In vitro antiplasmodial properties of selected plants of Sabah
The antiplasmodial activity of the crude extracts of thirty plant species collected from Sabah was evaluated using chloroquine-sensitive strain (D10) and chloroquine-resistant strain (Gombak A) of Plasmodium falciparum. Significant activities were observed for the bark extract of Polyalthia insignis...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Universiti Putra Malaysia Press
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/40635/ http://psasir.upm.edu.my/id/eprint/40635/1/97.%20In%20vitro%20antiplasmodial%20properties%20of%20selected%20plants%20of%20Sabah.pdf |
| _version_ | 1848849482603560960 |
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| author | Shaari, Khozirah Abdullah, Noor Rain Mohd Janib, Siti Najila Imiyabir, Zamrie Madani, L. Chomel, Rohaya Mohamad, Rosilawati Hashim, Nuziah Goh, S. H. Ismail, Zakiah |
| author_facet | Shaari, Khozirah Abdullah, Noor Rain Mohd Janib, Siti Najila Imiyabir, Zamrie Madani, L. Chomel, Rohaya Mohamad, Rosilawati Hashim, Nuziah Goh, S. H. Ismail, Zakiah |
| author_sort | Shaari, Khozirah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The antiplasmodial activity of the crude extracts of thirty plant species collected from Sabah was evaluated using chloroquine-sensitive strain (D10) and chloroquine-resistant strain (Gombak A) of Plasmodium falciparum. Significant activities were observed for the bark extract of Polyalthia insignis (IC50 3.89 and 11.89 µg/ml against Gombak A and D10, respectively), the leaf extracts of Kopsia dasyrachis (4.62 µg/ml against Gombak A) and Litsea elliptibacea (IC50 8.88 µg/ml against Gombak A), as well as the leaf and bark extracts of Neouvaria acuminatissima (IC50 6.90-10.08 and 0.69 µg/ml against Gombak A and D10, respectively), and the bark extract of Polyalthia microtus (IC50 9.0 and 12.12 µg/ml against Gombak A and D10, respectively). |
| first_indexed | 2025-11-15T09:51:06Z |
| format | Article |
| id | upm-40635 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T09:51:06Z |
| publishDate | 2011 |
| publisher | Universiti Putra Malaysia Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-406352016-01-05T08:28:41Z http://psasir.upm.edu.my/id/eprint/40635/ In vitro antiplasmodial properties of selected plants of Sabah Shaari, Khozirah Abdullah, Noor Rain Mohd Janib, Siti Najila Imiyabir, Zamrie Madani, L. Chomel, Rohaya Mohamad, Rosilawati Hashim, Nuziah Goh, S. H. Ismail, Zakiah The antiplasmodial activity of the crude extracts of thirty plant species collected from Sabah was evaluated using chloroquine-sensitive strain (D10) and chloroquine-resistant strain (Gombak A) of Plasmodium falciparum. Significant activities were observed for the bark extract of Polyalthia insignis (IC50 3.89 and 11.89 µg/ml against Gombak A and D10, respectively), the leaf extracts of Kopsia dasyrachis (4.62 µg/ml against Gombak A) and Litsea elliptibacea (IC50 8.88 µg/ml against Gombak A), as well as the leaf and bark extracts of Neouvaria acuminatissima (IC50 6.90-10.08 and 0.69 µg/ml against Gombak A and D10, respectively), and the bark extract of Polyalthia microtus (IC50 9.0 and 12.12 µg/ml against Gombak A and D10, respectively). Universiti Putra Malaysia Press 2011-01 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/40635/1/97.%20In%20vitro%20antiplasmodial%20properties%20of%20selected%20plants%20of%20Sabah.pdf Shaari, Khozirah and Abdullah, Noor Rain and Mohd Janib, Siti Najila and Imiyabir, Zamrie and Madani, L. and Chomel, Rohaya and Mohamad, Rosilawati and Hashim, Nuziah and Goh, S. H. and Ismail, Zakiah (2011) In vitro antiplasmodial properties of selected plants of Sabah. Pertanika Journal of Science & Technology, 19 (1). pp. 11-17. ISSN 0128-7680; ESSN: 2231-8526 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2019%20%281%29%20Jan.%202011/%236%20Pg%2011-17.pdf |
| spellingShingle | Shaari, Khozirah Abdullah, Noor Rain Mohd Janib, Siti Najila Imiyabir, Zamrie Madani, L. Chomel, Rohaya Mohamad, Rosilawati Hashim, Nuziah Goh, S. H. Ismail, Zakiah In vitro antiplasmodial properties of selected plants of Sabah |
| title | In vitro antiplasmodial properties of selected plants of Sabah |
| title_full | In vitro antiplasmodial properties of selected plants of Sabah |
| title_fullStr | In vitro antiplasmodial properties of selected plants of Sabah |
| title_full_unstemmed | In vitro antiplasmodial properties of selected plants of Sabah |
| title_short | In vitro antiplasmodial properties of selected plants of Sabah |
| title_sort | in vitro antiplasmodial properties of selected plants of sabah |
| url | http://psasir.upm.edu.my/id/eprint/40635/ http://psasir.upm.edu.my/id/eprint/40635/ http://psasir.upm.edu.my/id/eprint/40635/1/97.%20In%20vitro%20antiplasmodial%20properties%20of%20selected%20plants%20of%20Sabah.pdf |