Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs
Twenty-four mongrel dogs were subjected to sanguineous and crystalloid cardioplegia for a period of thirty minutes at 20°C and 25°C systemic hypothermia during cardiopulmonary bypass. Cardioplegic solutions were administered at 4°C to induce cardioplegia. Physiological functions of the myocardium re...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Veterinary Association Malaysia
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/41113/ http://psasir.upm.edu.my/id/eprint/41113/1/Evaluation%20of%20sanguineous%20and%20crystalloid%20cardioplegic%20solutions%20during%20total.pdf |
| _version_ | 1848849607693434880 |
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| author | George, R. S. Jayaprakash, R. Ramanujam, K. Radhakrishnan , C. Archibald, D. |
| author_facet | George, R. S. Jayaprakash, R. Ramanujam, K. Radhakrishnan , C. Archibald, D. |
| author_sort | George, R. S. |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Twenty-four mongrel dogs were subjected to sanguineous and crystalloid cardioplegia for a period of thirty minutes at 20°C and 25°C systemic hypothermia during cardiopulmonary bypass. Cardioplegic solutions were administered at 4°C to induce cardioplegia. Physiological functions of the myocardium revealed that the cardiac function returned to normal sinus rhythm without any loss when blood cardioplegic solution was used at both hypothermic temperatures. The time taken for cardioplegia and cardiac electrical quiescence was achieved earlier at 20°C. Animals in sanguineous cardioplegic group revealed better functional return and revival of cardiac musculature in terms of lesser applications of defibrillator, lesser requirement of inotropic support and early cardiac contraction. This study revealed that sanguineous cardioplegic solution at a systemic temperature of 20°C was found to afford better myocardial protection during an arrest period of 30 minutes. |
| first_indexed | 2025-11-15T09:53:05Z |
| format | Article |
| id | upm-41113 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:53:05Z |
| publishDate | 2009 |
| publisher | Veterinary Association Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-411132015-12-02T07:42:56Z http://psasir.upm.edu.my/id/eprint/41113/ Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs George, R. S. Jayaprakash, R. Ramanujam, K. Radhakrishnan , C. Archibald, D. Twenty-four mongrel dogs were subjected to sanguineous and crystalloid cardioplegia for a period of thirty minutes at 20°C and 25°C systemic hypothermia during cardiopulmonary bypass. Cardioplegic solutions were administered at 4°C to induce cardioplegia. Physiological functions of the myocardium revealed that the cardiac function returned to normal sinus rhythm without any loss when blood cardioplegic solution was used at both hypothermic temperatures. The time taken for cardioplegia and cardiac electrical quiescence was achieved earlier at 20°C. Animals in sanguineous cardioplegic group revealed better functional return and revival of cardiac musculature in terms of lesser applications of defibrillator, lesser requirement of inotropic support and early cardiac contraction. This study revealed that sanguineous cardioplegic solution at a systemic temperature of 20°C was found to afford better myocardial protection during an arrest period of 30 minutes. Veterinary Association Malaysia 2009 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/41113/1/Evaluation%20of%20sanguineous%20and%20crystalloid%20cardioplegic%20solutions%20during%20total.pdf George, R. S. and Jayaprakash, R. and Ramanujam, K. and Radhakrishnan , C. and Archibald, D. (2009) Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs. Jurnal Veterinar Malaysia, 21 (1). pp. 15-21. ISSN 9128-2506 |
| spellingShingle | George, R. S. Jayaprakash, R. Ramanujam, K. Radhakrishnan , C. Archibald, D. Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs |
| title | Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs |
| title_full | Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs |
| title_fullStr | Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs |
| title_full_unstemmed | Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs |
| title_short | Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs |
| title_sort | evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs |
| url | http://psasir.upm.edu.my/id/eprint/41113/ http://psasir.upm.edu.my/id/eprint/41113/1/Evaluation%20of%20sanguineous%20and%20crystalloid%20cardioplegic%20solutions%20during%20total.pdf |