Increased expression of phosphatidylinositol 3-kinase p110α and gene amplification of PIK3CA in nasopharyngeal carcinoma
Molecular alterations in PIK3CA oncogene that encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K p110α) are commonly found in human cancers. In this study, we examined the expression of PI3K p110α and PIK3CA gene amplification in 74 nasopharyngeal carcinoma (NPC) cases. Immun...
| Main Authors: | Yip, Wai Kien, He, Pei Yuan, Abdullah, Maizaton Atmadini, Yusoff, Suryati, Seow, Heng Fong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2016
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/43361/ http://psasir.upm.edu.my/id/eprint/43361/1/Increased%20expression%20of%20phosphatidylinositol%203-kinase%20p110%CE%B1%20and%20gene%20amplification%20of%20PIK3CA%20in%20nasopharyngeal%20carcinoma.pdf |
Similar Items
Activation of phosphatidylinositol 3-kinase/Akt signaling by EGF downregulates membranous E-cadherin and â-catenin and enhances invasion in nasopharyngeal carcinoma cells.
by: Wai, Kien Yip, et al.
Published: (2012)
by: Wai, Kien Yip, et al.
Published: (2012)
PIK3CA gene mutations in breast carcinoma in Malaysian patients
by: Leong, Vincent Ching Shian, et al.
Published: (2008)
by: Leong, Vincent Ching Shian, et al.
Published: (2008)
Determination of phosphatidylinositol-3-kinase gene copy number and protein expression in nasopharyngeal carcinoma by real-time PCR and immunohistochemistry
by: Firoozinia, Mohammad
Published: (2013)
by: Firoozinia, Mohammad
Published: (2013)
PIK3C Agene mutations in breast carcinoma in Malaysian patients
by: Leong, Vincent Ching-Shian, et al.
Published: (2008)
by: Leong, Vincent Ching-Shian, et al.
Published: (2008)
Increase in tumour-infiltrating lymphocytes with regulatory T cell immunophenotypes and reduced zeta-chain expression in nasopharyngeal carcinoma patients.
by: Seow, Heng Fong, et al.
Published: (2009)
by: Seow, Heng Fong, et al.
Published: (2009)
Role and regulation of phosphatidylinositol 3-kinase ß in platelet integrin α2ß1 signaling
by: Consonni, A., et al.
Published: (2012)
by: Consonni, A., et al.
Published: (2012)
Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala Lumpur, Malaysia
by: Yip, Wai Kien, et al.
Published: (2013)
by: Yip, Wai Kien, et al.
Published: (2013)
Convetional Biopsy To EBV Amplification Kit In Quick Diagnosis Of Nasopharyngeal Carcinoma.
by: Hassan, Shahid
Published: (2004)
by: Hassan, Shahid
Published: (2004)
Diagnosis Of Nasopharyngeal Carcinoma By DNA Amplification Of EBV Genomes In Nasopharyngeal Biopsy And Fine Needle Aspiration Of Neck Nodes.
by: Hassan, Shahid, et al.
Published: (2004)
by: Hassan, Shahid, et al.
Published: (2004)
Rethinking phosphatidylinositol 3-monophosphate
by: Falasca, Marco, et al.
Published: (2009)
by: Falasca, Marco, et al.
Published: (2009)
Evaluation of palbociclib in oral squamous cell carcinoma and the role of PIK3CA in conferring resistance / Nur Syafinaz Zainal
by: Nur Syafinaz, Zainal
Published: (2019)
by: Nur Syafinaz, Zainal
Published: (2019)
Characterisation of tumorspheres generated from nasopharyngeal carcinoma cell line TW06 and chemoresistance to docetaxel
by: Goh, Iris Wen Li, et al.
Published: (2015)
by: Goh, Iris Wen Li, et al.
Published: (2015)
Characterization of tumorspheres generated from nasopharyngeal carcinoma cell line, TW06 and chemoresistance to docetaxel and oxaliplatin
by: Goh, Iris Wen Li, et al.
Published: (2015)
by: Goh, Iris Wen Li, et al.
Published: (2015)
Discovery of highly potent and selective phosphatidylinositol 3-kinase-δ inhibitors for the treatment of blood cancers and autoimmune diseases
by: Buzrieda, Anas
Published: (2021)
by: Buzrieda, Anas
Published: (2021)
Upregulation of Phosphatidylinositol 3-Kinase (PI3K) enhances ethylene biosynthesis and accelerates flower senescence in transgenic nicotiana tabacum L.
by: Dek, Mohd Sabri Pak, et al.
Published: (2017)
by: Dek, Mohd Sabri Pak, et al.
Published: (2017)
Identification Of Novel 14-3-3 Sigma Homodimer Stabiliser In Nasopharyngeal Carcinoma
by: Jabal, Ghazi Ahmad Al
Published: (2023)
by: Jabal, Ghazi Ahmad Al
Published: (2023)
Regulation of phosphatidylinositol 3-kinase (PI3K/Akt) pathway in chicken and duck cells and its implications for influenza A virus pathogenesis
by: Kumar, Sanjeeva
Published: (2018)
by: Kumar, Sanjeeva
Published: (2018)
Diagnosis of nasopharyngeal carcinoma by DNA amplification of
epstein-bar virus genomes in tissue obtained by biopsy and fine-needle aspiration
by: Hassan, Shahid, et al.
Published: (2006)
by: Hassan, Shahid, et al.
