A review on the effects of probiotics and antibiotics towards Clostridium difficile infections

Clostridium difficile can cause severe diseases with significant morbidity and mortality in infected patients. The rate of Clostridium difficile infection is high in North America and European countries. Metronidazole and vancomycin have been recommended as the treatments of choice since 1990s. Recu...

Full description

Bibliographic Details
Main Authors: Azman, Hazirah, Loong, Yik Yee, Abdul Aziz, Rushdan, Awang Hamat, Rukman, Abd Manap, Mohd Yazid
Format: Article
Language:English
Published: Universiti Putra Malaysia Press 2013
Online Access:http://psasir.upm.edu.my/id/eprint/40520/
http://psasir.upm.edu.my/id/eprint/40520/1/35.%20A%20Review%20on%20the%20Effects%20of%20Probiotics%20and%20Antibiotics%20towards.pdf
_version_ 1848849450658693120
author Azman, Hazirah
Loong, Yik Yee
Abdul Aziz, Rushdan
Awang Hamat, Rukman
Abd Manap, Mohd Yazid
author_facet Azman, Hazirah
Loong, Yik Yee
Abdul Aziz, Rushdan
Awang Hamat, Rukman
Abd Manap, Mohd Yazid
author_sort Azman, Hazirah
building UPM Institutional Repository
collection Online Access
description Clostridium difficile can cause severe diseases with significant morbidity and mortality in infected patients. The rate of Clostridium difficile infection is high in North America and European countries. Metronidazole and vancomycin have been recommended as the treatments of choice since 1990s. Recurrent infection due to Clostridium difficile is common after several days of antibiotic administration. Probiotics have been used in these patients as an adjunct treatment with some successful findings. However, a detailed investigation on the use of probiotic for infected patients is still needed, particularly for its real efficacy.
first_indexed 2025-11-15T09:50:35Z
format Article
id upm-40520
institution Universiti Putra Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T09:50:35Z
publishDate 2013
publisher Universiti Putra Malaysia Press
recordtype eprints
repository_type Digital Repository
spelling upm-405202016-05-25T07:27:54Z http://psasir.upm.edu.my/id/eprint/40520/ A review on the effects of probiotics and antibiotics towards Clostridium difficile infections Azman, Hazirah Loong, Yik Yee Abdul Aziz, Rushdan Awang Hamat, Rukman Abd Manap, Mohd Yazid Clostridium difficile can cause severe diseases with significant morbidity and mortality in infected patients. The rate of Clostridium difficile infection is high in North America and European countries. Metronidazole and vancomycin have been recommended as the treatments of choice since 1990s. Recurrent infection due to Clostridium difficile is common after several days of antibiotic administration. Probiotics have been used in these patients as an adjunct treatment with some successful findings. However, a detailed investigation on the use of probiotic for infected patients is still needed, particularly for its real efficacy. Universiti Putra Malaysia Press 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/40520/1/35.%20A%20Review%20on%20the%20Effects%20of%20Probiotics%20and%20Antibiotics%20towards.pdf Azman, Hazirah and Loong, Yik Yee and Abdul Aziz, Rushdan and Awang Hamat, Rukman and Abd Manap, Mohd Yazid (2013) A review on the effects of probiotics and antibiotics towards Clostridium difficile infections. Pertanika Journal of Science & Technology, 21 (2). pp. 293-302. ISSN 0128-7680; ESSN: 2231-8526 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2021%20%282%29%20Jul.%202013/02%20Page%20293-302.pdf
spellingShingle Azman, Hazirah
Loong, Yik Yee
Abdul Aziz, Rushdan
Awang Hamat, Rukman
Abd Manap, Mohd Yazid
A review on the effects of probiotics and antibiotics towards Clostridium difficile infections
title A review on the effects of probiotics and antibiotics towards Clostridium difficile infections
title_full A review on the effects of probiotics and antibiotics towards Clostridium difficile infections
title_fullStr A review on the effects of probiotics and antibiotics towards Clostridium difficile infections
title_full_unstemmed A review on the effects of probiotics and antibiotics towards Clostridium difficile infections
title_short A review on the effects of probiotics and antibiotics towards Clostridium difficile infections
title_sort review on the effects of probiotics and antibiotics towards clostridium difficile infections
url http://psasir.upm.edu.my/id/eprint/40520/
http://psasir.upm.edu.my/id/eprint/40520/
http://psasir.upm.edu.my/id/eprint/40520/1/35.%20A%20Review%20on%20the%20Effects%20of%20Probiotics%20and%20Antibiotics%20towards.pdf