In vitro antimicrobial activity of ethanol and water extracts of Cassia alata
Crude ethanol and water extract of leaves and barks from Cassia alata were tested in vitro against fungi, (Aspergillus fumigatus and Microsporum canis), yeast (Candida albicans) and bacteria (Staphylococcus aereus and Escherichia coli). C. albicans showed concentration-dependent susceptibility towar...
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| Format: | Article |
| Language: | English English |
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Elsevier
2003
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| Online Access: | http://psasir.upm.edu.my/id/eprint/40313/ http://psasir.upm.edu.my/id/eprint/40313/1/In%20vitro%20antimicrobial%20activity%20of%20ethanol%20and%20water%20extracts%20of%20Cassia%20alata.pdf http://psasir.upm.edu.my/id/eprint/40313/7/1-s2.0-S0378874102001460-main.pdf |
| _version_ | 1848849390440022016 |
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| author | Somchit, Muhammad Nazrul Reezal, I. Ismail, Elysha Nur Mutalib, Abdul Rahim |
| author_facet | Somchit, Muhammad Nazrul Reezal, I. Ismail, Elysha Nur Mutalib, Abdul Rahim |
| author_sort | Somchit, Muhammad Nazrul |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Crude ethanol and water extract of leaves and barks from Cassia alata were tested in vitro against fungi, (Aspergillus fumigatus and Microsporum canis), yeast (Candida albicans) and bacteria (Staphylococcus aereus and Escherichia coli). C. albicans showed concentration-dependent susceptibility towards both the ethanol and water extracts from the barks, but resistant towards the extracts of leaves. The degree of susceptibility varied, the water extract from barks showed bigger inhibition zone than the ethanol extracts (12–16 and 10–14 mm, diameter respectively). The growth of Aspergillus fumigatus and Microsporum canis were not affected by all types of the plant extracts. Results were comparable to standard antifungal drug Tioconazole (18 mm diameter) at equivalent concentration. The anti-bacterial activity of C. alata extracts on S. aureus was detected with only the leaves extracts using water and ethanol. The water extract exhibited higher antibacterial activity than the ethanol extract from leaves (inhibition zones of 11–14 and 9–11 mm, respectively). E. coli showed resistance to all types of extracts. Based on the current findings, it can be concluded that this plant has antimicrobial activity, which is as potent as standard antimicrobial drugs against certain microorganisms. |
| first_indexed | 2025-11-15T09:49:38Z |
| format | Article |
| id | upm-40313 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T09:49:38Z |
| publishDate | 2003 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-403132024-07-23T00:17:01Z http://psasir.upm.edu.my/id/eprint/40313/ In vitro antimicrobial activity of ethanol and water extracts of Cassia alata Somchit, Muhammad Nazrul Reezal, I. Ismail, Elysha Nur Mutalib, Abdul Rahim Crude ethanol and water extract of leaves and barks from Cassia alata were tested in vitro against fungi, (Aspergillus fumigatus and Microsporum canis), yeast (Candida albicans) and bacteria (Staphylococcus aereus and Escherichia coli). C. albicans showed concentration-dependent susceptibility towards both the ethanol and water extracts from the barks, but resistant towards the extracts of leaves. The degree of susceptibility varied, the water extract from barks showed bigger inhibition zone than the ethanol extracts (12–16 and 10–14 mm, diameter respectively). The growth of Aspergillus fumigatus and Microsporum canis were not affected by all types of the plant extracts. Results were comparable to standard antifungal drug Tioconazole (18 mm diameter) at equivalent concentration. The anti-bacterial activity of C. alata extracts on S. aureus was detected with only the leaves extracts using water and ethanol. The water extract exhibited higher antibacterial activity than the ethanol extract from leaves (inhibition zones of 11–14 and 9–11 mm, respectively). E. coli showed resistance to all types of extracts. Based on the current findings, it can be concluded that this plant has antimicrobial activity, which is as potent as standard antimicrobial drugs against certain microorganisms. Elsevier 2003-01 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/40313/1/In%20vitro%20antimicrobial%20activity%20of%20ethanol%20and%20water%20extracts%20of%20Cassia%20alata.pdf text en http://psasir.upm.edu.my/id/eprint/40313/7/1-s2.0-S0378874102001460-main.pdf Somchit, Muhammad Nazrul and Reezal, I. and Ismail, Elysha Nur and Mutalib, Abdul Rahim (2003) In vitro antimicrobial activity of ethanol and water extracts of Cassia alata. Journal of Ethnopharmacology, 84 (1). pp. 1-4. ISSN 0378-8741; ESSN: 1872-7573 http://www.sciencedirect.com/science/article/pii/S0378874102001460 10.1016/S0378-8741(02)00146-0 |
| spellingShingle | Somchit, Muhammad Nazrul Reezal, I. Ismail, Elysha Nur Mutalib, Abdul Rahim In vitro antimicrobial activity of ethanol and water extracts of Cassia alata |
| title | In vitro antimicrobial activity of ethanol and water extracts of Cassia alata |
| title_full | In vitro antimicrobial activity of ethanol and water extracts of Cassia alata |
| title_fullStr | In vitro antimicrobial activity of ethanol and water extracts of Cassia alata |
| title_full_unstemmed | In vitro antimicrobial activity of ethanol and water extracts of Cassia alata |
| title_short | In vitro antimicrobial activity of ethanol and water extracts of Cassia alata |
| title_sort | in vitro antimicrobial activity of ethanol and water extracts of cassia alata |
| url | http://psasir.upm.edu.my/id/eprint/40313/ http://psasir.upm.edu.my/id/eprint/40313/ http://psasir.upm.edu.my/id/eprint/40313/ http://psasir.upm.edu.my/id/eprint/40313/1/In%20vitro%20antimicrobial%20activity%20of%20ethanol%20and%20water%20extracts%20of%20Cassia%20alata.pdf http://psasir.upm.edu.my/id/eprint/40313/7/1-s2.0-S0378874102001460-main.pdf |