β-mangostin suppresses LA-7 cells proliferation in vitro and in vivo: involvement of antioxidant enzyme modulation; suppression of matrix metalloproteinase and α6β4 integrin signalling pathways

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β-mangostin suppresses LA-7 cells proliferation in vitro and in vivo: involvement of antioxidant enzyme modulation; suppression of matrix metalloproteinase and α6β4 integrin signalling pathways

β-mangostin (βM) was isolated from Cratoxylum arborescens to investigate anti-breast cancer effect in vitro and in vivo. βM exhibited an inhibitory effect on the growth of LA-7 cells in vitro with apoptosis formation. In the animal model, βM treatment was found to be effective in improving the tissu...

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Bibliographic Details
Main Authors:	Mohan, Suvitha Syam, Abdul, Ahmad Bustamam, Mohd Hashim, Najihah, Ghaderian, Mostafa, Hobani, Yahya Hasan, Makeen, Anwar, Abdelwahab, Siddig Ibrahim, Mohan, Syam
Format:	Article
Language:	English
Published:	Elsevier 2016
Online Access:	http://psasir.upm.edu.my/id/eprint/43343/ http://psasir.upm.edu.my/id/eprint/43343/1/43343.pdf

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