Comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters

In this study, we compared the effect of formulation parameters on the physicochemical properties of lutein nanodispersions prepared using a low- and high-energy approach, i.e., solvent displacement (SD) and high-pressure valve homogenization (HPH), respectively. The lutein concentration had a signi...

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Main Authors: Tan, Tai Boon, Yussof, Nor Shariffa, Abas, Faridah, Mirhosseini, Seyed Hamed, Nehdi, Imededdine Arbi, Tan, Chin Ping
Format: Article
Language:English
Published: Elsevier 2016
Online Access:http://psasir.upm.edu.my/id/eprint/43279/
http://psasir.upm.edu.my/id/eprint/43279/1/Comparing%20the%20formation%20of%20lutein%20nanodispersion%20prepared%20by%20using%20solvent%20displacement%20method%20and%20high-pressure%20valve%20homogenization%20effects%20of%20formulation%20parameters.pdf
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author Tan, Tai Boon
Yussof, Nor Shariffa
Abas, Faridah
Mirhosseini, Seyed Hamed
Nehdi, Imededdine Arbi
Tan, Chin Ping
author_facet Tan, Tai Boon
Yussof, Nor Shariffa
Abas, Faridah
Mirhosseini, Seyed Hamed
Nehdi, Imededdine Arbi
Tan, Chin Ping
author_sort Tan, Tai Boon
building UPM Institutional Repository
collection Online Access
description In this study, we compared the effect of formulation parameters on the physicochemical properties of lutein nanodispersions prepared using a low- and high-energy approach, i.e., solvent displacement (SD) and high-pressure valve homogenization (HPH), respectively. The lutein concentration had a significant effect on the particle size (PS) and particle size distribution (PSD) of nanodispersions that were prepared by using both methods. However, Tween 80 concentration and organic-phase-to-aqueous-phase volume ratio (OAR) only had a significant effect on the PS of nanodispersions prepared by SD. Under all the variations in the formulation parameters, the PSs and PSDs of nanodispersions prepared by SD and HPH were not significantly different. At 0.1% lutein concentration, 0.1% Tween 80 concentration and OAR of 1:9, the nanodispersions prepared by using both methods displayed minimum PS and excellent lutein retentions (>90%). This study showed that SD is a suitable alternative to HPH for preparing lutein nanodispersions.
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institution Universiti Putra Malaysia
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language English
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publisher Elsevier
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spelling upm-432792017-04-17T02:39:23Z http://psasir.upm.edu.my/id/eprint/43279/ Comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters Tan, Tai Boon Yussof, Nor Shariffa Abas, Faridah Mirhosseini, Seyed Hamed Nehdi, Imededdine Arbi Tan, Chin Ping In this study, we compared the effect of formulation parameters on the physicochemical properties of lutein nanodispersions prepared using a low- and high-energy approach, i.e., solvent displacement (SD) and high-pressure valve homogenization (HPH), respectively. The lutein concentration had a significant effect on the particle size (PS) and particle size distribution (PSD) of nanodispersions that were prepared by using both methods. However, Tween 80 concentration and organic-phase-to-aqueous-phase volume ratio (OAR) only had a significant effect on the PS of nanodispersions prepared by SD. Under all the variations in the formulation parameters, the PSs and PSDs of nanodispersions prepared by SD and HPH were not significantly different. At 0.1% lutein concentration, 0.1% Tween 80 concentration and OAR of 1:9, the nanodispersions prepared by using both methods displayed minimum PS and excellent lutein retentions (>90%). This study showed that SD is a suitable alternative to HPH for preparing lutein nanodispersions. Elsevier 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/43279/1/Comparing%20the%20formation%20of%20lutein%20nanodispersion%20prepared%20by%20using%20solvent%20displacement%20method%20and%20high-pressure%20valve%20homogenization%20effects%20of%20formulation%20parameters.pdf Tan, Tai Boon and Yussof, Nor Shariffa and Abas, Faridah and Mirhosseini, Seyed Hamed and Nehdi, Imededdine Arbi and Tan, Chin Ping (2016) Comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters. Journal of Food Engineering, 177. pp. 65-71. ISSN 0260-8774; ESSN: 1873-5770 http://www.sciencedirect.com/science/article/pii/S026087741530090X 10.1016/j.jfoodeng.2015.12.020
spellingShingle Tan, Tai Boon
Yussof, Nor Shariffa
Abas, Faridah
Mirhosseini, Seyed Hamed
Nehdi, Imededdine Arbi
Tan, Chin Ping
Comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters
title Comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters
title_full Comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters
title_fullStr Comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters
title_full_unstemmed Comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters
title_short Comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters
title_sort comparing the formation of lutein nanodispersion prepared by using solvent displacement method and high-pressure valve homogenization: effects of formulation parameters
url http://psasir.upm.edu.my/id/eprint/43279/
http://psasir.upm.edu.my/id/eprint/43279/
http://psasir.upm.edu.my/id/eprint/43279/
http://psasir.upm.edu.my/id/eprint/43279/1/Comparing%20the%20formation%20of%20lutein%20nanodispersion%20prepared%20by%20using%20solvent%20displacement%20method%20and%20high-pressure%20valve%20homogenization%20effects%20of%20formulation%20parameters.pdf