Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus
Newcastle disease (ND) is a major disease in poultry industry that caused high loss and mortality. Fundamental study on the virus-host interactions is needed to address the issue of repeated outbreaks of NDV in Asia. In this study, the effect of inflammatory stress on the viability toward the develo...
| Main Authors: | , , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
Faculty of Veterinary Medicine, Universiti Putra Malaysia
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/41412/ http://psasir.upm.edu.my/id/eprint/41412/1/41412.pdf |
| _version_ | 1848849688372969472 |
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| author | Teo, Kristeen Ye Wen Omar, Abdul Rahman Yeap, Swee Keong Tan, Sheau Wei Tan, Soon Guan Mohammed Alitheen, Noorjahan Banu |
| author_facet | Teo, Kristeen Ye Wen Omar, Abdul Rahman Yeap, Swee Keong Tan, Sheau Wei Tan, Soon Guan Mohammed Alitheen, Noorjahan Banu |
| author_sort | Teo, Kristeen Ye Wen |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Newcastle disease (ND) is a major disease in poultry industry that caused high loss and mortality. Fundamental study on the virus-host interactions is needed to address the issue of repeated outbreaks of NDV in Asia. In this study, the effect of inflammatory stress on the viability toward the development of humoral immunity was investigated in chicken IgM+ B lymphocytes when infected with different genotypes of velogenic NDV. When infected with NDV genotype VII UPM/IBS/002/2011 and genotype VIII AF2240, reduction of IgM+ B lymphocytes population and infiltration of macrophage was observed in the chicken bursa of Fabricius. The increment of macrophage population subsequently resulted in the elevation of nitric oxide (NO) content in the infected chickens with AF2240 causing higher increment of NO compared to UPM/IBS/002/2011. In brief, both genotypes of NDV strains caused different immune response in chicken enriched B lymphocytes upon virus infection. |
| first_indexed | 2025-11-15T09:54:22Z |
| format | Conference or Workshop Item |
| id | upm-41412 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:54:22Z |
| publishDate | 2013 |
| publisher | Faculty of Veterinary Medicine, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-414122018-08-15T01:20:52Z http://psasir.upm.edu.my/id/eprint/41412/ Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus Teo, Kristeen Ye Wen Omar, Abdul Rahman Yeap, Swee Keong Tan, Sheau Wei Tan, Soon Guan Mohammed Alitheen, Noorjahan Banu Newcastle disease (ND) is a major disease in poultry industry that caused high loss and mortality. Fundamental study on the virus-host interactions is needed to address the issue of repeated outbreaks of NDV in Asia. In this study, the effect of inflammatory stress on the viability toward the development of humoral immunity was investigated in chicken IgM+ B lymphocytes when infected with different genotypes of velogenic NDV. When infected with NDV genotype VII UPM/IBS/002/2011 and genotype VIII AF2240, reduction of IgM+ B lymphocytes population and infiltration of macrophage was observed in the chicken bursa of Fabricius. The increment of macrophage population subsequently resulted in the elevation of nitric oxide (NO) content in the infected chickens with AF2240 causing higher increment of NO compared to UPM/IBS/002/2011. In brief, both genotypes of NDV strains caused different immune response in chicken enriched B lymphocytes upon virus infection. Faculty of Veterinary Medicine, Universiti Putra Malaysia 2013 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/41412/1/41412.pdf Teo, Kristeen Ye Wen and Omar, Abdul Rahman and Yeap, Swee Keong and Tan, Sheau Wei and Tan, Soon Guan and Mohammed Alitheen, Noorjahan Banu (2013) Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus. In: World’s Poultry Science Association (Malaysia Branch) and World Veterinary Poultry Association (Malaysia Branch) Scientific Conference 2013, 30 Nov.-1 Dec. 2013, Faculty of Veterinary Medicine, Universiti Putra Malaysia. (pp. 120-122). http://www.vet.upm.edu.my/dokumen/90301_proceeding_WPSA_V2_first_second_XX_new_20121013_%281%29.pdf |
| spellingShingle | Teo, Kristeen Ye Wen Omar, Abdul Rahman Yeap, Swee Keong Tan, Sheau Wei Tan, Soon Guan Mohammed Alitheen, Noorjahan Banu Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus |
| title | Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus |
| title_full | Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus |
| title_fullStr | Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus |
| title_full_unstemmed | Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus |
| title_short | Responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic Newcastle disease virus |
| title_sort | responses of enriched chicken b lymphocytes population towards infection of different genotypes of velogenic newcastle disease virus |
| url | http://psasir.upm.edu.my/id/eprint/41412/ http://psasir.upm.edu.my/id/eprint/41412/ http://psasir.upm.edu.my/id/eprint/41412/1/41412.pdf |