Chemical constituents from Garcinia maingayi and Garcinia parvifolia (Guttiferae) and their biological activities
Detail chemical studies on Garcinia maingayi have yielded one xanthone, 1,3,7-trihydroxy- 2-(3-methylbut-2-enyl)-xanthone, one benzophenone, isoxanthochymol, one benzoic acid derivative 3,4-dihydroxy-methylbenzoate and two triterpenoids, stigmasterol and sitosterol. Meanwhile, investigations on Garc...
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| Format: | Article |
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Universiti Putra Malaysia Press
2007
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| Online Access: | http://psasir.upm.edu.my/id/eprint/40532/ |
| _version_ | 1848849454194491392 |
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| author | Ee, Gwendoline Cheng Lian Cheow, Yuen Lin |
| author_facet | Ee, Gwendoline Cheng Lian Cheow, Yuen Lin |
| author_sort | Ee, Gwendoline Cheng Lian |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Detail chemical studies on Garcinia maingayi have yielded one xanthone, 1,3,7-trihydroxy- 2-(3-methylbut-2-enyl)-xanthone, one benzophenone, isoxanthochymol, one benzoic acid derivative 3,4-dihydroxy-methylbenzoate and two triterpenoids, stigmasterol and sitosterol. Meanwhile, investigations on Garcinia parvifolia have afforded one triterpenoid, ?-amyrin and two xanthones, cowanin and rubraxanthone. Their structures were derived based on spectroscopic evidence, mainly ID and 2D NMR spectroscopy. Acetylation reaction was carried out on rubraxanthone to yield triacetate rubraxanthone. It was found that the pure rubraxanthone was strongly active against the larvae of Aedes aegypti with LC50 value of 15.49 μg/ ml and HL-60 cells line with an IC50 value of 7.5 μg/ ml. |
| first_indexed | 2025-11-15T09:50:39Z |
| format | Article |
| id | upm-40532 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T09:50:39Z |
| publishDate | 2007 |
| publisher | Universiti Putra Malaysia Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-405322015-11-20T01:38:37Z http://psasir.upm.edu.my/id/eprint/40532/ Chemical constituents from Garcinia maingayi and Garcinia parvifolia (Guttiferae) and their biological activities Ee, Gwendoline Cheng Lian Cheow, Yuen Lin Detail chemical studies on Garcinia maingayi have yielded one xanthone, 1,3,7-trihydroxy- 2-(3-methylbut-2-enyl)-xanthone, one benzophenone, isoxanthochymol, one benzoic acid derivative 3,4-dihydroxy-methylbenzoate and two triterpenoids, stigmasterol and sitosterol. Meanwhile, investigations on Garcinia parvifolia have afforded one triterpenoid, ?-amyrin and two xanthones, cowanin and rubraxanthone. Their structures were derived based on spectroscopic evidence, mainly ID and 2D NMR spectroscopy. Acetylation reaction was carried out on rubraxanthone to yield triacetate rubraxanthone. It was found that the pure rubraxanthone was strongly active against the larvae of Aedes aegypti with LC50 value of 15.49 μg/ ml and HL-60 cells line with an IC50 value of 7.5 μg/ ml. Universiti Putra Malaysia Press 2007-07 Article PeerReviewed Ee, Gwendoline Cheng Lian and Cheow, Yuen Lin (2007) Chemical constituents from Garcinia maingayi and Garcinia parvifolia (Guttiferae) and their biological activities. Pertanika Journal of Science & Technology, 15 (2). pp. 95-102. ISSN 0128-7680; ESSN: 2231-8526 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2015%20%282%29%20Jul.%202007/05%20PAGE%2095-102.pdf |
| spellingShingle | Ee, Gwendoline Cheng Lian Cheow, Yuen Lin Chemical constituents from Garcinia maingayi and Garcinia parvifolia (Guttiferae) and their biological activities |
| title | Chemical constituents from Garcinia maingayi and Garcinia parvifolia (Guttiferae) and their biological activities |
| title_full | Chemical constituents from Garcinia maingayi and Garcinia parvifolia (Guttiferae) and their biological activities |
| title_fullStr | Chemical constituents from Garcinia maingayi and Garcinia parvifolia (Guttiferae) and their biological activities |
| title_full_unstemmed | Chemical constituents from Garcinia maingayi and Garcinia parvifolia (Guttiferae) and their biological activities |
| title_short | Chemical constituents from Garcinia maingayi and Garcinia parvifolia (Guttiferae) and their biological activities |
| title_sort | chemical constituents from garcinia maingayi and garcinia parvifolia (guttiferae) and their biological activities |
| url | http://psasir.upm.edu.my/id/eprint/40532/ http://psasir.upm.edu.my/id/eprint/40532/ |