Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways

QR Code

Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways

Background: Dillenia suffruticosa root dichloromethane extract (DCM-DS) has been reported to exhibit strong cytotoxicity towards breast cancer cells. The present study was designed to investigate the cell cycle profile, mode of cell death and signalling pathways of DCM-DS-treated human caspase-3 def...

Full description

Bibliographic Details
Main Authors:	Foo, Jhi Biau, Saiful Yazan, Latifah, Tor, Yin Sim, Armania, Nurdin, Ismail, Norsharina, Imam, Mustapha Umar, Yeap, Swee Keong, Cheah, Yoke Kqueen, Abdullah, Rasedee, Ismail, Maznah
Format:	Article
Language:	English
Published:	BioMed Central 2014
Online Access:	http://psasir.upm.edu.my/id/eprint/41932/ http://psasir.upm.edu.my/id/eprint/41932/1/41932.pdf

Similar Items

Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)

Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa
by: Tor, Yin Sim, et al.
Published: (2014)

Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis
by: Armania, Nurdin, et al.
Published: (2013)

Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl acetate extract of Dillenia suffruticosa and its chemical profile
by: Tor, Yin Sim, et al.
Published: (2015)

Dillenia suffruticosa exhibited antioxidant and cytotoxic activity through induction of apoptosis and G2/M cell cycle arrest
by: Armania, Nurdin, et al.
Published: (2013)

Induction of apoptosis and the signalling pathways involved by dillenia suffruticosa dichloromethane root extract in mcf-7 and mda-mb-231 breast cancer cells
by: Foo, Jhi Biau
Published: (2015)

Bioassay-guided isolation of Triterpene compounds from Dillenia suffruticosa and their cytotoxic activities against cancer cells
by: Nurdin, Armania, et al.
Published: (2021)

Dillenia suffruticosa dichloromethane root extract induced apoptosis towards MDA-MB-231 triple negative breast cancer cells
by: Foo, J. B., et al.
Published: (2016)

Bioassay-guided isolation of triterpene compounds from Dillenia suffruticosa and their cytotoxic activities against cancer cells
by: Armania Nurdin,, et al.
Published: (2022)

Extracts of Dillenia suffruticosa for medical treatments
by: Saiful Yazan, Latifah, et al.
Published: (2012)

Apoptotic-related signalling pathways in mcf-7 cells treated with ethyl acetate extract of dillenia suffruticosa, and isolation of its major compounds
by: Yin, Sim Tor
Published: (2015)

Anti breast cancer properties and toxicity of Dillenia suffruticosa root aqueous extract in BALB/c mice
by: Saiful Yazan, Latifah, et al.
Published: (2015)

Estimation of the aboveground biomass in a Dillenia suffruticosa stand, Malaysia
by: Kueh, Roland Jui Heng, et al.
Published: (2014)

Dillenia species: a review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies
by: Saiful Yazan, Latifah, et al.
Published: (2014)

Phytochemical screening, antioxidant and antibacterial activities of extracts and fractions of Dillenia suffruticosa leaves
by: Farazimah Yakop,, et al.
Published: (2020)

Induction of cell cycle arrest and apoptosis by copper complex Cu(SBCM)₂ towards oestrogen-receptor positive MCF-7 breast cancer cells
by: Jhi, Biau Foo, et al.
Published: (2019)

Antibacterial activity of Dillenia suffruticosa leaf extract against Xanthomonas oryzae pv. oryzae
by: Sani, Mohd Fardzryn
Published: (2016)

Dillenia suffruticosa dichloromethane root extract reduced metastasis of 4T1 cells to the liver and heart without causing toxicity in female BALB/c mice
by: Saiful Yazan, Latifah, et al.
Published: (2019)

Kenaf seed oil from supercritical carbon dioxide fluid extraction induced G1 phase cell cycle arrest and apoptosis in leukemia cells
by: Foo, Jhi Biau, et al.
Published: (2011)

Apoptosis and cell cycle arrest of human colorectal cancer cell line HT-29 induced by vanillin.
by: Ho, Ket Li, et al.
Published: (2009)

Bcl-2 was downregulated in G2/M-arrest breast cancer cells MCF-7-treated with nordamnacanthal
by: Saiful Yazan, Latifah, et al.
Published: (2010)

Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)

Kandungan logam berat dalam persekitaran tanih dan dillenia suffruticosa di Kawasan Lombong Pelepah Kanan, Kota Tinggi Johor
by: Sahibin Abd. Rahim,, et al.
Published: (2011)

Effects of triterpenoids from Luvunga scandens on cytotoxic, cell cycle arrest and gene expressions in MCF-7 cells
by: Bakhtiar, M. Taher, et al.
Published: (2016)

Nordamnacanthal induced apoptosis and mitotic-G2/M arrest with downregulation of Bcl-2 in the human breast cancer cell line (MCF-7).
by: Ishak , Norsyafini, et al.
Published: (2010)

Induction of apoptosis and G2/M arrest by ampelopsin E from Dryobalanops towards triple negative breast cancer cells, MDA-MB-231
by: Abd Rahman, Napsiah, et al.
Published: (2016)

Neuroprotective effects of germinated brown rice against hydrogen peroxide induced cell death in human SH-SY5Y cells
by: Ismail, Norsharina, et al.
Published: (2012)

Eco-friendly formulated zinc oxide nanoparticles: induction of cell cycle arrest and apoptosis in the MCF-7 cancer cell line
by: Moghaddam, Amin Boroumand, et al.
Published: (2017)

Apoptosis and cell cycle arrest of MCF-7R breast carcinoma cells by bis(phosphane)copper(I) thiocarbamides derivative compounds
by: Ooi, Kah Kooi
Published: (2017)

Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: Its activation coupled with G0/G1 phase cell cycle arrest.
by: Mohan, Syam, et al.
Published: (2010)

Flavokawain Derivative FLS Induced G2/M Arrest and Apoptosis on Breast Cancer MCF-7 Cell Line
by: Norlaily, Mohd Ali, et al.
Published: (2016)

Artonin E induces p53-independent g1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cell
by: Etti, Imaobong Christopher, et al.
Published: (2017)

Cardamonin induces apoptosis in human nasopharyngeal carcinoma cells via mitochondrial death pathway mediated by caspase-3 and caspase-8 activation, independent of caspase-9 signalling responses
by: Chiang, Michelle
Published: (2016)

β-Mangostin induces p53-dependent G2/M cell cycle arrest and apoptosis through ROS mediated mitochondrial pathway and NfkB suppression in MCF-7 cells
by: Syam, Suvitha, et al.
Published: (2014)

Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival
by: Xuan, Pu, et al.
Published: (2016)

Human bone marrow-derived Mesenchymal stem cells suppress T cell proliferation by inducing cell cycle arrest
by: Tong, Chih Kong, et al.
Published: (2008)

Arborinine from Glycosmis Pentaphylla (retz.) DC induces apoptosis through activation of Caspase-3/7 in human mammary gland Adenocarcinoma (MCF-7) cell line
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)

Mechanistic basis for protection of differentiated SH-SY5Y cells by oryzanol-rich fraction against hydrogen peroxide-induced neurotoxicity
by: Ismail, Norsharina, et al.
Published: (2014)

Rice bran phytic acid (IP6) induces growth inhibition, cell cycle arrest and apoptosis on human colorectal adenocarcinoma cells
by: Mohd Esa, Norhaizan, et al.
Published: (2010)

Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)