal affinity chromatography (imac)
by: Chiang, Goh Wei
Published: (2016)

Expression, Purification And Quantitation Of Hemagglutinin-Neuraminidase For Dose-Ranging Assessment Of A Recombinant Protein-Based Newcastle Disease Subunit Vaccine
by: Lye, Ping Ying
Published: (2020)