Published: (2006)
Overexpression of phospho-Akt correlates with phosphorylation of EGF receptor, FKHR and BAD in nasopharyngeal carcinoma
by: Yip , WK
Published: (2008)
by: Yip , WK
Published: (2008)
Chromosome fragility in nasopharyngeal carcinoma (NPC)
by: Yee, Peter Han Chung
Published: (2007)
by: Yee, Peter Han Chung
Published: (2007)
Elucidation of the WNT & AKT/Phosphoinositide-3-Kinase Pathways in Colorectal Carcinoma
by: Khor, Tin Oo
Published: (2004)
by: Khor, Tin Oo
Published: (2004)
Curcumin modulates nuclear factor kB (NF-KB)-mediated
inflammation in human tenocytes in vitro:
Role of the PHOSPHATIDYLINOSITOL 3-KINASE/Akt PATHWAY
by: Buhrmann, Constanze, et al.
Published: (2011)
by: Buhrmann, Constanze, et al.
Published: (2011)
Activation of phosphatidylinositol 3-kinase ß by the platelet collagen receptors integrin a2ß1 and GPVI: The role of Pyk2 and c-Cbl
by: Manganaro, D., et al.
Published: (2015)
by: Manganaro, D., et al.
Published: (2015)
Epidemiology of Nasopharyngeal Carcinoma (NPC) in Pahang, Malaysia
by: Mohd Yassin, Wardah, et al.
Published: (2016)
by: Mohd Yassin, Wardah, et al.
Published: (2016)
Genetic susceptibility factors in familial nasopharyngeal carcinoma
by: Kaderi, Mohd Arifin, et al.
Published: (2016)
by: Kaderi, Mohd Arifin, et al.
Published: (2016)
Nasopharyngeal carcinoma (NPC) with liver metastasis in pregnancy
by: Zakaria, Atiqah Farah, et al.
Published: (2016)
by: Zakaria, Atiqah Farah, et al.
Published: (2016)
Study of Sensor Protein Expresssion in Nasopharyngeal Carcinoma
by: Kaliswaran, Pannirselvam
Published: (2017)
by: Kaliswaran, Pannirselvam
Published: (2017)
Trainable model for segmenting and identifying Nasopharyngeal carcinoma
by: Mohammed, Mazin Abed, et al.
Published: (2018)
by: Mohammed, Mazin Abed, et al.
Published: (2018)
Risk factors for malnutrition in patients with nasopharyngeal carcinoma
by: Wang, Pengpeng, et al.
Published: (2023)
by: Wang, Pengpeng, et al.
Published: (2023)
Preliminary findings of down-regulated genes in nasopharyngeal carcinoma
by: Sim, Edmund U. H., et al.
Published: (2008)
by: Sim, Edmund U. H., et al.
Published: (2008)
Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma
by: Sim, Edmund, et al.
Published: (2012)
by: Sim, Edmund, et al.
Published: (2012)
Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
by: Chua, Suk Ngo
Published: (2011)
by: Chua, Suk Ngo
Published: (2011)
mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate
by: Marat, A., et al.
Published: (2017)
by: Marat, A., et al.
Published: (2017)
Small cell neuroendocrine carcinoma: a rare second primary malignancy after treatment of nasopharyngeal carcinoma
by: Madhusudhan, Krishnamoorthy, et al.
Published: (2018)
by: Madhusudhan, Krishnamoorthy, et al.
Published: (2018)
p53-Mdm2 interaction targeted therapy by Nutlin-3 on nasopharyngeal carcinoma cells / Voon Yee Lin
by: Voon, Yee Lin
Published: (2016)
by: Voon, Yee Lin
Published: (2016)
Potentiation Of The Nasopharyngeal Carcinoma Cell Lines By Maritoclax To Abt-263 In 2-Dimensional And 3-Dimensional Cell Culture Methods
by: Lian, Benedict Shi Xiang
Published: (2017)
by: Lian, Benedict Shi Xiang
Published: (2017)
Non-invasive tests for the detection of nasopharyngeal carcinoma / Sivanesan Vijaya Mohan
by: Sivanesan Vijaya , Mohan
Published: (2020)
by: Sivanesan Vijaya , Mohan
Published: (2020)
Trismus as a rare presenting symptom in a pediatric nasopharyngeal carcinoma
by: Maithrea, N., et al.
Published: (2017)
by: Maithrea, N., et al.
Published: (2017)
Recurrent nasopharyngeal carcinoma with a rare presentation of anterior chest wall swelling
by: Rosla, Luqman, et al.
Published: (2017)
by: Rosla, Luqman, et al.
Published: (2017)
The expression of microrna-744 (MIR-744) in nasopharyngeal carcinoma: a preliminary study
by: Othman, Noor Syarmila, et al.
Published: (2018)
by: Othman, Noor Syarmila, et al.
Published: (2018)
Similar Items
-
Activation of phosphatidylinositol 3-kinase/Akt signaling by EGF downregulates membranous E-cadherin and â-catenin and enhances invasion in nasopharyngeal carcinoma cells.
by: Wai, Kien Yip, et al.
Published: (2012) -
PIK3CA gene mutations in breast carcinoma in Malaysian patients
by: Leong, Vincent Ching Shian, et al.
Published: (2008) -
Determination of phosphatidylinositol-3-kinase gene copy number and protein expression in nasopharyngeal carcinoma by real-time PCR and immunohistochemistry
by: Firoozinia, Mohammad
Published: (2013) -
PIK3C Agene mutations in breast carcinoma in Malaysian patients
by: Leong, Vincent Ching-Shian, et al.
Published: (2008) -
Increase in tumour-infiltrating lymphocytes with regulatory T cell immunophenotypes and reduced zeta-chain expression in nasopharyngeal carcinoma patients.
by: Seow, Heng Fong, et al.
Published: (2009)