Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells

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Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells

Styryl-lactones such as goniothalamin represent a new class of compounds with potential anti-cancer properties. In this study, we investigated the mechanisms of goniothalamin (GTN), a plant styryl-lactone induced apoptosis in human promyelocytic leukemia HL-60 cells. This plant extract resulted in a...

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Bibliographic Details
Main Authors:	Inayat Hussain, Salmaan Hussain, Osman, Md. Anuar, Din, Laily, Ali, Abdul Manaf, Ross, David
Format:	Article
Language:	English English
Published:	Elsevier 2003
Online Access:	http://psasir.upm.edu.my/id/eprint/40315/ http://psasir.upm.edu.my/id/eprint/40315/1/Loss%20of%20mitochondrial%20transmembrane%20potential%20and%20caspase-9%20activation%20during%20apoptosis%20induced%20by%20the%20novel%20styryl-lactone%20goniothalamin%20in%20HL-60%20leukemia%20cells.pdf http://psasir.upm.edu.my/id/eprint/40315/7/1-s2.0-S0887233303000511-main.pdf

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